Tag Archives: Neuron

Motivational Interview So Important In Addiction Treatment

March 15, 2015

Crucial Stages of Motivational Interview as Part of Addiction Treatment

Addiction is a multifaceted issue that also needs to be given a multifaceted approach in treatment without which treating addiction will be a fallacy. There is required input and cooperation of the patient 100 percent. He has to have the will to quit using the drugs he is using; you can never force an addict to quit using a drug he has become addicted to. It also needs patience of both the doctor and the patient so that the addict will be able to completely recover from all the adverse effects of addiction especially during withdrawal. One of the ways through which an urge to quit using drugs can be imparted into an addict is through motivational interview. Motivational interview is often referred to as motivational therapy and us done by a motivational therapist. The main aim of the motivational therapist is to help the patient see the side effects that he is suffering as a result of the use of the abusive drug and help create a desire to quit using the drug in the addict. He will not try to victimize the addict or to oppose his views but uses the power of empathy to instill the desire to quit the use of the abusive drug into the addict.

Motivational Interview

For any motivational interview to be effective there is need of full cooperation from the addict. There is also need of input of an experienced motivational therapist to place the will to change from the use of drug abuse into the mind of the addict. The addict is the center of focus in motivational interview, he is the one who has to make the decision of whether to quit using the drugs or not. The motivational therapist is just there to help him make this decision by giving him a better option in quitting but he can’t decide for the addict, the addict has to own the decision to quit and that is when he is bound to succeed. In a journalistic point of view it appears that both the addict and the therapists are very crucial parties to this type of treatment because as much as the therapist may be good at his work. He may bear initial fruits in planting the desire to quit using the drugs in the mind of the addict but the addict must make the step of quitting the use of the drug.

Here are some crucial stages that the addict will be taken through by the help of the motivational therapist

  • Pre-contemplation
  • Contemplation
  • Preparation
  • Action
  • Maintenance and relapse

For effectiveness these stages should be followed in sequence, however if an addict may fall beck he should be encouraged to continue from where appropriate.

Pre-contemplation

This is the first stage in which the thought of changing has not even got into the mind of the addict. In most instances the drug users are in denial and they do not consider themselves as the right audience to the advice being offered. Here the will to change is not close even to the addict and it requires an input of an expert motivational therapist to let the drug addict see the need to overcome the addiction. During this stage, addicts do not consider change. They may not believe that their behavior is a problem or that it will negatively affect them or they may be resigned to their unhealthy behavior because of previous failed efforts and no longer believe that they have control over addiction. At this stage the therapist must be careful not be seen as opposing the lifestyle of the addict but as an empathizer who has placed his foot right in the moccasins of the addict. Here the therapist’s main goal is harmer the desire to quit using the drugs of abuse in the patient’s mind.

Contemplation Stage

At contemplation stage, patients are unsure about changing. They are weighing the benefits they get from the use of the drug against the benefits they will receive after quitting its use. At this stage the patients tries to look into the reasons why they can’t stop the use of the drug. Giving up an enjoyed behavior causes them to feel a sense of loss despite the perceived gain.  This is the stage where the patient needs the help of the motivational speaker most as he gets in conflict with himself. He is torn between stopping the use of the drug and continuing using it. He must know the advantages and disadvantages of quitting the drug use. The therapist will be of help in letting the addict choose wisely.

Preparation Stage

Motivational InterviewDuring the preparation stage, patients prepare to make a specific change. To test the waters of the new world, the addict may try using the drugs in lower doses and tests his body reaction to the deprivation. The therapist helps the patient to stay true to its course since the outcome of these experiments may make the addict to give up on the goal of quitting the drug use.

Action Stage

The action stage is the stage that needs more of the patient’s contribution to be successful. Many patients may fail once but with the help of the therapist they may get up and continue fighting addiction.  Every effort that the patient puts forward must be appreciated by the therapist as this gives the addict the morale to continue.

Maintenance and Relapse Prevention

Every motivational therapist would want his patient to reach this stage. However the addict may go through the initial stages many times before fully landing on this stage. Change is not always easy to deal with and any discouragement from the therapists over the addicts’ occasional slip may thwart his hopes of ever overcoming addiction and hence he may give up.

Finally, the need to quit using drugs of abuse is crucial in motivational interview; the therapist has to instill this in the addict failure to which the interview will bear no success. All the same addiction is a jail that many are chained but the need for liberation is the very reason for our existence. Here at AWAREmed we are dedicated to finding the best solutions to addiction and dependence on substances. Dr. Dalal Akoury (MD) is always in the mood of helping any patient to be addiction free. Do not hesitate to call on her for help in managing any sort of chronic pain or any type of addiction as well as other diseases.

Crucial Stages of Motivational Interview as Part of Addiction Treatment

Related articles
Facebooktwitterpinterestlinkedin

GABA Restoration In Addiction Therapy

March 8, 2015

Role of GABA restoration in addiction therapy

There are several drugs of pleasure that people use today. The problem is not exactly in the use of the drugs but rather in the effects they create in the brain. Addiction contrary to what many people think is not a problem with how frequent you take a drug but what even a single puff of or drop of a drug will cause to your brain and the entire nervous system. Composed of the individual nerve cells also known as neurons the nervous system serves as the network in the body. Without this network all communications between the nerve cells will be broken and a person will be incapacitated to even do a simple task as blinking. Typically, nerve signals are transmitted through the length of a neuron as an electrical impulse. When a nerve impulse reaches the end of the neuron it can jump over to the next cell using chemical messengers called neurotransmitters. Therefore without the neurotransmitters the nerves will not be able to send impulses over to other nerve cells in order to initiate specific actions. The neurotransmitters have vital functions in the central nervous system. In the central nervous system these neurotransmitters send impulses between neurons. The functions of the neurotransmitters is not limited to the central nervous system alone but are also crucial in the peripheral nervous system where they send impulses between neurons and gland cells. The peripheral nervous system is composed of nerves that link the central nervous system to the rest of the body.

There are two types of neurotransmitters, the inhibitory transmitters which are known to restore calm in the brain especially after the use of leisure drugs that are known to induce euphoric effects by raising the levels of dopamine and the excitatory neurotransmitters that fires the brain. GABA is one of the inhibitory neurotransmitters that counter the effects of leisure drugs and restores calm in the brain.

GABA restoration

GABA is one of the most abundant neurotransmitters in the central nervous system, and especially in the cerebral cortex. The brain cortex is where thinking occurs and sensations are interpreted. As mentioned above GABA is the primary inhibitory neurotransmitter brain and it helps in tranquillizing stressful, anxious and worrying thoughts. What happens with most drugs of leisure is that they cause instability in the brain leading to anxiety, stress and even depression. These are symptoms of low GABA. Addiction is a cause of low GABA as most drugs deplete GABA. There are several ways through which this can be medically corrected but those with addiction issues usually turn to their drugs as a means of self-medication but this only worsens the situation leading to anxiety and depression. Tranquilizers and downers are no better solutions to low GABA symptoms but finding a safe GABA regulation therapy may help in addiction treatment. The other cause for use of downers and tranquilizers is the rise in the level of norepinephrine. A rise in this neurotransmitter often induces the use of cannabis sativa.

The roles of GABA in the Brain

Made from glutamate in the brain cells, GABA works as an inhibitory neurotransmitter blocking nerve impulses. It is this neurotransmitter that inhibits the actions of dopamine when elevated in level by drug use. Glutamate acts as an excitatory neurotransmitter and when bound to adjacent cells encourages them to fire and send a nerve impulse. However, GABA does the opposite and tells the adjoining cells not to calm, not to send an impulse.

To those with inadequate level of GABA the activities of the excitatory neurotransmitters will not be inhibited and therefore the impulses they send will not be regulated and this often leads to anxiety disorders such as panic attacks, seizures, addiction, Parkinson’s disease and cognitive impairment.

GABA is the most effective neurotransmitter in inhibiting the transmission of nerve impulses from one neuron to another. When this happens it restores calmness in the brain however when drugs are used they inhibit the release of GABA, when GABA release is inhibited there will be more nerve transmissions occurring. These drugs inhibit the release of GABA by causing molecules to bind on neurons near GABA reducing its effect on the neurons. Benzodiazepines and other drugs are known to work in this style, they may also mimic the activities of GABA thereby inhibiting its transmission.

GABA rESTORATION

Need For GABA restoration in addiction Treatment

After a long term use of certain drugs, the level of GABA will be depleted to a point where it will be at an all-time low. This will lead to myriad of complications as the nerve impulses will be unregulated. This will lead to such problems as anxiety, depression, cognitive impairment and seizures among other diseases. Without restoring the level of GABA to healthy limits, any attempt to treat an addict will be ineffective.

Finally, Drug addiction treatment is a complex procedure that needs the input of an experienced integrative doctor. the health of neurotransmitters matters a lot and now that it is known that some drugs depletes these neurotransmitters there is need for treatment of addiction in a manner that restores the functions of the entire nervous system. This is why here at AWAREmed we are dedicated to finding the best solutions to addiction and dependence on substances. Dr. Dalal Akoury (MD) is always in the mood of helping any patient to be addiction free. Do not hesitate to call on her for help in managing any sort of chronic pain as well as other diseases.

Role of GABA restoration in addiction therapy

 

Related articles
Facebooktwitterpinterestlinkedin

Stem Cell Therapy May Offer an Effective Parkinson’s Disease Treatment

March 7, 2015

Stem Cell Therapy May Offer an Effective Parkinson’s Disease Treatment

The Parkinson’s disease has affected many people in the past and it still startles to know that this disease is still affecting millions of people across the globe. Doctors have been treating only the symptoms of this disease as there is no known cure of the Parkinson’s disease. Recently there has been lots of research on the field of integrative regenerative medicine to help in treatment of this disease. The stem cell therapy is one of the ways that have been investigated by researchers to establish if there is a possibility of this disease having a known cure which is effective.

Despite the fact that the Parkinson’s disease has no known cure, the cause of this disease is known. This disease is caused by the continued loss of dopamine-producing cells in the brain. Dopamine is a crucial brain chemical that helps to regulate movement and emotional responses among other functions.

When a person is suffering from this disease, he will suffer deficiency of dopamine. The Parkinson’s disease is known to target and kill dopamine-producing nerve cells, or neurons, in part of the brain called the substantia nigra. The effects of Parkinson’s disease on the nerve cells of the brain may be the reason for such problems in sleeping, motivation and thinking that Parkinson’s disease is known for but also it has been linked to the linked to the formation of clumps of a protein called alpha-synuclein in the brain. These abnormal protein clumps are called Lewy bodies and are dangerous in the body.

Continued death of the nerve cells results in Parkinson’s patients developing tremors and rigidity, as well as slowed movements. Other conditions that these patients will suffer from as a result of continued death of the nerve cells in the brain includes depression, sleeping disorders, dementia and even constipation. However dementia may be suffered at a much later stage when the damage on the nerve cells has spread widely. They may also lose their sense of smell.

Parkinson’s Disease

Due to the fact that depletion of dopamine causes Parkinson’s disease, doctors have been utilizing treatments that are useful in boosting the levels of dopamine din the brain. One of the most commonly used treatments is the use of a drug known as the Levodopa. This drug has been in use since 1960s when it was discovered. It works in a manner that supplements dopamine levels as it converts into dopamine while in the body. In this case the drug Levodopa stands in for the damaged neurons that ought to produce dopamine. Currently there are also other drugs that are used as dopamine to stimulate the nerve endings. Patients may also go through some therapies and put on special diets all aimed at improving the dopamine levels. In case the disease has advanced a patient may have to be treated through surgeries which may include deep brain stimulation with implanted electrodes. however, the treatments that have been mentioned above only work to mitigate on the effects of the symptoms of Parkinson’s disease but do not slow down or reverse the damage that the disease cause on the nerve cells in the brain. It has also been reported that even with the above treatments it reaches a time when the patient’s condition will deteriorate. There has also been a problem with early detection of the disease as mostly the disease is diagnosed lately after a patient has lost most of his dopamine and the nerve cells in the brain are already damaged. It is with the view of seeking a whole treatment for the disease that scientists began research on the ability of the stem cells to treat Parkinson’s disease.

The stem cell therapy may help

Parkinson’s disease is a dark medical field, its immediate cause isn’t known but scientists have today known which part of the brain is affected by this disease as well as the cells that are often affected by the disease. the stem cells which are known replicate several times giving rise to new cells are already being used to grow dopamine producing nerve cells in laboratories to aid the study of this disease. The stem cells are majorly used in the labs when the genetic cause of the disease is known. The disease destroys cells but through stem cells therapy, the damaged cells can be replaced by healthy new cells of the same type.

Research studies of 1980-90s bred hope

Parkinson's DiseaseIn 1980-90s researchers worked to find out if the cell replacement therapy could be used to quell the harmful effects of the Parkinson’s disease. The findings of these researchers have since been a foundation upon which current researchers increase the scope of their study on the effects of cell replacement therapy on the Parkinson’s disease. Particularly, Swedish, American and Canadian researchers have transplanted the developing nigral dopamine-producing neurons from human fetuses into animals and human patients with Parkinson’s disease. In these studies there were some great improvements while in other cases there were only modest changes.

A new study has since resurfaced. This study is much larger in scope and will include clinical trials. The study titled TRANSEURO aims at addressing the issues of consistency in efficacy as well as reduction in side effects associated with stem cell transplant. There is optimism that stem cell transplant to replace the damaged nerve cells could help in fighting this disease. Dr. Dalal Akoury (MD) is an expert in integrative medicine and a founder of AWAREmed Health and Wellness Center located at Myrtle Beach South Caroline. Visit her for more information on most lifestyle diseases.

Stem Cell Therapy May Offer an Effective Parkinson’s Disease Treatment

 

Related articles
Facebooktwitterpinterestlinkedin

Herbs That Increase Dopamine Level

February 25, 2015

Herbs That Increase Dopamine Level

Popularly known as the brain’s feel good hormone, dopamine is responsible for sending feelings of well-being and pleasure into the body.  Apart from this known function, other functions of dopamine include; control weight, energy levels, and supports brain and heart health. Without it, we would be more fat, unhappy, and tired. Dopamine is one of the most crucial neurotransmitters in the body. Dopamine has very many functions in the body but to many people it is famous for its good feeling effects that it is always identified with but this should not be the case as it has functions beyond the mesolimbic pathway. In the brain dopamine plays such roles as: It plays a big role in starting movement, and the destruction of dopamine neurons in an area of the brain called the substantia nigra is what produces the symptoms of Parkinson’s disease. Dopamine also plays an important role as a hormone acting to inhibit prolactin to stop the release of breast milk. Back in the mesolimbic pathway, dopamine can play a role in psychosis, and many antipsychotics for treatment of schizophrenia target dopamine. Dopamine is involved in the frontal cortex in executive functions like attention. In the rest of the body, dopamine is involved in nausea, in kidney function, and in heart function. Owing to its many functions that are all crucial, it is important that dopamine be in good levels for the optimal performance of the body.

Ginseng

Dopamine is crucial in our bodies but the use of drugs of abuse will lead to depletion of dopamine giving rise to some diseases like depression among others. Some drugs of leisure are loved for their euphoric feelings; they affect the normal production of brain chemicals. At the beginning they may induce a sudden surge in the production of feel good brain chemicals, however when you have used the drugs for some time they will lead to depletion in the levels of the brain chemicals such as serotonin and dopamine. In the brain the production of neurotransmitter happens naturally without intervention of any other drug. These basic neurotransmitters include; dopamine, serotonin, GABA, acetylcholine. The body also produces other chemicals known as endorphins which work as the body’s own opiates functioning to fight pain naturally.

These neurotransmitters have specific functions that they accomplish in the body. Each function is important and works in conjunction with the functions of the other neurotransmitters to make life what it ought to be. These functions are; Serotonin regulates sleep and appetite, Acetylcholine for processing information and memory, GABA acts as your calming neurotransmitter while dopamine is the feel good chemical, plays an important role in mood, energy, attitude, motivation.

When you use these drugs of pleasure thy hike the levels of dopamine in the brain beyond the accepted levels. This will force the brain to find a means by which to suppress the production of the neurotransmitter that has been hiked by drug use. naturally, the production of dopamine will be reduced by the brain after sensing that the hike in the levels of dopamine is caused by factors out of the body, therefore when a person who has been using drugs stops using them, the levels of dopamine and serotonin will be too low below the normal levels and this beckons such feelings of depression, anxiety, nervousness and lack of interest in everything. The level of dopamine in the body can however be restored naturally by use of herbs. Here are some of the herbs that are effective in restoring levels of dopamine even after drug use.

The Dopamine Boosters

St. John’s wort Ginseng– ginseng does not only increase the level of dopamine in the body but also works in rejuvenating, restorative, boosts energy and vitality and is tonic to the brain. Ginseng is often prescribed for patients fighting depression which is a common symptom of withdrawal from drug use. This herb is a better therapy for those who are under physical, emotional, mental or spiritual stress as it is a very strong antidepressant and adaptogenic. Ginseng promotes strong nerves, sound sleep, improves memory, clear thinking and enhances concentration.

Red clover -Red clover not only increases the dopamine levels in the brain but also nourishes the entire body, provides plenty of protein, B vitamins, and calcium, all essential brain nourishing nutrients.

St. John’s wort -St. John’s wort is effective against mild to moderate depression, alleviates anxiety, insomnia, and irritability and eases pain. It increases the level of dopamine in the brain as well.

Peppermint– contrary to what many people believe, peppermint is not psychoactive but is rather sedating, stimulating and pain relieving. Peppermint is one of the many herbs that can be used to restore the level of dopamine in the brain and restore the normal bodily functions.

Fenugreek -Fenugreek is a herb and a spice commonly eaten in many parts of the world, and has been used for centuries by practitioners of Ayurvedic Herb medicine and Traditional Chinese Medicine. It also increases the levels of dopamine and so can be used by patients whose dopamine level have floored as a result of drug use.

Today the patients have varied options when it comes to restoring the levels of testosterone in the body, however going the natural way is more beneficial as it is safe and inexpensive as well. It is good to note that by increasing the level of dopamine in your body, you are setting good grounds for addiction treatment and recovery. However, these problems need to be treated effectively through integrative medicine. Dr. Dalal Akoury (MD) is an expert at this.  Call her on (843) 213-1480 for help.

Herbs That Increase Dopamine Level

 

Related articles
Facebooktwitterpinterestlinkedin

GABA Metabolism in the CNS in Addiction

February 14, 2015

GABA Metabolism in the CNS in Addiction

What is GABA?

Known as Gamma-Amino Butyric acid, it is an amino acid that performs functions of neurotransmitters in the brain.it is the most abundant neurotransmitters occurring in the central nervous system (CNS).it  acts as an inhibitor of transmissions in the brain thus in the process calming down activities in the nervous system. It is found as a supplement in which it acts as a natural tranquilizer. It has been shown to increase levels of human growth hormones thus is very popular among body builders.

The Neurotransmitters Question

The brain is made up of millions of cells. Communication takes place from one brain region to another through neurotransmitters. Neurons are individual cells of the nerves that make up the nervous system. They serve as the wiring for the body to transmit information form one region to another. The electrical signals generated are transported through the neurons as a single impulse. Ones the impulses reaches the end of the neurons, it is transmitted to the other cell through neurotransmitters.

The central nervous system consists of the spinal cord and the brain. The two consist of neurotransmitters which pass from one end of the neuron to another. The peripheral nervous system which is made up of nerves that run to the rest of the body. The nerves transmit chemical signals from one neuron t adjacent gland cells and muscles.

GABA and glutamate are the most abundantly occurring neurotransmitters in the nervous system. The two are in abundance in the cerebral cortex which is the region where interpretation of sensation takes place and thinking occurs. The ending of the neurons are made up of sac like structures which are filled with neurotransmitters.

GABA

When the chemical and electrical signals reach the end of the neurons, they trigger the sacs to release neurotransmitters to act as a bridge between one nerve cell and another. The spaces called synapses act as a bridge through which signals pass to the other cells. On reaching the other neuron, the neurotransmitters attach to the cell receptors. This triggers the electric impulse to move from the end of the nerve cell neuron to the other cell completing the message transmission and triggering and effect.

Role of GABA In the Brain

It is formed in the cells of the brain from glutamate. GABA acts as an inhibitory neurotransmitter which simply means that it blocks nerve impulses in the brain. On the other hand, glutamate from which GABA is formed is an excitatory neurotransmitter. When it binds to cells adjacent to it, it activates them to send impulses throughout the brain from one cell to another. GABA instead of telling the brain to activate and send impulses, it tells it he opposite. It stimulates the brain not to send nerve impulses from one cell to another.

In the absence of GABA nerve cells tend to activate more often sending signals regularly. Disorders associated with anxiety such as headaches, addiction, panic attacks, Parkinson syndrome, cognitive impairment and seizures are all linked to low activity of GABA.

It naturally hinders nerve impulses transmission from one cell to another. It brings about a calming effect in the process. The best way to understand the significance of GABA is by understanding the effects of caffeine on the brain. Caffeine acts as an inhibitor of the release of GABA. When the levels of GABA are low in the brain, more nerve transmissions take place. This leads to the sensational feeling that one gets when they takes coffee. This feeling is as a result of activity of glutamate with less GABA.

The reason why, caffeine does this is simply because other molecules tend to bind with the neurons near the site where GABA binds with these neurons. This is exactly the way that basic tranquilizers like barbiturates and Benzodiazepines work. They increase the effects of GABA in the body which in turns inhibits the transmission of nerves.

GABA Metabolism

It is synthesized in a metabolic path known as the GABA shunt. The first step in GABA formation uses a-ketoglutarate that  is formed from metabolism of glucose in the Kreb’s cycle. Afterwards a-ketoglutarate is processed by a-oxoglutarate to form glutamate. In the final process, the glutamate undergoes decarboxylation to form GABA through the glutamic acid decarboxylase enzyme. Like other neurotransmitters, GABA is stored in the synaptic vesicles of the brain and is only released when depolarization of the presynaptic membrane takes place.

GABA

GABA and Addiction

Alcohol consumption leads to loss of coordination of the motors as well as sedation as other high levels of inhibitory transmitters do. Studies therefore show that GABA effects contribute to some effects of alcohol in the brain. Past studies show that, GABA as an inhibitory neurotransmitter is affected by alcohol consumption. Continuous alcohol consumption leading to addiction lead to decline in GABA receptors found in the brain and his reduces the ability of the neurotransmitter t bind with cell receptors.

In this case, the body is forced to find ways to compensate for the declined levels of GABA neurotransmitters. These effects are responsible for brain function changes that lead to things like dependence and alcohol tolerance. When one withdraws from alcohol, the stimulating effects on the neurotransmitter disappear. The body has very few GABA receptors needed to balance the effects of excitatory neurotransmitters. Because of this the brain has too many excitatory nerve signals being transmitted. This translates to psychological and physical effects of alcohol addiction and withdrawal.

Dr. Dalal Akoury has years of experience with patients of addiction and other health conditions. This enables her to provide wise counsel to patients who may be going through certain health conditions. Many of these patients have gotten better and they now bear witness to her god works. To become part of this community and to receive regular health and awareness tips that will befit you, visit www.awaremednetwork.com today.

GABA Metabolism in the CNS in Addiction

Related articles
Facebooktwitterpinterestlinkedin

  • Recent Posts

  • Blog Categories