Applying Endocrine Therapy for Breast Cancer Treatment

March 2, 2015

Applying Endocrine Therapy for Breast Cancer Treatment: Not everyone is Eligible for Endocrine Therapy

Applying Endocrine Therapy for Breast Cancer Treatment is one of the best treatment methods available today.

The treatment of cancer is one that makes so many people to panic in fear. Owing to the dangers associated with this disease people are often very worried of the outcomes of the treatment even as they hope for the best. We enquired from the experts at AWAREmed Health and Wellness Resource Center and doctor Dalal Akoury shared with us very useful information about endocrine therapy as a treatment option. Doctor Akoury who is also the CEO of this facility says that in applying endocrine therapy for breast cancer treatment careful attention should be taken not to confuse the hormones. There are certain hormones that can attach to breast cancer cells and affect their ability to multiply. The purpose of endocrine therapy, formerly called hormone therapy, is to add, block, or remove hormones. Doctor Akoury continues that with breast cancer, the female hormones estrogen and progesterone can promote the growth of some breast cancer cells. Therefore in some patients, endocrine therapy is given to block the body’s naturally occurring estrogen to slow or stop the cancer’s growth. There are two types of hormone therapy for breast cancer.

Drugs that prevent estrogen and progesterone from promoting breast cancer cell growth.
Drugs or surgery to turn off the production of hormones from the ovaries.

Take note, not to be confused between the hormone therapies applicable in treating women with breast cancer to that hormone replacement therapy that is typically used by postmenopausal women.

Hormone therapy for cancer treatment also known as endocrine therapy stops hormones from getting to breast cancer cells.
Hormone therapy for postmenopausal women without cancer called which is known as hormone replacement therapy adds more hormones to your body to counter the effects of menopause.

Applying Endocrine Therapy for Breast Cancer Treatment: Who can Get Endocrine Therapy for Breast Cancer

As part of the diagnosis process, tests are done to determine if the breast cancer cells have estrogen or progesterone receptors. If so, that means that growth of the cancer can be stimulated with these hormones. If a cancer is found to have these receptors, endocrine therapy is recommended as part of the treatment plan.

Applying Endocrine Therapy for Breast Cancer Treatment: Hormone Therapy Drugs Used for Breast Cancer

We have several common hormone therapy drugs used for breast cancer and they may include the following:

Tamoxifen
Arimidex
Aromasin
Femara
Zoladex/Lupron
Megace

Applying Endocrine Therapy for Breast Cancer Treatment: Breast Cancer and Tamoxifen

This pill has been used for over three decades now in treating breast cancer. Originally it was first used in metastatic breast cancer (cancer that spread) because it decelerate the development of cancer cells in the body. Tamoxifen also decreases the chance that some early-stage breast cancers will recur in premenopausal or post-menopausal women and it can reduce the risk of cancer developing in the unaffected breast. Besides that, it may offer an alternative to watchful waiting or prophylactic (preventative) mastectomy for women at high risk for developing breast cancer.

Tamoxifen is a type of drug called a selective estrogen-receptor modulator (SERM). At the breast, it functions as an anti-estrogen. Estrogen promotes the growth of breast cancer cells. Tamoxifen blocks estrogen from attaching to estrogen receptors on these cells. By doing this, it is believed that the growth of the breast cancer cells will be halted. Tamoxifen can also be considered as an option for the following cases:

Treatment of ductal carcinoma in situ (DCIS) along with breast-sparing surgery or mastectomy.
Adjuvant treatment of lobular carcinoma in situ (LCIS) to reduce the risk of developing more advanced breast cancer.
Adjuvant treatment of breast cancer in men and women whose cancers are estrogen-receptor positive.
Treatment of recurrent and metastatic breast cancer.
To prevent breast cancer in women at high risk for developing the disease.

Even though Tamoxifen is useful in cancer treatment, it is not applicable to everyone. The following people should not use tamoxifen:

Pregnant women
Women planning to become pregnant
Men or women with a history of blood clots or stroke

If the three points describe you then before considering this treatment mode, you will need to talk to your doctor to see if tamoxifen is right for you. Nevertheless as for women, the side effects of tamoxifen are similar to some of the symptoms of menopause. Two of the most common side effects are hot flashes and vaginal discharge. Other tamoxifen side effects in women may include:

Vaginal dryness or itching
Irregular menstrual periods
Headache
Nausea or vomiting
Skin rash
Fatigue
Fluid retention or weight gain

While some of its side effects are similar to menopausal symptoms, tamoxifen does not trigger or cause menopause in women. It’s (Tamoxifen) side effects in men may include:

Headache
Nausea or vomiting
Skin rash
Sexual side effects including impotence or decrease in sexual interest

While applying endocrine therapy for breast cancer treatment the question that many would be asking would be, “are there some risks involve for those people taking tamoxifen for treatment?” this is a valid concern, doctor Dalal Akoury agrees. In her response she gives a resounding YES. Therefore the following are some of the known risks involved when taking tamoxifen:

Fertility – Tamoxifen may affect fertility, so it is important to use some form of barrier birth control while you are taking it. However, do not use oral contraceptives like the pill since they may change the effects of tamoxifen and affect the breast cancer. Tell your doctor right away if you think you may have become pregnant while taking this medication.
Increased blood clots – Women taking tamoxifen may have a slightly increased risk of developing blood clots in the lungs or large veins. This risk is increased in smokers.
Increased risk of stroke
Uterine cancer/sarcoma – Tamoxifen may increase a woman’s risk of developing uterine cancer (cancer of the lining of the uterus) or uterine sarcoma. However, this risk is very small and needs to be balanced against the significant benefits of taking tamoxifen for breast cancer.
Cataracts – Taking tamoxifen appears to put some women at increased risk for developing cataracts, a clouding of the lens inside the eye. People have also reported eye problems such as corneal scarring or retinal changes.
Medications – Tamoxifen may affect the metabolism of other drugs.

Applying Endocrine Therapy for Breast Cancer Treatment: Tamoxifen and Breast Cancer Prevention

Over the years efforts has been made by different researchers with an objective of establishing whether tamoxifen would reduce the occurrence of breast cancer in healthy women known to be at high risk. The outcome of the trials indicated a 50% reduction in both invasive and non-invasive breast cancer in the women treated with tamoxifen. Besides that, tamoxifen has also been shown to significantly reduce the risk of developing invasive breast cancer in women who have had ductal carcinoma in situ (DCIS). We may not be able to exhaust everything in this article and I want to introduce you to the expert for further consultation. You can schedule for an appointment with doctor Akoury for all the concerns you may have about applying endocrine therapy for breast cancer treatment.

Applying Endocrine Therapy for Breast Cancer Treatment: Not everyone is Eligible for Endocrine Therapy

Cancer the most feared Health condition

February 24, 2015

Cancer the most feared Health condition: After the Diagnosis

Cancer the most feared Health condition.Although signs vary among the different types of cancer, cancer symptoms can include pain, fatigue, and unexplained weight loss.

For a couple of weeks we will be posting articles torching on the information about cancer as a chronic health complication. The various kinds of cancers causes, signs and symptoms treatment and prevention. The articles are going to be very rich in information about cancer the most feared health condition across the globe. We want to lay down the foundation for this series and take this earliest opportunity to invite you to keep and invite other people into this link so that we can take precaution for all of us. A team of experts from AWAREmed Health and Wellness Resource Cancer are going to explaining to us certain complex information for a better understanding.

Many people however take the simplest meaning of cancer to suggest that it is the abnormal growth of cells somewhere in the body. As we ponder with that it is sad noting that every year more than a million people are diagnosed with a cancer condition and the most common types of cancer include:

Breast cancer
Prostate cancer
Lung cancer and
Colorectal cancer

Besides the three major types of cancer treatment surgery, chemotherapy, and radiation therapy experts are working to find new and more effective ways of fighting cancer. Prevention would be applicable for some cancers conditions while the other types can be avoided by adopting and practicing consistently a healthy lifestyle that is free from drugs. And like I had said before that after a cancer diagnosis has been done whether it’s your own or that of a loved one the right information can be one of your most powerful weapons in fighting this chronic health condition. Doctor Akoury shares with us some of the pertinent things and information everyone would need to know about cancer treatment and management.

Cancer the most feared Health condition: What Is Cancer?

It’s very important to begin by understanding what problem we are talking about. This is one of the word diagnosis that frightens and scary to most people. Everybody is at threat and therefore we can demystify cancer by getting certain facts right. Even though it is a world phenomenon more than one million people are diagnosed each year with cancer. Cancer strikes half of all men and one out of three women in the United States, and there are currently more than 12 million cancer survivors living in US. Cancer doesn’t discriminate in any way it can affect and infect anybody irrespective of your gender, color, status or ethnicity. Therefore to help demystify cancer, start by learning basic facts about it.

Cancer the most feared Health condition: Cancer Basics

Cancer is often feared and misunderstood, and there are many misconceptions about this disease. But education is the best defense, so don’t believe the common cancer myths that are being escalated around you. Although signs vary among the different types of cancer, cancer symptoms can include pain, fatigue, and unexplained weight loss. Doctor Akoury explains that cancer affects in stages and so depending on your cancer stage, you and your treatment team will come up with a cancer treatment plan that’s right and is applicable for you. You may also be interested in enrolling in a cancer clinical trial, which can offer access to newer and more experimental therapies.

Cancer the most feared Health condition: The Root of Cancer

This is one of the basic fundamentals that are very important to get right. Cells, which make up human tissue, form the basis of our organs. On the most basic level, cancer is the abnormal growth of some of our cells. The body is busy and is constantly renewing themselves. What that means is that we have cells that grow and divide. Remember that these cells usually have a finite life span and cancer as a disease process represents cells in our body that no longer respond to the usual growth and death signals. A cancer cell no longer responds to those signals and becomes immortal that is to say it doesn’t die. When that happens, the cell has the power to spread elsewhere in the body and grow in areas where that particular type of cell would not normally grow.

Cancer the most feared Health condition: Types of Cancer

Primarily different kinds of cancers derived their names from the organ experiencing the abnormal growth of cells, as with breast cancer and prostate cancer. Leukemia, a group of blood cancers, starts with the leukocytes; the type of white blood cells affected, and gets its name from them. For men, the most common type of cancer is prostate cancer. For women, it is breast cancer. After those gender-specific cancers, lung cancer and colorectal cancers are the next most common types for both men and women. Following these, the most prevalent types of cancer are split by sex again: bladder cancer and melanoma for men, and uterine cancer and non-Hodgkin lymphoma for women. That is ideally the trend that it takes when it come to the various kinds of cancers we have.

Cancer the most feared Health condition: Cancer Treatments

Like I had indicated before, there are three major types of cancer treatment most often used today and they include:

Surgery to remove the cancer
Radiation therapy, which uses energy to kill cancer cells
Chemotherapy, which uses drugs to kill cancer cells

Experts are constantly working to find new and more effective cancer treatment options. Cancer treatment is moving away from simply killing cancer cells and toward targeted therapies for cancer patients. This is a form of chemotherapy that interferes with the underlying mechanisms that make a cancer cell a cancer cell.

Cancer the most feared Health condition: Cancer Risk Factors

When I mentioned prevention as a remedy I meant it because it is much easier to prevent that to treat. Like for instance there are certain lifestyle behaviors, like smoking, a poor diet leading to overweight or obesity, and being sedentary which we can collectively or even individually avoid to be safe from the attacks of cancer. These are all cancer are some of the major risk factors however the other risk factors may include:

Other tobacco use, such as chewing tobacco
Too much sun exposure
Excessive alcohol consumption

It’s estimated that half of all cancer deaths could be prevented by some simple lifestyle changes. Look at some of these practices, don’t you think that it is possible to quitting smoking, eat a healthy diet that includes lots of plant-based foods, maintain a healthy body weight, and getting regular exercise? Imagine that by doing that you will be sending cancer away from your life if not from your generation.

Vaccines, antibiotics, and changing certain sexual behaviors could also prevent cancers that are linked to infectious diseases, like the human papillomavirus, hepatitis B virus, and HIV.

Finally as we lay this informative foundation we want to bring to your attention that doctor Akoury founded this medical facility (AWAREmed Health and Wellness Resource Center) to help the society understand the take the lead role in the prevention. We appreciate that cancer will probably always sound frightening at first, but understanding what it represents, how it can be treated, and what you can do to help reduce your risk of developing cancer can help bring it to manageable levels and that is our objective. We want to have you along so that together we put some of these diseases out of our societies. Talk to us if you have any concerns and we will be there to listen to you and attend to you professionally.

Cancer the most feared Health condition: After the Diagnosis

Effects of breast cancer on your beauty

February 9, 2015

Effects of breast cancer on your beauty: Why Radiation is the major problem?

Effects of breast cancer on your beauty can be very fatal if treatment is not done in good time.

When we talk of being beautiful all round it means that every part of your body is appealing. It also means that you have the emotional certification that you are internally beautiful. That is to say your self-esteem is super and consistent. The problem we have is often associated of keeping that beauty for a long time. It may be easy to initiate the process of being beautiful, but keeping that beauty may be challenging. In that respect, we want to explore for the purpose of this article, the effects of breast cancer on your beauty. Breast cancer is ideally one of the most fatal ailments threatening the lives of very many women. And to add salt into injury treatments for breast cancer also can affect your skin at times, leaving it unpleasantly dry or flaky and more sensitive to exposure to sun, wind, and other elements. To help us understand how cancer treatment can cause damage to your skin, doctor Dalal Akoury an expert in beauty care and also the founder of AWAREmed Health and Wellness Resource Center is sharing with us some insight to be weary of if we have to keep our skin glowing.

Effects of breast cancer on your beauty: Chemotherapy and skin care

The reason why we all need to be very concern with the chemotherapy treatment is because while the skin needs to be well hydrated, it frustrates skin hydration by reducing the amounts of oil produced by your glands. The solution to this would be using moisturizers more periodically. It is important that you use quality products to defend your skin from the effects of the sun by blocking UVA and UVB rays. In addition to these gentle moisturizing soaps particularly those of children are very good since they are mild and are deodorant free.

Effects of breast cancer on your beauty: Radiation and skin care

Radiation to the breast impacts negatively to the skin causing changes which really make you look bad and tattered. Therefore, the following are some of the effects which may be associated with radiation:

Irrespective of where you come from, tribe or otherwise, radiation will change your skin color. For example those who are light in color and dark in color will turn red and darker respectively. Even though the affected areas may be limited to some small patches, there can be some itching, burning, and tenderness of the skin. You may have some dry peeling, like old sunburn, as the skin rubs off.
If you are big-breasted, or if your doctor is treating the area after a mastectomy, there is a greater chance for “wet” peeling, like a blister. This is usually limited to specific spots.
The skin generally heals quickly and completely with the red reaction going away fastest. The change-over to tan shading, if you have light skin, can take a few weeks to go away. However in women of color, the darkening of the skin can be more significant and may also take longer to disappear.
Ordinary freckles and moles can become much darker within the treatment field. These spots are almost always benign, but they will darken because of the treatment. After you finish radiation, they usually return to their normal color, and some eventually disappear.

With all these complications, doctor Akoury says that there are very many products in the market which can help ease your way through treatment. The products may include aloe and aquaporin, which can be found in some drugstores and large convenience stores. And besides occasionally you may need to use some type of steroid cream, such as a 1% hydrocortisone cream. Some women also benefit from a prescription-strength steroid cream. Your physician will be able to advice if you need a referral to a dermatologist for more care.

Effects of breast cancer on your beauty: Radiation and sun

Skin that receives radiation treatment has an increased risk of developing skin cancer in the future. This is why it is so important to take extra precautions to protect the skin within the radiation treatment field from the sun. Take note that the part of the breast near your cleavage will probably be in the treatment field, and that’s also the area exposed to the sun when wearing a bathing suit or tank top. It is therefore advisable that you use a moisturizer or body lotion with sun protection factor (SPF) of at least 30.

Effects of breast cancer on your beauty: Skin and sun precautions

Excessive exposure to the sun is responsible for much of the skin damage associated with aging. It’s also the leading cause of skin cancer by far the most common form of cancer diagnosed today. Even though it may take up to 12 hours for you to see the effects of the sun burn, ordinarily it takes as little as 15minutes for the sun’s ultraviolet rays to harm the skin. In severe sunburns particularly during childhood and adolescence can increase the chances of developing the more serious form of skin cancer malignant melanoma later in life. However, it is important to note that the development of breast cancer does not necessarily make you vulnerable to the risk of contracting skin cancer.

Doctor Akoury says that because of these, you need to protect your skin every time you go outside irrespective of whether it is cloudy or not. Ensure that you only use those products rich in the proper SPF, or sun protection factor. While doing all these remember not to forget the treatment of your lips. The lips contain few oil and sweat glands and no melanin (a protective chemical in the rest of your skin). So they are not protected from moisture-robbing ultraviolet rays. Instead of using lip balms which contain camphor, menthol, or phenol, use products with moisture-sealing ingredients and SPF protection.

Effects of breast cancer on your beauty: What to do for healthy looking skin

Sleeping on your back is very helpful more so with your head elevated. This reduces the puffiness we often observe in the mirror each morning. You might want to invest in a buckwheat or form-fitting pillow that will help keep your head upright.
Smoking is definitely not advisable. The heat and smoke of the cigarette itself will constrict your blood vessels and cause wrinkles. And overuse of the muscles used to draw in the smoke can cause just as many wrinkles. Take note that tobacco smoking is a major risk factor for lung cancer.
Avoid applying products with alcohol content on your face. Such products will cause skin dehydration even for oily skin.
Don’t wash your face more than twice a day, unless you exercise. In that case, be sure to wash away any sweat that could be drying to your face as it evaporates. You might also consider a non-soap skin cleanser.
Remember that skin cleansing; exfoliation and moisturizing are all helpful in protecting the skin against the sun rays and other elements.

Finally cancer is not any kind of disease you can easily wish away. If this causes you skin damage in any way, then you need to consult with doctor Akoury and seek for an appointment with her for more professional assistance today.

Effects of breast cancer on your beauty: Why Radiation are the major problem?

Estrogen Dominance and Hormonal Imbalances

February 6, 2015

Estrogen Dominance and Hormonal Imbalances

Estrogen dominance describes a state in which a woman can have insufficient, normal or too much estrogen, but has little or no progesterone to match or balance its effects in the body.

Hormones are very important in the normal body functioning. When the hormones are not working as they should then a hormonal imbalance occurs. Hormonal imbalance is very common especially among women and it’s the leading causes of weight loss difficulties. Hormonal imbalance also increases obesity risks in females especially.

Women more than men, are likely to experience an imbalance in their hormones. In women menopause is the leading causes of hormonal imbalances. However, contrary to popular belief, there are other factors that may throw your hormones off balance. Such include things like medication, lifestyle as well as pregnancy. Stress also among the causes of hormonal imbalances in both men and women.

Underneath this hormonal imbalances are healthy problems that occur as a result. Such imbalances lead to things like moods swings, hot flashes, depression, weight gain, heavy breeding, migraines, and fibroids among others. Weight loss is very difficult when your hormones are not balanced for example, estrogen.

estrogen-dominance

Estrogen Balance

It is an important factor while trying to maintain weight as well also in losing some. It is often associated with belly fat when its levels are not balanced. Estrogen imbalance is common in men and women who are experiencing premenopause. It leads to bloating, water retention, fat gain and other health issues. In women, age and stress lead to the progesterone and testosterone levels decline and this leaves the body with too much estrogen.

Women and men who have an excess of estrogen hormone end up gaining weight with the concentration being around the abdomen and hip. This is generally what leads to belly fat. When the levels of estrogen are not restored back to normal, weight loss is very difficult no matter how much effort you put into it.

You have probably come across people who no matter how much of good diet and exercise they take they just can’t seem to shed off those extra pounds. This can be a real issue and it ends up affecting the quality of your life. Just like poor diet and lack of enough exercises, high levels of estrogen in the body are a risk factor of obesity. It is common knowledge that obesity leads to health conditions such as heart attack and high blood pressure.

Estrogen Dominance

Estrogen dominance is a sad state for a woman to find herself medically speaking. When estrogen is in excess in the body it will in most cases lead to considerable weight gain. So what brings about excess estrogen in the body? Most often excess estrogen will often arise when the body produces too much of it, when levels of other hormones such as progesterone and testosterone reduce and also through our diets and lifestyles.

Most of the foods we eat contain compounds such as herbicides and pesticides which are toxic and contain growth hormones. Such compounds take the nature of estrogen and when ingested into the body, the result is an increased level of the hormone creating an offset in the balance that normally exists. Most of these toxics have been shown to lead weight gain and promote estrogen dominance to a certain degree.

Age and stress are also factors that lead to an increase in the levels of hormone estrogen. What happens is that as we age especially women the level of other hormones like progesterone decreases but the levels of estrogen do not decline. This leads to an increased level of the estrogen dominance which leads to an imbalance that translates into health issues like obesity. As you gain weight, insulin resistance occurs whereby the body resists the insulin that is produced by the body. Thereby, with insulin resistance, the risk of estrogen dominance increases.

hormonal-imbalance

How to Correct Hormonal Imbalance

As seen, hormonal imbalance is often caused by medications, toxics, poor eating habits and lifestyle choices. So how do we correct this hormonal imbalance?

Avoid Toxics: compounds such as pesticides and herbicides contain toxics and growth hormones. These mess up the hormonal balance that usually exists leading to an increase in the levels of estrogen hormone in the body. To avoid this, always wash vegetables and fruits well before consumption.

Change your lifestyle: almost every medical expert will tell you that the lifestyle you lead may either improve or destroy your health. Change your eating habits by starting to take a well-balanced diet. Also find time to regularly exercise because, weigh gain is a risk factor for estrogen dominance.

Supplements: there are hormone supplements that contain hormones that are meant to restore the balance again. Visit your doctor for more information on the kind of hormones you should take.

Avoid stress: sometimes you may find yourself going through a stressful situation. Always try to avoid such situations by focusing on the positive side of life. Stress is a factor that can wreak havoc to your hormones throwing them completely out of balance.

Dr. Akoury has years and years of experience in the medical arena. Many patients bear witness to her good work in wellness and awareness tips she offers them. Become a part of this successful journey and join the community at www.awaremednetwork.com today. Both Estrogen dominance and hormonal imbalance are well taken care of at Awaremed Health and Wellness Centre.

Estrogen Dominance and Hormonal Imbalances

The Relationship between Obesity and Cancer

February 2, 2015

The Relationship between Obesity and Cancer: Different types of Cancers Discussed

The Relationship between Obesity and Cancer can not be taken for granted. Both are chronic in nature and can do great harm if not addressed timely

Even though overweight or obesity doesn’t cause cancer, it is one of the major risks factors of various types of cancers. We talked with experts at AWAREmed Health and Wellness Resource Center to help us understand the relationship between obesity and cancer and that is what we want to discuss in this article. we may not exhaust all the types of cancers but we are going to share with you as much as we can and request you to schedule for an appointment with doctor Dalal Akoury who is also the founder of this facility and she will be able to take you through all your concerns. The following are some of the types of cancers we want to look at:

Breast cancer
Endometrial cancer
Colorectal cancer
Kidney cancer
Esophageal cancer
Pancreatic cancer
Thyroid cancer
Gallbladder cancer

The Relationship between Obesity and Cancer: Breast cancer

In the recent past several research findings have established that overweight and obesity are closely associated with a modest increase in risk of postmenopausal breast cancer. This higher risk is projected mainly in women who are yet to use menopausal hormone therapy (MHT) and for tumors that express both estrogen and progesterone receptors. And on the other hand overweight and obesity have, by contrast, been found to be associated with a reduced risk of premenopausal breast cancer in some research findings.

Ideally the connection between obesity and breast cancer is likely to be affected by the stage of life in which a woman gains weight and becomes obese. Efforts are being made by the epidemiologists to address this question. The victim age bracket that is mostly affected includes adults of between 18 and 60 years. The increased risk of postmenopausal breast cancer is however thought to be due to increased levels of estrogen in obese women. After menopause, when the ovaries stop producing hormones, fat tissue becomes the most important source of estrogen. Because obese women have more fat tissue, their estrogen levels are higher, potentially leading to more rapid growth of estrogen-responsive breast tumors.

The Relationship between Obesity and Cancer: Endometrial cancer

Overweight and obesity have been constantly associated with endometrial cancer. This is that type of cancer that affects the lining of the uterus. Indications are that obese and overweight women have two to four times the risk of developing this disease than women of a normal weight, regardless of menopausal status. The experts have also established that the risk of endometrial cancer goes up with weight gain increase in adulthood and more so in women who have never used MHT.

The Relationship between Obesity and Cancer: Colorectal cancer

This is particularly significant in the male gender. It has been found that being obese increases the risk of colorectal cancer. The distribution of body fat appears to be an important factor, with abdominal obesity, which can be measured by waist circumference, showing the strongest association with colon cancer risk.

An association between BMI and waist circumference with colon cancer risk is also seen in women however in relation to men, the relationship is a bit weaker. Nevertheless the use of MHT may modify the association in postmenopausal women. High BMI is also associated with rectal cancer risk, but the increase in risk is more modest.

The Relationship between Obesity and Cancer: Kidney cancer

Periodically obesity has been in many ways associated with renal cell cancer, which is the most common form of kidney cancer, in both men and women. The mechanisms by which obesity may increase renal cell cancer risk are not well understood. High blood pressure is a known risk factor for renal cell cancer, but the relationship between obesity and kidney cancer is independent of blood pressure status. However the high levels of insulin may play a role in the development of the disease.

The Relationship between Obesity and Cancer: Esophageal cancer

Overweight and obese people are about twice as likely as people of healthy weight to develop a type of esophageal cancer called esophageal adenocarcinoma. Most research findings have observed no increased risk, or even a decline in risk, with obesity for the other major type of esophageal cancer, squamous cell cancer. It must be made clear that at the moment the mechanisms by which obesity may increase risk of esophageal adenocarcinoma are not well understood. However, overweight and obese people are more likely than people of normal weight to have a history of gastroesophageal reflux disease or Barrett esophagus, which are associated with an increased risk of esophageal adenocarcinoma. It is possible that obesity exacerbates the esophageal inflammation that is associated with these conditions.

Pancreatic cancer – Many studies have reported a slight increase in risk of pancreatic cancer among overweight and obese individuals. Waist circumference may be a particularly important factor in the association of overweight and obesity with pancreatic cancer.

Thyroid cancer – Increasing weight has been found to be associated with an increase in the risk of thyroid cancer. It is unclear what the mechanism might be.

Gallbladder cancer – The risk of gallbladder cancer increases with increasing BMI. The increase in risk may be due to the higher frequency of gallstones, a strong risk factor for gallbladder cancer, in obese individuals.

The Relationship between Obesity and Cancer: Does avoiding weight gain or losing weight decrease the risk of cancer?

The most conclusive way to test whether avoiding weight gain or losing weight will decrease the risk of cancer is through a controlled clinical trial. A number of NIH-funded weight loss trials have demonstrated that people can lose weight and that losing weight reduces their risk of developing chronic diseases, such as diabetes, while improving their risk factors for cardiovascular disease.

However, previous trials and the results of an NCI workshop have demonstrated that it would not be feasible to conduct a weight loss trial of cancer prevention. The reason is that the effect of weight loss on the prevention of other chronic diseases would be demonstrated and the trial consequently stopped so that the public could be informed of the benefits before the effect on the prevention of cancer would become evident. Nevertheless, many observational studies have shown that people who have a lower weight gain during adulthood have a lower risk of:

Colon cancer
Breast cancer (after menopause)
Endometrial cancer

Finally dear reader, from the discussion it is obvious that there are some great truth about the relationship between obesity and cancer. If you understand the tow conditions, then you will want to distances your life with these chronic conditions. We have a duty as experts at AWAREmed Health and Wellness Resource Center to help you get out of this problem in the most professional way. This facility is under the able leadership of doctor Dalal Akoury’s care and talking to her will be the starting point towards your total recovery from all these unpleasant chronic conditions. You can schedule for that very important appointment with her today for the commencement of your journey to total recovery.

The Relationship between Obesity and Cancer: Different types of Cancers Discussed

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