Dopamine effects and addiction

June 22, 2017

Dopamine effects and addiction are very active in the brain malfunctions

Dopamine effects and addiction: The brain

Dopamine is an inhibitory neurotransmitter, meaning that when it finds its way to its receptor sites, it blocks the tendency of that neuron to fire. We have noted that it’s associated with reward mechanisms in the brain. That aside, speaking to doctor Dalal Akoury MD, President, and founder of AWAREmed health center, new research on the brain is showing that addiction is a matter of memories, and recovery is a slow process in which the influence of those memories is diminished. That notwithstanding, further studies have also shown that addictive drugs stimulate a reward circuit in the brain. The circuit provides incentives for action by registering the value of important experiences. Rewarding experiences trigger the release of the brain chemical dopamine effects, telling the brain “do it again.” What makes permanent recovery difficult is the drug-induced change that creates lasting memories linking the drug to a pleasurable reward.

Dopamine effects and addiction: Brain circuits

Addiction involves many of the same brain circuits that govern learning and memory. Long-term memories are formed by the activity of brain substances called transcription factors. All perceived rewards, including drugs, increase the concentration of transcription factors. So repeatedly taking drugs can change the brain cells and make the memory of the pleasurable effects very strong. Even after transcription factor levels return to normal, addicts may remain hypersensitive to the drug and the cues that predict its presence. This can heighten the risk of relapse in addicts long after they stop taking the drug.

Knowing more about how addiction works in the brain has not yet given us any effective new treatments, but it has suggested new possibilities while providing a better understanding of how the available treatments work. The hardest job will be finding substances that lower the risk of addiction but do not interfere with responses to natural rewards. So far there is little evidence that any one type of therapy works better for addiction than another.

Dopamine effects and addiction: Brain Chemistry

It has been demonstrated times and again that drug addiction is a powerful force that can take control of the lives of users. In the past, addiction was thought to be a weakness of character or just misbehavior, but in recent decades research has increasingly found that addiction to drugs like cocaine, heroin, and methamphetamine is a matter of brain chemistry.

Experts at the National Institute on Drug Abuse, says that the way a brain becomes addicted to a drug is related to how a drug increases levels of the naturally-occurring neurotransmitter dopamine, which modulates the brain’s ability to perceive reward reinforcement. The pleasure sensation that the brain gets when dopamine levels are elevated creates the motivation for us to proactively perform actions that are indispensable to our survival for example eating or procreation. Dopamine is what conditions us to do the things we need to do. Having understood the power of addiction and what it can do to your health, it would be unwise to let drugs bring you down because of ignorance. Doctor Dalal Akoury founded this facility to help you have your life back and live it to the fullest. Waste no time and schedule an appointment with today for the commencement of your recovery process.

Dopamine effects and addiction: The brain

How-Drug-Addiction-Affects-Serotonin-And-Dopamine

Dopamine reward principal

April 4, 2017

Dopamine reward principal. In fact, all addictive drugs and activities release varying amounts of dopamine into the nucleus accumbens with stimulant drugs like cocaine and methamphetamine releasing the most

Dopamine reward principal: Mesolimbic pathway

When the brain’s reward center is activated, it releases dopamine which then creating a pleasing, enjoyable sensation primarily to motivate individuals into repeating these behaviors necessary for survival. The reason why this is happening is because dopamine has rewarded us with a pleasurable feeling. That in itself is a testimony that dopamine reward principle (master) is the fueling the human survival. With that understanding of the purpose and functioning of the brain’s reward system. It would be important that we interrogate its (dopamine reward master) functions a little bit further.

Dopamine reward principal: Ventral tegmental area (VTA)

The circuit most associated with pleasure and reward is the mesolimbic pathway which is located in the brainstem. The objective of this area of the brain is primarily concerned with basic survival. Within the mesolimbic pathway is an area called the ventral tegmental area (VTA). The VTA projects to the nucleus accumbens (thought to be the reward center). The neurotransmitter most commonly linked with the mesolimbic system is dopamine. Many people consider dopamine to be the driving force behind the human pursuit of pleasure. The release of dopamine is a pleasurable sensation. The release of dopamine motivates us to repeat behaviors or activities that prompted this release. This system’s purpose was to promote survival by rewarding life-sustaining behaviors such eating and procreation.

Dopamine reward principal: Nucleus accumbens

All addictive drugs and activities release varying amounts of dopamine into the nucleus accumbens with stimulant drugs like cocaine and methamphetamine releasing the most. However, when it comes to drugs like alcohol or heroin, the brain’s own opiate system (endorphins) also gets involved. Doctor Akoury MD and founder of AWAREmed Health and Wellness Resource Center reiterates that even though different forms of addictions have different effects in the nucleus accumbens, they share one common denominator, that is, they all activate the reward system which in turn motivates us to repeat those behaviors, even though they may be harmful. Besides what we have discussed about the concepts of reward, pleasure, and craving together, it is however very important to appreciate that there is a distinction between pleasure-seeking and drug seeking. Note that pleasure-seeking is all about the pleasurable, rewarding aspect of addiction while drug-seeking refer to the craving aspect of addiction. Dopamine may be more involved in drug-seeking (craving) component of addiction. The opiate (endorphin), GABA, or glutamatergic systems may be more involved in a pleasure-seeking aspect of addiction too.

Finally, pleasure-seeking and drug-seeking (cravings) are interrelated, yet distinct. Research has established that natural rewards (food, water, sex) typically lessen their influence on the reward system over time. As a behavior occurs more often, dopamine levels tend to decrease in the process. Psychologists call this habituation. This makes sense. Once you’ve eaten enough food, you don’t need to be rewarded for eating more food. Then you would be eating too much, or too much of one type of food. Therefore everyone needs to take heed of keeping the brain free from all attacks be it from substances or otherwise. Talking to the experts at AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury should be your starting point. Call us today to schedule that very important appointment today for the commencement of your journey to full recovery from your addiction.

Dopamine reward principal: Mesolimbic pathway

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Dopamines on drug addiction effects

December 27, 2016

Dopamines on drug addiction effects and in fact dopamine levels variance and dopamine reward master. The neurotransmission and substance abuse needs immediate treatment

Dopamines on drug addiction effects: Drug addiction and the brain

Dopamine is an inhibitory neurotransmitter, meaning that when it finds its way to its receptor sites, it blocks the tendency of that neuron to fire. We have also noted previously that it is strongly associated with reward mechanisms in the brain. That aside, speaking to doctor Dalal Akoury MD, President, and founder of AWAREmed health center, new research on the brain is showing that addiction is a matter of memories, and recovery is a slow process in which the influence of those memories is diminished. That notwithstanding, further studies have also shown that addictive drugs stimulate a reward circuit in the brain. The circuit provides incentives for action by registering the value of important experiences. Rewarding experiences trigger the release of the brain chemical dopamine, telling the brain “do it again.” What makes permanent recovery difficult is the drug-induced change that creates lasting memories linking the drug to a pleasurable reward.

Dopamines on drug addiction effects: Brain circuits

Addiction involves many of the same brain circuits that govern learning and memory. Long-term memories are formed by the activity of brain substances called transcription factors. All perceived rewards, including drugs, increase the concentration of transcription factors. So repeatedly taking drugs can change the brain cells and make the memory of the pleasurable effects very strong. Even after transcription factor levels return to normal, addicts may remain hypersensitive to the drug and the cues that predict its presence. This can heighten the risk of relapse in addicts long after they stop taking the drug.

Knowing more about how addiction works in the brain has not yet given us any effective new treatments, but it has suggested new possibilities while providing a better understanding of how the available treatments work. The hardest job will be finding substances that lower the risk of addiction but do not interfere with responses to natural rewards. So far there is little evidence that any one type of therapy works better for addiction than another.

Dopamines on drug addiction effects: Brain Chemistry

It has been demonstrated times and again that drug addiction is a powerful force that can take control of the lives of users. In the past, addiction was thought to be a weakness of character or just misbehavior, but in recent decades research has increasingly found that addiction to drugs like cocaine, heroin, and methamphetamine is a matter of brain chemistry.

Experts at the National Institute on Drug Abuse, says that the way a brain becomes addicted to a drug is related to how a drug increases levels of the naturally-occurring neurotransmitter dopamine, which modulates the brain’s ability to perceive reward reinforcement. The pleasure sensation that the brain gets when dopamine levels are elevated creates the motivation for us to proactively perform actions that are indispensable to our survival for example eating or procreation. Dopamine is what conditions us to do the things we need to do. Having understood the power of addiction and what it can do to your health, it would be unwise to let drugs bring you down because of ignorance. Doctor Dalal Akoury founded this facility to help you have your life back and live it to the fullest. Waste no time and schedule an appointment with today for the commencement of your recovery process.

Dopamines on drug addiction effects: Drug addiction and the brain

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Dopamine levels variance and the feelings of satisfaction

October 10, 2016

Dopamine levels variance and dopamine reward master. The neurotransmision and substance abuse needs immediate treatment

Dopamine levels variance: Neurotransmitter role in drug addiction

This is may be due to genetics, environment related or a combination of factors. A study concluded that pathological gamblers most often experienced traumatizing experiences when they were younger. Since most people who became addicted to gambling have low dopamine levels, and also that same group usually has endured a traumatic experience, it was concluded the overall dopamine levels can change due to environmental factors. This supports the opinion that both the mind and the brain can change due to environmental factors. However in yet another study it was established that a gene related to dopamine is sported twice as often in pathological gamblers than non-gamblers. To this effect, doctor Akoury says that this view seems to supports the observation that dopamine levels are genetic. We can therefore come up with two possible observations. Either both genetics and environmental factors affects ones brain anatomy and mind simultaneously, or that environmental factors can affect genes which in turn affect ones brain and mind.

Dopamine levels variance: Why is risk and reward a trigger for the release of dopamine?

It’s scientifically logical that sex and food release dopamine, because they are essential for the life of human beings. Risk and reward are not. It is believed that everything happens for a reason; meaning, there must be a scientific explanation for the increase of dopamine levels as a result of risk and reward. Like for instance the human race is different from other species on this planet not only by its ability to reason, but also its ability to create and be innovative. Therefore nature dictates that humans are creative and innovative, and for this to happen a person should have some level of satisfaction when one accomplishes an innovation. Doctor Akoury agrees that for one to accomplish an innovation he/she must take certain risks. It is risky to try to do something that no other being on earth has ever accomplished. Therefore, there must be a reward other than material that one gets when he or she accomplishes the innovation, otherwise that person would not take the risk. The reward here is the release of dopamine and the feeling of satisfaction. The problem with this process is that not only can one be satisfied after a major risk and accomplishment, but that one can also be satisfied through constant minute risks and accomplishments.

The feeling of satisfaction that dopamine exhibits are so strong that one can often lose his or her ability to reason in order to achieve satisfaction. It is that unconscious state of mind that takes over and begins to make certain decisions. The brain develops neural circuits that unconsciously assess reward. Since dopamine plays an active role in these circuits, people will act in what they think is in their best interest, when in fact the only interest it satisfies is the release of dopamine. This can be exemplified in gambling where one insists on gambling even though he or she knows that the odds are against them. Finally we appreciate that there is a lot of scientific explanations in this topic which may not be very clear to many people and if you are one of them then we are more than ready at AWAREmed Health and Wellness Resource Center to listen and help you be on the know. All you have to do is to call doctor Dalal Akoury (MD) who is also the founder of the facility for an appointment and all your concerns will be addressed professionally.

Dopamine levels variance: Neurotransmitter role in drug addiction

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Dopamine reward master and drug seeking basics

July 30, 2016

Dopamine reward master and drug seeking basics. The neurotransmission and substance abuse needs immediate treatment

Dopamine reward master and drug seeking basics: Mesolimbic pathway

While we were looking at the dopamine influence in substance abuse, it became quite clear that when the brain’s reward center is activated, it releases dopamine which then creates a pleasing, enjoyable sensation primarily to motivate us into repeating these behaviors which are necessary for our survival. The reason why this is happening is because dopamine has rewarded us with a pleasurable feeling. That in itself is a testimony that dopamine reward master is the fueling the human survival. With that understanding of the purpose and functioning of the brains reward system. It would be important that we interrogate its (dopamine reward master) functions a little bit further.

Dopamine reward master and drug seeking basics: Ventral tegmental area (VTA)

The circuit most associated with pleasure and reward is the mesolimbic pathway which is located in the brainstem. The objective of this area of the brain is primarily concerned with basic survival. Within the mesolimbic pathway is an area called the ventral tegmental area (VTA). The VTA projects to the nucleus accumbens (thought to be the reward center). The neurotransmitter most commonly linked with the mesolimbic system is dopamine. Many people consider dopamine to be the driving force behind the human pursuit of pleasure. The release of dopamine is a pleasurable sensation. The release of dopamine motivates us to repeat behaviors or activities that prompted this release. This system’s purpose was to promote survival by rewarding life sustaining behaviors such eating and procreation.

Dopamine reward master and drug seeking basics: Nucleus accumbens

All addictive drugs and activities release varying amounts of dopamine into the nucleus accumbens with stimulant drugs like cocaine and methamphetamine releasing the most. However when it comes to drugs like alcohol or heroin, the brain’s own opiate system (endorphins) also gets involved. Doctor Akoury MD and founder of AWAREmed Health and Wellness Resource Center reiterates that even though different forms of addictions have different effects in the nucleus accumbens, they share one common denominator, that is, they all activate the reward system which in turn motivates us to repeat those behaviors, even though they may be harmful. Besides what we have discussed about the concepts of reward, pleasure, and craving together, it is however very important to appreciate that there is a distinction between pleasure-seeking and drug seeking. Note that pleasure-seeking is all about the pleasurable, rewarding aspect of addiction while drug-seeking refer to the craving aspect of addiction. Dopamine may be more involved in drug-seeking (craving) component of addiction. The opiate (endorphin), GABA, or glutamatergic systems may be more involved in pleasure-seeking aspect of addiction too.

Finally pleasure-seeking and drug-seeking (cravings) are inter-related, yet distinct. Research has established that natural rewards (food, water, sex) typically lessen their influence on the reward system over time. As a behavior occurs more often, dopamine levels tend to decrease in the process. Psychologists call this habituation. This makes sense. Once you’ve eaten enough food, you don’t need to be rewarded for eating more food. Then you would be eating too much, or too much of one type of food. Therefore everyone needs to take heed of keeping the brain free from all attacks be it from substances or otherwise. Talking to the experts at AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury should be your starting point. Call us today to schedule that very important appointment today for the commencement of your journey to full recovery from your addiction.

Dopamine reward master and drug seeking basics: Mesolimbic pathway

http://www.awaremednetwork.com/

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