Category Archives: Detoxification

Cancer and weight

Detoxification enzyme polymorphisms

Detoxification enzyme

Detoxification enzyme polymorphisms and natural detoxification works well in body cleansing

Detoxification enzyme polymorphisms: Obesity and weight regulation

The effect of toxins on people’s lives is determined partially by the polymorphisms of phase I and phase II detoxification enzymes. Highly prevalent single nucleotide polymorphisms (SNPs) of glutathione transferees enzymes predispose to increased toxic loads. According to the experts at AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD, detoxification of heavy metals is an important task for the body which depends on specific proteins and enzymes that bind the metals and transport them out of the cells. Toxins impair central appetite regulation and have has many other effects besides directly lowering thyroid hormone levels, metabolic rate, and fat burning (fatty acid oxidation), they can damage the mechanisms by which hormonal and Neuro-regulatory signals control our appetite and behavior. These signals are finely choreographed and sensitive to environmental inputs.

To briefly review, the hypothalamic appetite control system is centered in the acute nucleus. It receives peripheral feedback from leptin, insulin, PYY, and adiponectin. Central inhibition of food intake is regulated by pro-opiomelanocortin (POMC) and cocaine and amphetamine regulated transcript (CART). Central stimulation of intake is modulated by Neuropeptide Y and agouti-related peptide (AgRP). The melanocortin system and its receptors, MC3R and MC4R, play a crucial role in appetite control. And to be more specifically, doctor Akoury reiterates that, MSH binds to MCR, suppresses appetite, stimulates the thyroid axis, and increases energy expenditure, brown fat temperature, and sympathetic activity. It is inhibited by TNF. Other downstream control sites also exist in the related areas of the brain. Reward centers also play a role and are targets for new drug research including the end cannabinoid and serotonin receptors. Leptin resistance is found in obesity.

Detoxification enzyme polymorphisms: Benefits of detoxing your body

Detoxification is the process of removing toxins from the body. The process to detoxify your body involves many different elements such as herbal detoxification regimens, change of diet and vitamin supplements. It is one of the best ways to rid your body of toxins, which can slow it down and make it unhealthy. The process of detoxification requires some discipline for one to realize the following benefits:

Physical Benefits – The most noticeable benefits of detoxification are the physical ones. Since the toxins store up in major organs, detoxification will help these areas the most. The affected organs include; the liver and stomach will begin to work more effectively. After the detox is completed, you may feel “lighter” and have more energy.

Mental Benefits – Toxins and free radicals that accumulate in the body can also affect brain functions. Before a detox, you may have trouble sleeping, chronic fatigue, and trouble with your concentration. Once you work through this process, many of these issues will gradually disappear.

Lifestyle Changes – As you progress through the body detox, you will begin to feel better physically and mentally. This feeling can be addictive and lead to changing your lifestyle to cut out bad elements which give your body those toxins. Quitting smoking, eating better, and getting more exercise are all actions which help protect the body. All these are essential in keeping a healthy and leaner weight. Nonetheless, many people are still struggling to achieve this and therefore if you or anyone you know is struggling with weight management, you can schedule an appointment with doctor Akoury today for the commencement of your recovery program.

 

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Natural weight loss

Understanding toxins and weight regulation

Understanding toxins

Understanding toxins and weight regulation is very important in the weight loss recovery process

Understanding toxins and weight regulation: Underlying mechanisms

The underlying mechanisms of toxins come in various ways as we will be discussion progressively. Toxins can alter the hormonal regulation of weight, a process that involves insulin, leptin, thyroid, cortisol, adiponectin, resistin, sex hormones, and gut hormones, including ghrelin, peptide (PYY), and cholecystokinin (CCK). And speaking to the experts at AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD, it is quite clear that understanding toxins and how they affect weight regulation are very important. And to start us off, the influence of toxins on metabolism occurs through 5 key ways including:

  • Mechanisms
  • Hormonal regulation,
  • Neuro-regulatory mechanisms,
  • Immune regulatory mechanisms,
  • Mitochondrial function, and
  • Oxidative stress.

Toxins alter thyroid hormone metabolism and receptor function leading to lowered metabolic rate. Important Neuro-regulatory mechanisms affected by toxins include hypothalamic satiety modulation through effects on peripheral and central inhibitors and stimulators of appetite, including leptin, cortisol, melanocyte stimulating hormone (MSH), and neuropeptide (NPY). Stress-induced autonomic dysfunction it also alters appetite and weight-control mechanisms. Toxins can influence weight through toxin-mediated increases in inflammatory cytokines (TNF-α, IL-6) on the peroxisome proliferator-activated receptor (PPAR) family of nuclear receptors promoting insulin resistance, and on melanocortin receptor (MCR) system altering central appetite regulation.

Counter-regulatory signals triggered by inflammation such as suppressors of cytokine signaling (SOCS) induce leptin resistance. Toxins alter mitochondrial energetics by damaging enzymes involved in fatty acid oxidation and thermogenesis. Oxidative stress influences weight via NFκ B-mediated mechanisms of gene transcription that control insulin resistance and inflammation. Other mechanisms may include direct effects of toxins on hepatic control of lipid and glucose metabolism, and on inflammatory cytokines

Understanding toxins and weight regulation: Where do toxins come from?

According to the AWAREmed health center, exposure to toxins originates from two main sources: the environment (external toxins) and the gut (breakdown products of our metabolism, or internal toxins). Both can overload endogenous detoxification mechanisms.

External toxins

The dangers from without the external toxins include chemical toxins and heavy metals. The heavy metals that cause the illest health are lead, mercury, cadmium, arsenic, nickel, and aluminum. Chemical toxins include volatile organic compounds (VOCs), solvents (cleaning materials, formaldehyde, toluene, and benzene), medications, alcohol, pesticides, herbicides, and food additives.

Infections (hepatitis C virus) and mold toxins (sick building syndrome) are other common sources of toxins. Our modern refined diet can be considered toxic because it places an extra burden on detoxification systems through excessive consumption of sugar, high fructose corn syrup (the two most important causes of elevated liver function tests),trans fatty acids, alcohol, caffeine, aspartame, foods made with genetically modified organisms (GMOs), and the various plastics, pathogens, hormones, and antibiotics found in our food supply.

Internal Toxins

Danger from within internal toxins includes microbial compounds (from bacteria, yeast, or other organisms), and the breakdown products of normal protein metabolism. Bacteria and yeast in the gut produce waste products, metabolic by-products and cellular debris that can interfere with many body functions and lead to increased inflammation and oxidative stress. These include endotoxins, toxic amines, toxic derivatives of bile, and various carcinogenic substances such as putrescence and cadaverine. Lastly, by-products of normal protein metabolism, including urea and ammonia, require detoxification. We appreciate that your weight regulation is not that simple and that is why AWAREmed health is offering treatment solutions tailored at transforming each individual’s life through increasing awareness about health and wellness and by empowering individuals to find their own inner healing power. For all your weight related concerns, schedule an appointment with doctor Akoury today.

Understanding toxins and weight regulation: Underlying mechanisms

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Obesity an addiction

Upper body obesity and health complications

Upper body obesity

Upper body obesity and health complications can be addressed by simple physical activities and change of lifestyle

Upper body obesity and health: Stress response

There is no doubt that the prevalence of obesity has increased dramatically over the past decades. This is now a global concern and more so the upper body obesity (UBO), which is associated with type 2 diabetes (T2DM), dyslipidemia, and hypertension. According to doctor Dalal Akoury MD, President and founder of AWAREmed health and wellness resource center, the associations describe the metabolic syndrome, a clustering of symptoms with insulin resistance as a core cause. Regrettably, the prevalence of obesity and metabolic syndrome is now above average deeming both conditions serious public health issues, requiring immediate professional redress. Now that I have set your mind thinking, if you are considering taking timely action, schedule an appointment with doctor Akoury today for the commencement of your recovery process. And as you make that consideration, let us now focus on the roles of HPA (Hypothalamic Pituitary Adrenal axis).

Upper body obesity and health: The role of hypothalamic pituitary adrenal axis

Speaking to the experts at AWAREmed health center, it is obvious that stress is a serious challenge to the natural homeostasis of an organism. Animals react to stress by producing a physiological stress response to regain equilibrium lost by the stressor. The stress response is characterized by acute behavioral and physical adaptations, including increased cognition, analgesia, gluconeogenesis, lipolysis, and inhibition of reproduction. Digging deeper, there are two major components of the stress response: the autonomic nervous system (ANS), which encompasses the sympathetic and parasympathetic nervous system, and the HPA axis. These systems work centrally and peripherally to produce several responses. The ‘fight or flight response’ is an active reaction to either confront the stressor or escape confrontation.

The ‘defeat response’ is when the individual does not engage in either the fight or flight response and ultimately ‘loses’ the confrontation; this is the primary stress response in modern society and is associated with HPA axis changes. Although the ANS is a key element of the stress response, the purpose of this article is to discuss the role of the HPA axis in obesity and metabolic disease. Having said that, doctor Akoury reiterates that stress can be caused by external stressors such as employment or social strains or by intrinsic stressors such as sleep deprivation. Although an acute short-term stress response is necessary for homeostasis recovery, chronic or prolonged stress responses can be harmful and may cause several diseases stated above. A study on women reported that history of depression was associated with hyperactivity of the HPA axis and decreased bone mineral density. In the past 30 years, numerous studies have shown that obesity and other metabolic risk factors are associated with lower socioeconomic status, job strain, sleep deprivation, and depression.

Finally, and because of these factors, we can’t sit without doing something towards containing the prevalence of obesity and overweight. Guided by that great need, doctor Akoury made a passionate decision of creating this medical center primarily help in the transformation of each individual’s life through increasing awareness about health and wellness and by empowering individuals to find their own inner healing power. Out of this many have benefited and you too can if only you can let us know of your problems by calling us on telephone number 843 213 1480 and we will address all your concerns professionally.

Upper body obesity and health: Stress response

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Glowing skin

Stimulating skin beauty using the vital foods

Stimulating skin beauty

Stimulating skin beauty using the vital foods for the perfect skin complexion

Stimulating skin beauty using the vital foods: Tea and Soymilk

We are all very keen on ensuring that we keep our skin texture appealing and attractive and because of this we are ready to spend heavily no matter the cost. Interestingly while speaking to the experts at AWAREmed health and wellness resource center under the able leadership of doctor Dalal Akoury MD, it is interesting to understand that all the ingredients we need in stimulating skin beauty are just within reach and at reasonable cost. Just to help you understand this well, studies are now confirming that caffeine in tea just like in coffee too may help to protect your skin against skin cancer. Caffeine essentially kills precancerous and ultraviolet-damaged skin cells by blocking a protein that they need to divide. For instance in a study where mice were subjected to harmful sunburn causing ultraviolet B rays, caffeine inhibited the formation of skin tumors.

Besides that, Soymilk may also help to preserve skin-firming collagen due to its richness in isoflavones. In one of the findings published recently it was established that mice fed on isoflavones and subjected to ultraviolet radiation had fewer wrinkles and smoother skin than the ones exposed to UV light but didn’t get isoflavones. The experts from these findings concluded that isoflavones help prevent collagen breakdown.

Stimulating skin beauty using the vital foods: Spinach and Pumpkin

Still on food stuff, spinach leaves boasts lutein, a carotenoid that protects your skin from UV damage. When buying spinach, pick the one right up in the light according to new research, published in the Journal of Agricultural and Food Chemistry, reveals that spinach stored continuously under the light for as little as three days boasted higher levels of vitamin C and preserved levels of K, E, folate and the carotenoids lutein and zeaxanthin. Like lycopene, beta carotene the compound that makes pumpkins orange protects your skin from UV damage. Beta carotene is also converted to vitamin A in the body, which helps to keep your eyes, bones and immune system healthy.

Finally, all the common food stuff we often ignore are very essential for the perfection of your skin quality, remember that what you eat contributes significantly to your general well-being and that includes your facial look and general skin quality. It is however very important that even as you follow good diet you will still needs to consult periodically with the experts who are experienced and has track records of their performance. Talking to doctor Akoury will be the genesis of your journey to acquiring that perfect look and not just on your face but also on your general skin on your entire body. I will now leave you to make that life changing phone call to doctor Akoury now and experience the joy of having that youthful face and skin texture.

Stimulating skin beauty using the vital foods: Tea and Soymilk

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lose weight

Discriminating obese and overweight people

Discriminating obese

Discriminating obese and overweight people is wrong and we must join forces to stop it

Discriminating obese and overweight people: How it affect both men and women

It is regrettable that at this point of time people are still living under certain siege of discrimination because of some health conditions that could be avoided like weight gain and obesity. Discriminating obese and overweight people a serious illegality which is very common the world over with the US taking the lead. I will be discussing some of the effects of this uncalled for habit and offer you solutions so that you can live your life freely and void of any discrimination. According to the experts from AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD, people who are affected by excess weight or obesity experience discrimination across a wide variety of settings, including healthcare, employment, schools, public transport sector, social amenities joints and interpersonal relationships.

Discriminating obese and overweight people: Social discrimination

Let us consider the employment settings, job seekers who are affected by excess weight are often less likely to secure job opportunities or even be recommended for promotion compared to their slimmer colleagues and in the very extreme they are also faced with lower remunerations and increased risk of job insecurity based on their weight alone.

In healthcare settings, obese patients often experience prejudice, apathy and lower quality of care from medical professionals, which may result in patients choosing to delay or forgo crucial preventative care to avoid additional humiliation.

Students also face weight-based victimization in educational sector from their peers, teachers and even parents, which may interfere with social support and educational achievement.

Weight stigma is even present in interpersonal relationships with friends, family and romantic partners, such that negative judgment invades almost all areas of the lives of people affected by obesity.

Discriminating obese and overweight people: Gender differences in weight gain stigma

Although both men and women are vulnerable to weight discrimination, their experiences may differ with respect to how much discrimination they are exposed to and the forms that it takes. Most notably, women seem to experience higher levels of weight stigmatization than men, even at lower levels of excess weight. Research suggests that women, especially those who are middle aged or with lower levels of education, experience weight discrimination at significantly higher rates than male peers. Moreover, women report weight discrimination at lower levels of excess weight than men. For example, men tend to report considerable stigmatization at a Body Mass Index (BMI) of 35 or higher, whereas women report experiencing notable increases in weight discrimination at a lower BMI of only 27.

North American ideals of physical attractiveness, which emphasize thinness as central to feminine beauty, may account for some of these differences. Women whose bodies deviate, even slightly, from physical beauty standards may be vulnerable to weight stigmatization. Given that thinness ideals have become deeply ingrained into our society and are heavily promoted by the mass media, diet industry and fashion industry, it’s not surprising to see widespread weight stigmatization toward women, even if they are not “obese.” For women, weight discrimination has been associated with poorer body image, low self-esteem, depression, anxiety, and a range of unhealthy eating behaviors, including binge eating. We must get out of this madness and scheduling an appointment with AWAREmed health center should be the starting point to getting a leaner body weight.

Discriminating obese and overweight people: How it affect both men and women

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