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Methylation and Addiction

February 6, 2015

The Mechanisms in Methylation and Addiction

Addiction refers to a very strong need to take something like drugs or do particular activities. Addictions are so strong that people think they have no control over them. Addiction becomes one of the important things in your life. Due to this it ends up affecting the quality of your life as well as your relationship with others.

Addiction occurs when one feels they should take something like drugs or alcohol or carry out a particular activity such as gambling. Today addiction affects people across all ages. There is no known reason why people get addicted to something. However, regular intake of drugs or gambling may result in the person’s life getting tuned to that particular choice. People get strongly attached to these things and they feel the need to repeat the same thing over and over again. This way they become addicted to that thing and it becomes an important part of their life.

What is methylation?

Methylation basically refers to the process of adding a methyl group to a substance or simply replacement of an atomic group with that of a group of methyl. It is takes place where a methyl group undergoes alkylation instead of the normal hydrogen atom replacing a carbon chain. Such terms apply in biochemistry, chemistry, biological sciences as well as soil science.

Methylation and Addiction

In biological sciences for instance methylation involves the enzyme catalyzation. This form of methylation is responsible for heavy metal modification, gene expression regulation, processing of RNA as well as regulation the functioning of proteins in the body. Heavy metal methylation often takes place outside the biological system. Reduction of histological staining is made possible by the chemical methylation of tissues in the body.

Methylation in the body

It is one of the important processes that take place in the body.  It takes place when the body receives a substance and converts it to another. This is basically so that the substance can be removed from the body. Methylation takes place in the liver during the second detoxification phase a billon times per second.

In order to understand detoxification, there is need to look at what makes up a methyl group. A methyl group is basically made up of three atoms of hydrogen. Methylation takes place when S-adenosine methionine (SAMe) gives out a methyl group that is then attached to the molecule that undergoes detoxification.  The SAMe s then converted to homocysteine. The methylation process must occur often in order to detoxify the body regularly. Buildup of toxics in the body leads to poisoning of cells which can lead to serious medical conditions a like inflammation and cancer. The methylation process is kept going by vitamin B12, B6 as well as folic acid. These substances are necessary in the body in order to facilitate homocysteine reduction to facilitate the process of methylation.

Homocysteine is an amino acid that is naturally toxic to the body. If left to accumulate it can prove toxic to the cells leading to several health conditions. If methylation does not take place as it should a person can suffer from conditions like stroke, cancers of the reproductive system, colon cancer, Alzheimer’s disease, heart disease, defects of the neural tubes, impairment in DNA repair, kidney infarct, impaired detoxification and dysplasia among others.

Faulty methylation leads to the levels of homocysteine increasing. This leads to poisoning of the cells and tissues. However, studies show that B vitamins facilitate lowering of the levels of homocysteine in the body and therefore reducing the risk of a person getting disease like stroke and heart attack.  Common belief among people is that the main cause of heart attack is in accumulation of cholesterol in the body therefore they cut out their intake of cholesterol in their foods. However, studies show that only a fraction of people who suffer from heart attacks is as a result of cholesterol build up in the body. This being the case, other people who suffer from heart disease may be because of buildup of homocysteine in the body.

Methylation and Addiction

Methylation and Addiction

Recent research studies show that over exposure to certain drugs facilitates chances in methylation levels in the bloods. The same also promotes DNA methylation levels to be altered. DNA methylation takes place in the brain neurons. The altered level of methylation promotes altered levels in gene expression this can happens when one is addicted to certain substances like drugs and alcohol.

Basically methylation is used in DNA. Naturally, each cell in the body contains DNA of other cells. Methyl groups that occur naturally in the body are responsible from suppression of DNA that should not be read. When there is poor methylation due to an addiction to drugs or alcohol, the methyl groups are removed from the genes in order to be used in other body processes. This removal of a methyl group is what leads to cancer expression in the body.

For more information about methylation and addiction, visit www.awaremednetwork.com today. Here you will also find other helpful health and awareness tips. Dr. Dalal Akoury will provide assistance with any information you may need.

The Mechanisms in Methylation and Addiction

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DCA Cancer Treatment

December 10, 2014

DCA Cancer Treatment

There are over 14.1 million cases of cancer in the world today. Each day new cases of cancer are reported. One in very three people is bound to develop some kind of cancer.

There are over 100 types of cancer in the world. The most common being breast cancer, prostate cancer, bowel cancer, lung cancer and colon cancer. Cancer treatment has been advanced through technology. Cancer affects different people from children to the old folks and for this reason; studies are coming up with different methods of treating the disease.

dca-and-cancer-treatment

The most common forms of cancer treatment include surgery, chemotherapy, radiation therapy, immunotherapeutic approach among others. The kind of cancer treatment depends on how advanced it is. Cancer stages range from stage I which is the mild stage of cancer to stage IV which is the most extreme.

Patients with cancer undergo a lot of pain that can only be managed though certain medications. When cells begin to grow uncontrollably, they emit toxics in to the tissues that cause the pain. A patient is put through therapy where the doctors try to destroy the cancer cells in the body. Some therapy eliminates all traces of the cancer but in some cases the cancerous cells return after a period of time.

Cancer begins from a tumor that forms from the over growing of cells around a tissue. Not all tumors are malignant. The one that turn out to be can end up spreading to other parts of the body infecting them as well. This spreading of the cancerous tumors to other parts of the body is referred to as mitosis. Most forms of cancers are caused by infections and very result from viruses.

 What Is Dichloroacetate?

It is man-made chemical that is not found in nature. It is used in the making of certain chemicals as well as drugs. The chemical can be absorbed through the skin. In its pure form, it acidic and can cause burns and tissue injuries.

Due to its applicability in making drugs the chemical has been found to eliminate different kinds of cancers. Breast cancer, lung cancer, prostate cancer, colon cancer as well as lymphoma have all shown amazing results with the use of dichloroacetate in treatment.

It is prescribed in USA, Canada and most parts of Europe. It is however not sold legally as a medication unless under a doctor’s advice.

How DCA works in cancer treatment

Cancer attacks the cell causing them to grow at a faster rate than is normal. This uncontrollable growth of cells causes formation of tissue masses called tumors. Tumors refer to that thin layer of uncontrollably growing cells surrounding a dead tissue.

As cells in the tumor continue to grow they release toxics into the host tissue. These toxics have been linked to severe pains in cancer patients. Normally cells respire aerobically in the presence of oxygen to release energy by breaking down glucose. Cancerous cells survive in low oxygen. In this case they cause glucose to be fermented. This fermentation causes the formation of an acidic environment which leads to a drop in pH in the body.

Research done in the lab showed that prostate cancer cells exposed to DCA seemed easier to destroy with radiation after this.  Breast cancer inserted in the tails of rats seemed to spread to fewer places after being exposed to DCA.  Cancer cells from the womb lining on the other hand, seemed to die with exposure to DCA.

DCA-Cancer-Treatment

DCA works by causing the cancerous cells to die naturally a process called apoptosis. It does not poison the cells. Instead it works by altering the ability of the cancer cell to use glucose. Because cancer cells depend on glucose to produce energy with little oxygen, the cells are deprived of energy. Once this happens, they naturally die. While this happens healthy cells are not deprived of the much needed glucose. They continue producing energy that enables them to carry out different body functions.

These research studies carried out basically show the effectiveness of DCA in killing different types of cancer cells like prostate, breast and colon cells. They also show that DCA is very effective in boosting killing effects of cancer such as chemo, radiation and cancer drugs.

DCA has also been studied and shown to cure other illnesses other than cancer. Lactic acid is not a life threatening condition. However accumulation of lactic acid for a long time may prove fatal for people. DCA has been shown to work effectively in trying to reduce lactic acid in the body.

Dr. Dalal Akouri had for years acquired experience in dealing with terminally ill patients. She has immensely improved the lives of these patients. Her experience in life threatening illnesses has made many patients improve and lead a healthy life. Just visit www.awaremednetwork.com for more information about her and more healthy tips.

DCA Cancer Treatment

 

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Genetic Predisposition

August 5, 2014

 

Genetic and Viral Predisposition To Cancer Is A Crucial Subject In Cancer Treatment

Cancer has caused serious threat to the world’s population and has still continued to affect the people of all continents. It is among the leading causes of death in the world today. Despite the many alternative cancer treatments, the disease is not yet conquered as it is still causing pain to us every day after grabbing our loved ones away from us. According to a world health report of 2002, close 7.1 million deaths are caused by cancer each and every year. With the most prevalent of these cancers being lung, stomach, colon, liver, breast and esophagus cancer, in that order of occurrence. Conclusively, these cancers are responsible for over 4.2 million deaths. Additionally, another World Cancer Report of 2003 (IARC 2003) predicts that deaths caused by cancer will increase by 50% in the next 20 years. In the past cancer was thought of as diseases of the developed countries but as years passed by even the third world countries became infested with this disease. The cases of cancer in the third world countries are attributed to the demographic changes as well as changes in lifestyle. The way of life has changed even in these third world countries and this may even increase the percentages of cancer infection.

Cancer is a disease that has many causes and of the many cause are very complex gene interactions. A person may not be born with cancer but he may have higher chances of getting cancer. This is what is known as genetic predisposition. Genetic predisposition maybe caused by a presence of one or more gene mutations and this may happen even if the allele’s combination is normal.

Genetic predispositisions is a subject that has made researchers as well as health organizations like World Health Organization to do lot of research work to find out how far genetic predisposition can lead to the disease. Apparently the researches done were not only done in relation to cancer but other non-communicable diseases like diabetes, cardiovascular disease, asthma, and some mental illnesses.

In cancer, a person may be born with genes whose compositions were altered by lifestyle habits or exposure to harmful chemicals that goes along way in changing the DNA composition of the body cells. The body has tumor suppressors that help it in fighting and preventing tumors but when these tumor suppressors become weak which may be caused by exposure to harmful chemicals then a person becomes more vulnerable to cancer infection. Carcinomas are the most probable result of failure of the tumor suppressors.

It is important to understand how genetic predisposition affects a person. Cancer is not a disease that should be toyed with and so it calls for early examination to show whether a person has genetic predispositions that can play a role in making them to have cancer. Doctors advice that by knowing if a person has these genetic predispositions, it can help them to adopt lifestyles that will help them evade the formation of cancer cells in them. It is good to note that not all people who are born with genetic predispositions to cancer eventually get the disease; the choice of lifestyle will either make him evade the disease or will even hasten the formation of the cancerous cells in them. Those who are born with genetic predispositions to cancer can avoid the disease by avoiding such behaviors that may increase their risk to cancer such as smoking tobacco, drinking alcohol and engaging in sexual activities with many sexual partners. There are lifestyle modifications that will help a person who is born with genetic predispositions to cancer live longer without being affected by the disease. These may involve healthy eating and detoxifying the body naturally by eating those vegetables and fruits that are rich in antioxidants. It is also advisable for such a person to seek help from an integrative cancer centre where the doctors may offer guidance on how to live a life that is cancer free despite the genetic predisposition to cancer he was born with.

Promotes cancer cell formation

As known, cancer cell forms when there is mutation in the genes that play a major role in cell multiplication and repair. When these mutated genes are passed over to an offspring, the offspring becomes highly vulnerable to cancer. However the process through which these genes may turn cancerous may take time probably beyond 20 years. The mutation of vital genes such as suppressor genes, oncogenesis and genes involved in DNA repair leads to genetic instability and to progressive loss of differentiation. Tumors grow because cancer cells lack the ability to balance cell division by cell death and by angiogenesis. The transformed cells lose their ability to interact with each other and exhibit uncontrolled cell growth. They will eventually invade the tissues that surround them and spread into the blood stream after which they can reach very organ in the body.

GeneticGenetic predisposition to cancer undeniably has a role in cancer formation. One of the mostly inherited mutations of BRCA 1 gene is known to cause breast cancer in women. Those who have this gene mutation have higher chances of getting a breast cancer as well as ovarian cancer. Earlier identification of the germline mutations can be achieved through genetic testing. This will allow the person to adopt cancer preventive measures by seeking help from integrative cancer centers that will give natural means of suppressing the mutated gene expression.

Dr. Dalal Akoury is an experienced integrative cancer doctor who has seen very many cancer patients journey to victory in their fight against cancer. She is available for consultations. Just call her now and begin your journey to victory against cancer.

Genetic and Viral Predisposition To Cancer Is A Crucial Subject In Cancer Treatment

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