Risk Factors of Breast cancer
Risk Factor of Breast cancer -Role of alcohol
The risk factors of breast cancer can be life threatening. We must be positive and prevent breast cancer from our life.
Breast cancer normally is forms in tissues of the breast and the common type of breast cancer include ductal carcinoma, which instigates in the lining of the milk ducts a thin tube transporting milk from the lobules of the breast to the nipple.
The other type of breast cancer is lobular carcinoma, which instigates in the lobules (milk glands) of the breast. Invasive breast cancer is that has extended from where it began in the breast ducts or lobules to adjacent normal tissue. Breast cancer occurs in both men and women, although male breast cancer is rare.
Risk Factor of Breast cancer – Connection between alcohol consumption and cancer
Researchers while studying particular enzyme established that a biological molecule that accelerates chemical reactions commonly known as CYP2E1. Their findings offer a possible target to improve outcomes for patients in the later stages of the cancer disease. This enzyme has been implicated in various liver diseases associated with alcohol consumption, Alcoholic Liver Disease (ALD), as well as diabetes, obesity and cancer.
The objective of the study was to understand why an enzyme known to function mainly in the liver was found to be profoundly present in some types of breast cancer tissues. The study also wanted to explore what other activities this enzyme might have that regulate the development of breast cancer and their findings established that the enzyme breaks down various molecules within cells including alcohol. The by-products of this metabolism include reactive oxygen species (ROS), occasioning in something called oxidative stress, in normal physiological conditions this aids cellular functions, whereas when concentrations of ROS are high or oxidative stress becomes chronic, cells can be seriously damaged.
Previous studies have also shown that the enzyme is most strongly expressed in early stages of breast tumors rather than more developed tumors and scientists believe that it contributes to the progression of breast cancer. The study, published in Breast Cancer Research, found that depending on the stage of the breast cancer, high levels of the enzyme can help cells survive during stress. It was also found that inhibiting the activity of the enzyme in cells with high migratory potential promoted cell migration a process linked to cancer spreading known as metastasis.
Risk Factor of Breast cancer – Causes and risk factors
Up to now it is still not very clear the causes of breast cancer and as a result of this it may be difficult to say authoritatively why one lady may develop breast cancer and another may not. However the risk factors are known, some of these can change the likelihood that someone may develop breast cancer. There are some factors you cannot do anything about, but there are some you can change. For example:
Alcohol
Your risk of developing breast cancer can increase with the quantity of alcohol you consume regularly. Research shows that, for every 200 ladies who regularly have two alcoholic drinks daily, there will be three more ladies with breast cancer compared with those who do not drink at all.
Age
The risk of developing breast cancer progresses as you get older. Breast cancer is most common among women over 50 majority of these ladies have been through the menopause. 8 out of 10 breast cancer cases occur in women over 50. All women between 50 and 70 years of age should be screened for breast cancer every three years as part of the NHS Breast Screening programme.
Genetics
If you have close relatives who have had breast cancer or ovarian cancer, you may have a higher risk of developing breast cancer. However, as breast cancer is the most common cancer in women, it is possible for it to occur more than once in the same family by chance.
Most breast cancer cases are not hereditary. However, particular genes, known as BRCA1 and BRCA2, can increase your risk of developing both breast and ovarian cancer. It is possible for these genes to be passed on from a parent to their child. If you have, for example, two or more close relatives from the same side of your family who have had breast cancer under the age of 50, you may be eligible for surveillance for breast cancer or for genetic screening to look for the genes that make developing breast cancer more likely.
Previous diagnosis of breast cancer
If you have previously had breast cancer or early non-invasive cancer cell changes contained within breast ducts, you have a higher risk of developing it again, either in your other breast or in the same breast again and so you need to be in constant touch with your doctor for review.
Previous benign breast lump
A benign breast lump does not mean you have breast cancer, but certain types of lump may slightly increase your risk of developing it. Certain benign changes in your breast tissue, such as atypical ductal hyperplasia (cells growing abnormally in ducts) or lobular carcinoma in situ (abnormal cells inside your breast lobes), can make getting breast cancer more likely.
Breast density
Your breasts are made up of thousands of tiny glands (lobules), which produce milk. This glandular tissue contains a higher concentration of breast cells than other breast tissue, making it denser. Women with denser breast tissue may have a higher risk of developing breast cancer because there are more cells that can become cancerous.
Dense breast tissue can also make a breast scan (mammogram) harder to read because it makes any lumps or areas of abnormal tissue harder to spot. Younger women tend to have denser breasts. As you get older, the amount of glandular tissue in your breasts decreases and is replaced by fat, so your breasts become less dense.
Overweight or obese
If you have been through the menopause and are overweight or obese, you may be more at risk of developing breast cancer. This is thought to be linked to the amount of estrogen in your body, as being overweight or obese after the menopause causes more estrogen to be produced.
Being tall
If you are taller than average, you are more likely to develop breast cancer than someone who is shorter than average. This may be due to interactions between genes, nutrition and hormones, but the reason is not fully understood.
Risk Factor of Breast cancer – Hormone replacement therapy (HRT)
Hormone replacement therapy (HRT) is associated with a slightly increased risk of developing breast cancer. Both combined HRT and estrogen-only HRT can increase your risk of developing breast cancer, although the risk is slightly higher if you take combined HRT.
It is estimated there will be an extra 19 cases of breast cancer for every 1,000 women taking combined HRT for 10 years. The risk continues to increase slightly the longer you take HRT, but returns to normal once you stop taking it.
Finally because of the many addictive risk factors you can seek help from AWAREmed Health and Wellness Resource Center under Doctor Akoury’s care where focus is on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE
Risk Factors of Breast cancer – Role of alcohol
