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How To Test For Male Infertility

Male Fertility Testing

microdeletion-analysisIn many couples, getting a baby is a dream come true. Getting pregnant is not always effortless and may require medical assistance. Finding the causes of infertility is the first step. In about half the cases of couple infertility, the man may have reproductive issues. It is not that serious usually with very few cases being diagnosed as sterile. That said, man can expect to go through one of the following tests with tests getting more serious with each one: sperm and semem analysis, hormone assessment or genetic testing. It is pretty invasive both physically and emotionally.  To whether the storm it is recommended you actually share past history with your partner before it is pried out into the open.

Physical examination

A physician will do a full physical examination. They will be looking at the testes, penis and other connecting organs for wholeness and good health. All body systems will be observed for general health and signs of disease. After a physical examination, one gets a chance to give a detailed medical history.

  • Non-medical diagnosis

A detailed and frank discussion on sexual history will need to be taken. Whether alone or as a couple, there needs to be a complete itinerary on sexual partners and experiences. Any incidents and accidents for example venereal diseases, late adolescence, premature ejaculation are up for discussion. This will help the doctor identify sexual history and risk factors.

In this discussion, there will be a section on lifestyle issues. Lifestyle factors like diet, exercise, illicit drug use, smoking, stress etc. need to be revealed to appropriately diagnose the cause of infertility. Any lifestyle issues stressing the body’s reproductive systems can be identified from this simple test. It might be a bright idea to have your partner complete a similar questionnaire on the man’s lifestyle as sometimes there is a bias towards underestimating the damage we do to our bodies.

Next up will be discussion on medical and reproductive health.  All major diseases like cancers, polio, surgeries, untreated illness and long term symptoms (e.g. migraines) will have to be revealed. Next up will be a revelation of any long term medications and any hereditary diseases.

  • Sperm and semen analysis

To conduct a thorough sperm and semen analysis, a fresh sample should be given to the testers. Ideally the subject should have a full load with no sexual interaction 72 hours before the test but no longer than a week as it can alter the results of the test. The sample should also not get to the lab as soon as possible, ideally no longer than 4 hours after ejaculation.

The test will be done to determine the quality and amount of semen a man produces in one ejaculate. Normal semen comes out as a thick gel becoming less viscous and finally turning liquid after 20 minutes. The pH also needs to be optimal for sperm survival. Fructose feeds sperm during their journey. High fructose levels are therefore needed for successful conception. Examination of the number of sperm per mililitre will be conducted. Sperm needs to be normally shaped with complete genetic information for successful conception. The sperm also need to have motility – that is, in most of the sperm need to be moving forward. There also needs to be an adequate number of sperm in the ejaculate.

In the most direct way possible, a sperm and semen analysis is the most direct of the fertility tests as it analyses the  viability of conception.

Men’s fertility is mainly stimulated by the hormone testosterone. The androgen is mainly produced in the testicles with adrenal glands creating a supplementary role. Testersterone causes the body to make sperm. When it is low, the pituitary glands create a luteinizing hormone signaling the testicles to compensate. This feedback loop is very important for the balance of hormones and continued fertility. When testing for fertility, one may find that there is either a predominance of testosterone or luteinizing hormone

Hormonal testing is important to find out if there are any background issues in suspected infertility and whether it is temporary, or has existed for a while. It will find reveal whether other organs in the endocrine systems are functioning optimally. The woman would benefit from a similar test for the same reasons.

Fertility_Score

Genetic testing

This is often the last test if other tests and investigations have not revealed a cause of infertility. Approximately 15% of couples who experience infertility have genetic issues. It is especially recommended for older couples and people with hereditary conditions. A family history with Down ’s syndrome, sickle cell disease, Alzheimer’s disease may choose to have more information on their genes. Any children borne to the couple stand a chance of exhibiting any of the hereditary diseases.

A blood sample is taken to analyze chromosomal material. The chromosomes in DNA determine sex characteristics and in an indirect way fertility. They come in pairs for example XX or XY. On occasion, there are abnormalities in the set-up and structure of the sequence causing trouble. The individual may be missing or have extra copies of the ‘sex’ chromosomes. A malfunctioning Y chromosome could affect the normal production of sperm. There might also be a problem with the internal structure of the chromosomes themselves, resulting in an untenable pregnancy. Some mutations of cystic fibrosis have been known to affect the reproductive capability of the carrier. It is therefore necessary to have that test done as well to rule it out.

In conclusion, diagnosing male infertility requires a detective work and elimination of possible factors. It can also take a long time, straining the stamina and resolve in a couple. Counselling throughout the process may do much good in strengthening the couple and preparing them in the eventuality of sterility.

Male Fertility Testing

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How To Re-Energize The Mitochondria By Use Of Intravenous Therapy

How To Re-Energize The Mitochondria By Use Of Intravenous Therapy To Prepare For Easy Addiction Detoxification

Intravenous TherapyDamages and the dysfunctions in mitochondria is an important factor in a range of human diseases due to their influence in cell metabolism. Mitochondrial disorders often manifest in a number of ways such as neurological disorders, diabetes and endocrinopathy.

In other diseases, defects occur in nuclear genes leading to dysfunctions of the mitochondrial proteins. Diseases such as hereditary spastic paraplegia, Friedreich’ ataxia and Wilson’s disease also result because of this. These diseases are inherited as in the case to other genetic diseases.

Mitochondria are central to oxidative phosphorylation and plenty of metabolism in the body and are also involved in plenty of cell deaths. Mitochondrial dysfunction therefore contributes to a wide range of human illnesses. Many patients with disease of the mitochondria also have issues with their gastro-intestinal tract and this is treated by therapies through nutritional intake. Such like patients usually have weak immune systems and as such they are always in constant battle with numerous infections. History and research reveals that earlier intravenous nutrition consisted of protein and dextrose alone. Lipids were then later introduced and later removed due to complications, but this was later re-introduced again.

At the moment or rather current time, there are multiple options in intravenous therapy for nutrition. The pump options are such as Gemstar and even CADD. Obtaining nutrients orally or through the gastro-intestinal is usually the most effective, since this is always a more physiological process.

However, if this is not possible, the intravenous nutrition is done, in the form of intravenous hydration or through home parenteral nutrition. Parenteral nutrition involves providing the patient’s calories using an intravenous line that leads into the central circulatory system. Intravenous nutrition involves giving fluids and can be used as a medium of providing electrolytes and other additives.

Various factors are important in determining the kind of hydration that is ideal for a patient. The length of time the procedure takes as well as how and where the hydration happens are most often the main factors to consider.

Hydration is a major issue with people suffering from mitochondrial disease. For one to decide to start intravenous hydration he should keep in mind whether the treatment is long-term or for a short term. The kind of lines through which intravenous hydration is done are peripheral, PICC line, PortACath and tunnel catheters.

Peripheral is placing the intravenous lines in the hand or arm and for a short period of time, normally between three to five days. This method is not ideal for use at home because it requires a professional to do it and fewer nurses have such kind of professional training.

MitochondriaPICC is placed with the aid of an X-ray in the upper arm where the catheter goes directly into the central circulatory system. The site or area of insertion should be protected from infections by always keeping it dry.

PortACath is usually placed in the upper chest of the patient.in this type of line, the needle can be removed and the patient is allowed to swim or even shower.

Tunnel catheters are also usually in the upper chest and surgically removed .however, they can also be placed somewhere hidden. There is a risk of infection with this type of intravenous hydration.

Many patients are allergic to the substances involved and suffer from skin breakdown and are therefore more susceptible to infections. Also because of lower immunity, they are prone to infections. Furthermore, these patients also stand a higher risk of clotting. These treatment lines should be handled with care and fewer people. They should be thoroughly washed and items cleaned separately. The access points should be sanitized with alcohol prior to injection.

Some complications such as catheter occlusion caused by blood clotting occur, due to thrombotic clots. But there are medications that clear clots on the catheter.

Infections are normally common because of a component in blood that encourages growth of bacteria. This component is known as biofilm. The biggest threat to intravenous nutrition however is catheter related blood stream infections. This is treated by antibiotics, antibiotic locks and by changing of the central line.

Intravenous therapy is also a great way to get a high dose of vitamins, vital minerals and antioxidants into the circulatory system. Therefore, the nutrients are quickly introduced into the circulation and are delivered directly into the cellular space without having to go through the gastro-intestinal tract.

Many people notice improved immunity, higher energy levels and enhanced detoxification through therapies.

Intra venous nutrient therapy also provides higher doses as   compared to oral therapy.

Scientists have been studying the effects of higher doses of Vitamin C for quite a long time.

Vitamin C is essential as a water-soluble vitamin that is commonly also known as ascorbic acid.  The antioxidant effects of Vitamin C have been researched extensively to show positive and protective benefits against many ailments.

Myer’s Cocktail, AMP/NAD Energy Shots and MSM Infusions can also be used to boost the mitochondria

One may just feel a cold or a viral illness is coming on but once you have an intravenous cocktail that may well restore your health.

Whether you need help on balancing adrenals or you are an addict who is looking for a natural way of gradually recovering from an addiction, Awaremed Resource And Wellness Center is your perfect solution. You are free to call us, for more go to www.awaremednetwork.com

How To Re-Energize The Mitochondria By Use Of Intravenous Therapy To Prepare For Easy Addiction Detoxification

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Gene Therapy, Epigenetic Gene Therapy

Gene Therapy Is an Effective Cancer Treatment Alternative

Gene TherapyCancer has continued to threaten the very existence of the human race. Being a disease with numerous causes, it has become so hard to evade it completely. This has led to doctors trying to find the best ways of curbing it or better yet do away with it completely. Researchers have given foundations upon which these alternative cancer treatments can be based. The researchers have even studied and known the cancer cell survival mechanisms and this has led to emergency of very many alternatives that all affect the cancer cell survival in a way. Just like farmers know-the best way to do away with a weed is to uproot it completely as it will not grow again lest another seed is planted. The best way to treat cancer is to find a way of doing away with it from the roots. Unfortunately most of the cancer treatments that our loved ones are subjected to are only focused on killing the cancer cell and reducing the severity of the symptoms. This is why there are cases of repeated chemotherapies that instead of helping in killing the cancerous cells only make the cancerous cells more resistant to the drugs. Our environments expose us to myriads of carcinogens that affect the DNA make up of our body cells. There are very dangerous heavy metals that will make us prone to cancer when we interact with them consistently and this is a problem that has been facing industrial workers over the years. Upon intrusion into the body they are likely to affect our DNA make up resulting in gene mutation which is synonymous to cancer. Genes play an important role in cancer treatment and so therapies that target the gene may go a long way in healing the cancer patients, that is Gene Therap

Changes that take place in a gene are most likely to cause cancer .these changes that take place in a gene that increases cancer risk may happen due to exposure to environmental carcinogens like smoking tobacco and other potential gene mutants that emanate from the surrounding. However a person may inherit faulty genes from the parents making him have a higher risk of getting cancer. A person may inherit faulty genes from the parent but if he adopts a healthy lifestyle and evade all the potential gene mutants then he may not get the disease.

What is gene therapy?

Cancer being caused by gene mutations it is better to have a way of treating the cancer by repairing the faulty genes or better yet replacing them with functional genes so that the routine gene functions are revived. Gene therapy is a way of repairing genetic problems. This can be achieved by adding a functional copy of the defective gene. When a functional copy of a faulty gene is added, the tissues  and organs that might have been affected by the gene mutations will begin to function in the right way. The gene therapy works better because unlike other cancer treatments that only treat the symptoms it goes deeper correcting all the genetic problems.

In cancer treatment most commonly, gene therapy uses a vector, typically a virus, to deliver a gene to the mutated cells where it’s needed to enable proper functions of the cell. Once its inside, the cell’s gene-reading machinery uses the information in the gene to build RNA and protein molecules. The proteins (or RNA) can then carry out their job in the cells. When the normal functioning of the genes is achieved the cancer cell duplication is inhibited and this is a better strategy in cancer treatment.

Scientists are still developing several gene-therapies that will be very helpful in cancer treatment. One of the best therapies so far discovered is the use of a modified version of herpes simplex 1 virus. Herpes simplex 1 virus is known to cause cold sores yet it has been found to have the ability to effectively fight cancer especially the cancer of the skin (melanoma) that has spread in the body.

To make the use of herpes simplex 1 virus safer, the doctors will modify the virus in such a way that it will not cause the cold sores that it is known for. This treatment is referred to T- VEC. This treatment is also safer than other conventional cancer treatments as it does not affect the healthy body cells but is very effective in destroying the cancer cells. It stimulates the immune system enabling it to spot the cancer cells present in the body and fighting them. When the virus is injected into the tumor it produces more of itself by replication inside the tumor until they burst thereby producing even more of them that can infect many more cancer cells.

Gene TherapyIn a trial to show the effectiveness of the gene therapy, 59 patients suffering from the cancer of the blood had their immune systems cells removed and treated with a virus that genetically altered their genetic structure in order to spot the proteins that covers the surfaces of the cancer cells. The immune cells were then returned into the patient’s body. More than half of the patients experienced complete remission giving proof to the strength of the gene therapy in cancer treatment.

Dr. Dalal Akoury (MD) is an experienced integrative cancer doctor that has helped many cancer patients in their fight against the disease. She has worked hard not only in treating the disease but also in availing informational support to cancer patients at Awaremed which has become a place called home for many cancer patients. Call on her now and get help on cancer.

Gene Therapy Is an Effective Cancer Treatment Alternative

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Targeting Cancer Stem Cells in Treatment

Fighting Cancer Stem Cells Is Key In Effective Cancer Treatment

Cancer Stem CellThe rapid uncontrolled growth and duplication of cells is what leads to cancer. The rapid and uncontrolled division of cells is caused by mutations in the DNA that inhibit the vital functions of natural tumor suppressors while signaling some genes to hasten cell division. Currently in the entire world cancer is among the most feared diseases that are causing millions of people to lose their lives earlier than they should. In the United Kingdom alone, about 275,000 are diagnosed with cancer every year and about 150,000 of this people die. Most of these patients die after attempting many cancer treatments both conventional and other new alternative cancer treatments. Evidently they die because the treatments they opt for are not effective enough to treat this disease. Most of these treatments focus on killing the cancer cells which may only help in extending the lives of the cancer patients but do nothing to treat the patient. Some of the cancer treatments that focus on cancer cells may relieve the patients of the symptoms of the disease and assume treatment within sometimes but the disease will re-occur since the disease is not targeted from the roots. Most of these treatments will control cancer by inhibiting the growth of cancer cells or killing the cancer cells, other treatments may combine both approaches in fighting cancer. These treatments will work in cancer treatments but unfortunately the disease will re-occur. Therefore it is crucial to understand why this disease may re-occur after ‘successful’ treatment so that alternative therapies can be used to completely do away with this disease in the patients.

Cancer often reoccurs after treatment because in a tumor there are very many different cancer cells that might not be destroyed by the treatment. A treatment may target a certain type of cancer cell while the other cells are not targeted. This many lead to the other untargeted cells to grow and divide.

Normal Stem cells are able to renew and regenerate damaged tissues. New research shows that cancer cells may originate from the normal stem cells. Basically just like the normal stem cells the cancer stem cells are able to self renew and duplicate. The stem cancer theory proposes that within the tumors there are some cancer cells that act as stem cells that duplicate themselves rapidly hence sustaining the tumor just like the normal stem cells normally regenerate worn out tissues and renew the health of our organs. This view on cancer cell survival mechanisms shows that cancer cells may attack our bodies but may not be able to sustain the tumor for a long time therefore it is the cancer stem cells that are much of a problem in cancer treatment.

The discovery of the crucial role that cancer stem cells play in the growth and spread of cancer helps a great deal. This helps us realize that using the cancer treatments methods that only focus on the killing and shrinking of tumors may not help in the long run if the cancer stem cells are not targeted and destroyed. It is often quite unfortunate that cancer cells that are reoccurring row with such a resistance to chemotherapy drugs. Therefore cancer therapies that are only evaluated on their abilities to kill cancerous cells and shrink the tumors should be encourage for use if the patients needs to be cancer free – which I guess all cancer patients hopes for. As I have always said farmers may know this better than doctors. The best way to do away with a weed is to uproot it from the ground leaving no root in the soil. However low a weed is cut, if a single root is left in the soil then it will grow again. So treating cancer effectively will only be achieved by doing away with the cancer stem cells. Cancer stem cells are also very important in cancer metastasis hence should be targeted for a more affective cancer treatment.

Foods that inhibit growth of cancer stem cells

Nutrition plays a major role in controlling the growth of cancer cells in our bodies. The foods you eat will either put you at risk of cancer or help you even stay safer from the disease. Cancer stem cells play a great role in tumor growth and metastasis and therefore foods that inhibit the growth of cancer stem cells to be on the safer side. Researchers have done much to avail us best foods that can help us evade the risk of cancer. Most of these foods are nature given and are rich in cancer fighting properties. Here are three dietary compounds that inhibit growth of cancer stem cells.

v  piperine found in black  pepper

v  Curcumin found in turmeric.

v  Sulforaphane found in broccoli and broccoli sprouts.

Cancer Stem CellThese three dietary components have been proved to inhibit the growth of cancer stem cells by interfering with their signaling pathways.  The cancer stem cell pathways have been studied by scientists especially on the ability of these cancer stem cells to renew themselves and these pathways are evident in most types of cancers therefore the use of these dietary compounds that inhibit the functions of these pathways will help in treatment of all cancers.

Dr. Dalal Akoury (MD) is an experienced integrative cancer doctor that has helped many cancer patients in their fight against the disease. She has worked hard not only in treating the disease but also in availing informational support to cancer patients at Awaremed which has become a place called home for many cancer patients. Call on her now and get help on cancer.

Fighting Cancer Stem Cells Is Key In Effective Cancer Treatment

 

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Giving Your Mitochondrial Health a boost by IV NAD

Restoring Mitochondrial Health by IV NAD

What are mitochondria?

They are membrane bound organelles which are found in most of the cells (eukaryotic cells) that make up living things. They are also sometimes termed to as the powerhouses.

Why are mitochondria vital in our bodies?

Mitochondrial HealthAs we have just mentioned, mitochondria are also referred to as powerhouse due to the functions that they do in our bodies. Their main work is to generate the energy that our body cells require in order to execute their jobs. One of such cells which need a lot of energy is the brain cells. The brain cells are responsible for the communication to all the other parts of the body and thus these mitochondria must be transported along the cells.

Mitochondria generate chemical energy similarly to the one we normally get from batteries. This energy which is generated by the mitochondria in the form of chemical is referred to as Adenosine Triphosphate or simply ATP. This is an energy currency that every ling thing cell can use and this is what makes it possible for us to be kept alive.

What are mitochondrial diseases?

These are diseases which result from the failure of mitochondria. As we already know, mitochondria are responsible for supplying energy to the cells. Mitochondria themselves are present in all the cells except in the red blood cells. They produce about 90 of the energy that the cells use. In the case when the mitochondria fails to work, then the energy that the cells get decline and consequently cell injury or even cell death follow. If the process occurs all over the body, then the whole system fails and the life of the person in which it is happening becomes threatened.

These mitochondrial diseases commonly cause damage on critical organs such as the brain, heart, skeletal muscles, kidney and sometimes the respiratory system.

Symptoms of a mitochondrial disease watch out for

The symptoms of a mitochondrial disease vary depending with the cells that are affected. Generally they may include the following:-

  • There may be loss in motor control
  • Muscle weakness and pain may also be another symptom
  • Visual or hearing impairment, especially if their system cells are the ones affected.
  • Gastro-intestinal disorders & Swallowing difficulties may be evident when the respiratory cells are affected.
  • Another symptom of mitochondrial disease is poor growth, since for growth to occur, cell multiplication must occur and it is a process that requires a lot of energy.
  • The victim may also become diabetic
  • Cardiac disease
  • Liver disease
  • Respiratory infection
  • Seizure among many other symptoms.

Which principle is used in mitochondrial restoration?

Mitochondrial HealthMitochondrial restoration is a natural process that seeks to restore the various body organs which have been previously cellularly affected to their normal working state. The mitochondrial restoration targets the organs that have been affected by the decline in energy supply and hence whose functional capacity has been also been affected and then restores its functional state.

Mitochondrial treatment involves measures that restore cells to their normal working condition by ensuring they get the energy necessary for them to function. These measures involve ensuring that there are sufficient mitochondria in the body and they are working correctly. Therefore, the treatment seeks to eliminate the cause of mitochondrial failure which had previously occurred.

Why is IV NAD preferred in mitochondrial restoration treatment?

What is NAD? NAD refers to Nicotinamide adenine Dinucleotide, which is a metabolic co-enzyme responsible for every aspect of life. There are basically two classes of these co-enzymes, digestive and metabolic enzymes. NAD treatment bases on the metabolic enzyme, as this enzymes are responsible for restructuring, repair and remodeling of the cells. The metabolic enzyme provide an advantage in that they operate in every cell, every organ and every cell. NAD is essential in the production of ATP, which is the basic energy molecule in our bodies.

Advantage of IV NAD therapy in mitochondrial health restoration

As we have seen, mitochondria are very important since they are responsible for the production of energy that the cells use. When the cells do not get enough energy due to failure in mitochondria, this is a death threatening disease since it may cause all the cells to fail in their function and consequently failure in the entire systems which may pose the patient to death.

If the situation of energy deficiency occurs as a result of mitochondrial failure, this situation needs to be addressed as soon as possible. Prescription can be given to the patient in response to the situation, but this method has limitations. Some of the medications that are administered to mitochondrial failure patient are known to be habit forming and may cause dependency. This makes the patient rely on the medication on daily life and in case of withdrawal; withdrawal symptoms and craving for the drugs may follow.

IV NAD therapy is a treatment that is natural and is based on the principle that, “body has ability to heal on itself as long as the necessary conditions are maintained.” This means that even after the therapy is administered to the patient, there cannot be addiction to the drug. Another advantage is that the therapy generally contributes to the well-being of a person by ensuring the mitochondria are working correctly as well as the NAD co-enzymes.

Restoring Mitochondrial Health by IV NAD

 

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