Tag Archives: NAD

Cocaine addiction

Rebuilding Neurotransmitter for addiction solution

January 13, 2017
Rebuilding Neurotransmitter

Rebuilding Neurotransmitter for addiction solution very essential in keeping immunity system free from drug abuse

Rebuilding Neurotransmitter for addiction solution: Recovery using Intravenous NAD & amino acids

Addiction is a disease and not a moral weakness as it was used to be seen in the past. Like any other disease, treatment is very essential and it should begin with the rebuilding neurotransmitters. This way, we will be addressing the core problem in all areas including body and mind. The successful therapy will depend on address both problems simultaneously because the health of both depends on the unity of both that facilitates the health and balance in the mind and body thereby providing highly effective therapy for addiction. Meaning that if you detoxify, or withdraw, from alcohol or a drug, without addressing the conditions in the body that create fatigue, depression, and anxiety, then relapse is more likely moments after the therapy has been incomplete. Similarly, if you withdraw from a substance and do not understand the psychological and spiritual issues that promoted the need for it, then relapse is likely and the hard lessons of disease (addiction) shall not have been learned says doctor Dalal Akoury MD, President and founder of AWAREmed health and wellness resource center.

Rebuilding Neurotransmitter for addiction solution: The body

Integrative, or, functional medicine provides the tools to assess and treat the conditions in the body that contribute to fatigue, depression, and anxiety, thereby increasing the likelihood of chemical dependency.  This include:

  • Nicotinamide adenine dinucleotide (NAD) deficiency
  • Neurotransmitter deficiency (serotonin, GABA, adrenaline, noradrenaline, dopamine, etc)
  • Metabolic cofactor deficiency
  • Pyroluria
  • Hypothyroidism
  • Adrenal fatigue
  • Intestinal yeast overgrowth
  • Delayed-onset food sensitivities
  • Gluten intolerance

These “terrain issues” in the body need to be properly treated in order to make detoxification easier and to prevent relapse.

Rebuilding Neurotransmitter for addiction solution: The mind and the spirit

Away from the body, addiction is also a disease in the mind. The fact that the mind rules the body is, in spite of its neglect by biology and medicine, the most fundamental fact which we know about the process of life. The origins of most physical disease are within consciousness. The body is the messenger of the conflicts, sustained fears, suppressed emotional traumas, disturbed patterns of thinking, and other imbalances that lie within the conscious and unconscious mind. Many people have painful childhood experiences, including patterns of neglect, smothering control, abandonment, and emotional, physical and sexual abuse.

Later on, there can be failed relationships, years of marital conflict, and the pain of loneliness. Many experience decades of unfulfilling employment, foiled personal creativity and the quiet desperation of a slowly dying spirit. These life experiences contribute to relentless anxiety, depression, denied emotions, destructive beliefs, hopelessness, helplessness, “giving up”, and an endless variety of recurrent stresses. And remember that the emergence of disease of any kind is the body’s way of getting your attention and inviting this self-exploration, thereby offering true healing which becomes possible by rebuilding neurotransmitters. Finally, having been with us all this time, we would not have done you any justice by leaving your concerns unaddressed, and for us to do that, you need to schedule an appointment with doctor Akoury today and all your concerns will be addressed professionally.

Rebuilding Neurotransmitter for addiction solution: Recovery using Intravenous NAD & amino acids

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Nicotinamide Adenine Dinucleotide (NAD)

January 13, 2017
Nicotinamide Adenine Dinucleotide

Nicotinamide Adenine Dinucleotide (NAD) and did you know that for every beverage alcohol you take about 2 to 8 percent is lost through urine, sweat, or the breath?

Nicotinamide Adenine Dinucleotide (NAD): Acetaldehyde and Alcoholism

Did you know that for every beverage alcohol you take about 2 to 8 percent is lost through urine, sweat, or the breath? This means that the other 92 to 98 percent is metabolized by your body. All ethyl alcohol which is broken down in the human body is first converted to acetaldehyde, and then this acetaldehyde is converted into acetic acid radicals also known as acetyl radicals. Acetaldehyde is a poison which is a close relative of formaldehyde. Acetic acid is the essential component of vinegar. The acetic acid radical is the combining form of acetic acid. This acetic acid radical combines with Coenzyme A to form acetyl-CoA. The acetyl-CoA then enters the Krebs cycle, which is the basic powerhouse of the human body. Inside the Krebs cycle, this acetyl radical is eventually broken down into carbon dioxide and water.

According to the experts from the AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD, there are three different enzymes the body uses to convert alcohol to acetaldehyde. The three enzymes work by stripping two hydrogen atoms off from the alcohol molecule thereby converting the alcohol molecule into a molecule of acetaldehyde says doctor Akoury. We are going to consider the three enzymes progressively in this article.

Nicotinamide Adenine Dinucleotide (NAD): The Three Alcohol Enzymes

The three enzymes which can convert alcohol to acetaldehyde are:

  • Alcohol dehydrogenase (ADH) ·
  • Cytochrome P450 (CYP2E1) ·
  • Catalase

Each of these enzymes is found in different parts of the body and each of them handles the hydrogen atoms which are stripped off from the alcohol molecule in a different way. For the purpose of this article, we are going to discuss the first one and proceed with the rest of the subsequent postings.

Alcohol dehydrogenase

The name “alcohol dehydrogenase” sounds quite a mouthful, but it is self-explanatory if we break it down into its component parts. “de-” is a prefix which means “to remove”. We find it in such words as “dethrone” which means “to remove from the throne”. “-use” is a suffix which means “enzyme”. Any time you see a chemical term which ends in the suffix “-as” you know that you are dealing with an enzyme. “hydrogen” means “hydrogen” of course. So “de-hydrogen-ase” means “an enzyme which removes hydrogen atoms”, and “alcohol dehydrogenase” means “an enzyme which removes hydrogen atoms from the alcohol molecule”. The name alcohol dehydrogenase is sometimes abbreviated to ADH.

ADH is the workhorse of the alcohol enzymes–it breaks down the majority of the alcohol that enters the human body. Alcohol dehydrogenase is actually the name for a family of enzymes which break down alcohol–each of which has a slightly different molecular structure. Researchers have identified as many as 10 varieties of the alcohol dehydrogenase molecule. All of them bring about the same chemical reaction–the difference is that some varieties of alcohol dehydrogenase work more efficiently than others. As we shall be seeing later, these variations in the alcohol dehydrogenase molecule can explain why some individuals react differently to alcohol than others.

The alcohol dehydrogenase molecules do their work primarily in the stomach and the liver, although traces of them are found in other tissues as well. The hydrogen which is released when alcohol dehydrogenase turns alcohol into acetaldehyde is bound to a compound called NAD+ (Nicotinamide Adenine Dinucleotide) to form NADH (this is short for Nicotinamide Adenine Dinucleotide plus Hydrogen). Alcohol dehydrogenase does its work in the cellular fluid (cytosol) of the cell. The wordings in this article may be technical but necessary in understanding the dangers of substance abuse. You may want to seek for more clarity from the experts at AWAREmed today.

Nicotinamide Adenine Dinucleotide (NAD): Acetaldehyde and Alcoholism

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alcoholism

Understanding NAD (Nicotinamide Adenine Dinucleotide) role

January 12, 2017
Understanding NAD

Understanding NAD (Nicotinamide Adenine Dinucleotide) roles requires greater degree of professionalism

Understanding NAD (Nicotinamide Adenine Dinucleotide) roles: Cytochrome P450 2E1 (CYP2E1)

In light social drinkers nearly all the alcohol consumed is taken care of by alcohol dehydrogenase. However, the enzyme Cytochrome P450 2E1 (abbreviated CYP2E1) becomes quite active in metabolizing alcohol in chronic heavy drinkers. CYP2E1 does its work in the liver. The hydrogen released by this reaction is bound to oxygen and to NADPH to form water and NADP+. This reaction takes energy rather than producing it. CYP2E1 does its work in the microsomes of the cell. This is sometimes referred to as MEOS (Microsomal Ethanol Oxidizing System). CYP2E1 is a member of the Cytochrome P450 enzyme family as a better way of understanding NAD says doctor Dalal Akoury MD, President, and founder of AWAREmed health and wellness resource center. And now let’s turn to the last type of enzyme as stated previously.

Understanding NAD (Nicotinamide Adenine Dinucleotide) roles: Catalase

Catalase is found in tiny organs inside of cells called peroxisomes. Catalase is found all over the human body. When catalase turns alcohol into acetaldehyde the hydrogen which is released is bound to hydrogen peroxide molecules which then become water. Although catalase is active everywhere in the body, catalase is of particular interest to researchers because it metabolizes alcohol in the brain. The acetaldehyde released into the brain by the metabolism of alcohol by catalase has the potential to combine with neurotransmitters to form new compounds known as THIQs (tetrahydroisoquinolines, also sometimes called TIQs). Some researchers believe that THIQs are the cause of alcohol addiction and that the presence of THIQs distinguishes addicted drinkers from social drinkers. Other researchers strongly dispute the validity of the THIQ hypothesis of alcohol addiction. The actual role of THIQs remains controversial and calls for further research.

How Acetaldehyde Dehydrogenase Works

Acetaldehyde dehydrogenase does its work in the mitochondria of cells and removes a hydrogen atom from acetaldehyde to produce an acetic acid radical. This hydrogen atom combines with NAD+ to form NADH. There are several varieties of aldehyde dehydrogenase found in the human body. The one which normally breaks down acetaldehyde is called ALDH2. There is another variety aldehyde dehydrogenase found in the human body which is called ALDH2*2. ALDH2*2 is only about 8% as efficient as ALDH2 in metabolizing acetaldehyde. Some East Asian people have ALDH2*2 instead of ALDH2 in their bodies. These individuals find the effect of alcohol to be very unpleasant and that is going to form part of our discussion in the next article which I am persuaded you don’t want to miss.

Finally, doctor Akoury reiterates that the aldehyde dehydrogenase enzymes are found in many tissues of the body, but are at the highest concentration in the liver further explaining why alcohol addiction can be very dangerous to your health. And having known that, it will interest you to note that, the formation of AWAREmed health center was not just for the purpose of creation awareness about the effects of substance abuse, but also for finding the ultimate solution. And that is why away from creating awareness, doctor Akoury’s practices also focuses on the personalized medicine through healthy lifestyle choices that deal with primary prevention and underlying causes instead of patching up symptoms making her your best choice.

Understanding NAD (Nicotinamide Adenine Dinucleotide) roles: Cytochrome P450 2E1 (CYP2E1)

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Substance Abuse: Natural Treatment Care Model

October 13, 2014

A Continuous Care Model for Substance Abuse

Substance abuse

Substance Abuse

Drug and substance abuse is more prevalent in todays society than we think. Did you know that 1 in every 10 Americans are addicted? However, only 11% of that population actually receive the treatment they actually need. Addiction patients’ biggest dream is the day they will break the chains of their addiction to these substances. These proven therapies are a comprehensive intregravtive approach to addiction treatment for alcohol, and substance abuse.

Natural Healthy Detox NAD and Intravenous Amino Acid Therapy for Substance Abuse

Nicotinamide Adenine Dinucleotide often abbreviated as NAD is a metabolic co-enzyme and has the important job of structuring, repairing, and remodeling every cell in the body. These specialized enzymes require constant replenishment in the body. Unfortunately, alcohol and substance abuse prompt the human brain to reorganize, particularly on a cellular level. This process, neuroadaptation, is directly responsible for addiction-related brain damage and depletion of neurotransmitters. NAD IV therapy can be used to replenish the drained enzymes and target brain restoration. The intravenous amino acid therapy focuses on biochemical detoxification of the body and brain from the effects of addiction.

Liver Detox for Substance Abuse with Amino Acids

Liver is a vital organ in the body. In most cases the liver is exposed to toxicity that may impair its functions if necessary actions are not taken to clear the mess- detoxify it. Amino acids can be used in detoxing the liver and restore its health. There are several essential amino acids however these two are very important in detoxifying the liver; valine. This is necessary for muscle metabolism and the repair of tissues. It can be useful in the treatment of liver and gallbladder disorders. Another amino acid that is equally important in detoxing the liver is methionine. This amino acid aids in the production of sulphur, which is necessary for normal metabolism and it is also essential for the synthesis of hemoglobin and glutathione that fights against free radicals.

Exercise for Substance Abuse Treatment

Exercise plays a vital role in achievement of healthy wellbeing. The body is made up of muscles that need to be strengthened in order to support the health of the body. Through exercise the body gets detoxified through sweating. Exercise also improves the metabolic functions of the body. Exercise aids the liver in detoxifying the body therefore relieving the liver from the burden of accumulated filtrate of toxins from alcohol and substance abuse. Exercise also strengthens the heart and improves the flow of blood hence increasing the rate at which the waste products are removed from the body.

Meditation for Substance Abuse Treatment 

Meditation is a vital part of healing your mind body and spirit. Meditation is promoted to have many health benefits. Meditation is a perfect way to detox the mind and restore calmness throughout the body. However, it seems it serves more than just restoring calm and detoxing the mind; it also detoxifies the liver. It is argued that when the digestive system works well there is less buildup of waste in the liver. Good digestion is received when the body, mind and spirit are in synchrony. Meditation helps the body, the mind and the spirit to have good communication and enables proper metabolic functions of the body which is vital in liver health.

Hormonal Restoration for Substance Abuse Treatment

As discussed earlier, hormones are vital in a person’s body. They are the chemical messengers that are secreted directly into the blood. Without these hormones certain vital functions of the body cannot be accomplished. There are hormones that are responsible for metabolic functions. Sometimes hormonal fluctuations may interfere with the metabolic functions of the body leading to a liver overburdened with toxins. In such a scenario hormonal restoration becomes necessary to restore the health of the liver and the entire body.

Psychoneuro-Endocrine-Immune Restoration for Substance Abuse

The neuroendocrine and immune systems communicate bidirectionally. The neuro-immune-endocrine interface is mediated by cytokines acting as auto or endocrine factors regulating pituitary development, cell proliferation, hormone secretion, and feedback control of the hypothalamic-pituitary-adrenal (HPA) axis. Restoring the psychoneuroendocrine immune system beefs up the security of the body to fight unwanted pathogens hence vital in protecting the liver after detoxification.

Adrenal Rehabilitation for Substance Abuse

Adrenal glands play a major role in the body as it is the site on which many hormones are produced. However, alcohol and substance abuse may affect the adrenal glands making it inadequate to perform its function of secreting vital hormones that will keep the body in perfect health. After detoxifying the liver, the adrenal restoration becomes a vital procedure to ensure good liver health as well as body health.

Continuing Care for Substance Abuse

Substance abuseAfter adrenal rehabilitation and liver detoxification, there is still need to continue providing care to those facing substance abuse. This will mean that he/she should maintain the good practices of health. It will also involve consolidating all the good practices that will keep he/she fit and away from issues with substance abuse.

Finally, you need more information to stay away from dependence on substance and drugs as these have crippled societies and that is why here at AWAREmed we are dedicated to finding the best solutions to addiction and substance abuse. Dr. Dalal Akoury (MD) helps any patient to be addiction free. Do not hesitate to call AWAREmed for help in managing type of addiction as well as other diseases.

A Continuous Care Model for Substance Abuse

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IV NAD in Cancer Treatment

September 26, 2014

IV NAD as an Alternative cancer treatment

What is NAD?

IV NADNicotinamide Adenamide Dinucleotide (NAD) is an important molecule in the body of humans that is related to the process of production of energy required for all life activities. Basically, the food that we eat is usually broken down through a complex biochemical process to produce this molecule. The NAD molecule that is produced is then used to transport hydrogen at the cellular level. The combination of hydrogen that is carried by this molecule with oxygen within the mitochondria of the cell produces energy and water as byproducts of the reaction. The energy, which is produced in the form of a molecule called ATP, is what drives the processes of life in the body of a normal human being.

For healthy individuals, the importance of NAD cannot be overemphasized. First, availability of the molecule in sufficient amounts is necessary for one to experience a feeling of overall physical energy. Further, having sufficient amounts of NAD in the body is associated with good mental health, increased libido and overall good health. All these are positive attributes that make this molecule an important determinant of how healthy a person is at any given time. The reverse is true; deficiency of NAD in the body often leads to prolonged fatigue and other related illnesses.

Relationship between NAD and Cancer

There is a very complex relationship between the NAD molecule and different types of cancer. To begin with, the molecule is a byproduct of a complicated biochemical process known as the citric acid cycle in the cells. At the start of the citric acid cycle is vitamin B3, an important nutrient that is derived from good nutrition. Therefore, vitamin B3 is an important precursor for the production of NAD in the body.

One of the most important types of vitamin B is Niacin. This is a chemical that is produced in the body of a healthy individual and its function is to produce special enzymes that are required for the proper production and utilization of NAD. The enzymes are also useful in that they ensure that the Kreb’s cycle within the cells progresses without any major interruption. In the event that the cycle is interrupted as a result of lack of coenzymes, which can be traced back to insufficient niacin in the body, the cells of the body get exposed to the possibility of development of cancer.

The link between deficiency of NAD and possible development of cancer can best be understood when one considers what happens to the cells of the body when the normal Kreb’s cycle is interrupted with. Under such conditions, there is increased production of lactic acid and fermentation as the body cells seek to get a new source of energy. With increased fermentation, there is a rise in the level of lactic acid within the cells. It is such anaerobic conditions that precipitate the conversion of somatids into fungi – like microorganisms that have been found to play a key role in inducing changes in otherwise normal and healthy body cells into toxic and cancerous ones.

Therefore, lack of niacin leads to deficiency in NAD which in turn causes a decline in the amount of important enzymes. The end result is that the cell environment becomes toxic, characterized by an increase in lactic acid, conditions that ultimately lead to cancer development.

How IV NAD works as an alternative cancer treatment

There are several specific ways in which IV NAD treatment works as a component of an alternative cancer treatment regimen. What one needs to know, however, is that when administered intravenously, the treatment is quite effective because then NAD is transported to the brain of patient. Since this is where the receptors of the molecule are located, intravenous administration of this treatment produces intense and long standing results in patients. It is here that the effects of the molecule are felt before being replicated in the other parts of the body.

One way in which IV NAD treatment can be useful for cancer patients as part of the alternative treatment therapy being used lies in its characteristic as a strong detoxification agent. Basically, NAD has been known to rid the cells of all manner of toxins that accumulate over the course of time, particularly under conditions of a debilitating condition like cancer. Therefore, when administered to cancer patients, IV NAD treatment enhances the overall health of the patient by cleansing the cells of the body of all manner of toxins.

Another way in which this form of treatment can be useful as an alternative cancer treatment technique lies in its ability to boost the effectiveness of other forms of treatment that are in use. This treatment is effective in enhancing the ability of pharmacological drugs being used as treatment to kill cancerous cells in the body of a patient. The exact mechanism by which the treatment enhances the cancer – killing ability of chemotherapy while preserving normal body cells is a topic of research.

IV NADTherefore, common understanding is that niacin itself shown anti- cancer properties and when used as part of an IV NAD treatment in cancer patients, is able to enhance the effectiveness of other standard therapies being used.

IV NAD is offered at AWAREmed Health and Wellness Resource Center as part of alternative cancer treatment therapy. Dr. Dalal Akoury has won accolades in the practice of alternative treatment for cancer. You can pay her a visit for this service as well as other natural methods of overcoming NAD deficiency in the body. We are located in Myrtle Beach, South Carolina.

IV NAD as an Alternative cancer treatment

 

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