Tag Archives: Attention Deficit Hyperactivity Disorder

Treatment for Attention Deficit Hyperactivity Disorder

Treatment for Attention Deficit Hyperactivity Disorder: The two Components of ADHD

Treatment for Attention Deficit Hyperactivity Disorder

Treatment for Attention Deficit Hyperactivity Disorder Symptoms include difficulty staying focused and paying attention, difficulty controlling behavior, and hyperactivity (over-activity

The joy of being healthy cannot be compared with anything and cannot be quantify into monetary value. The problem we have today is that such important assets are seriously under immense threat and is being attacked by diseases from all directions and in all ages. Some of the diseases can begin even before conception and by the time one is born, the magnitude of the problem is unbearable. This link is objectively design to bring to your attention the health information from various health conditions and today we want to look at the available treatment for attention deficit hyperactivity disorder (ADHD). Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood disorders and can continue through adolescence and even into adulthood. Symptoms include difficulty staying focused and paying attention, difficulty controlling behavior, and hyperactivity (over-activity). This condition has two important components to look at it from; the psychological interventions and medications. Doctor Akoury says that there are adequate evidences from various studies that medication alone may not effectively help the primary issues affecting the patients whether they are children or adult. Therefore it is very important that the patients’ needs to know more about this condition inside out to be able to successful while living with the disorder. That now introduces into understanding the symptoms of ADHD.

Treatment for Attention Deficit Hyperactivity Disorder: Signs and Symptoms

Inattention, hyperactivity, and impulsivity are the key behaviors of ADHD. It is normal for all children to be inattentive, hyperactive, or impulsive sometimes, but for children with ADHD, these behaviors are more severe and occur more often. To be diagnosed with the disorder, a child must have symptoms for 6 or more months and to a degree that is greater than other children of the same age. Children who have symptoms of inattention may demonstrate the following:

  • They can easily be distracted, miss details, forget things, and frequently switch from one activity to another
  • Have difficulty focusing or concentrating on one assignment
  • Become bored with a task after only a few minutes, unless they are doing something enjoyable
  • Have difficulty focusing attention on organizing and completing a task or learning something new
  • Have trouble completing or turning in homework assignments, often losing things (e.g., pencils, toys, assignments) needed to complete tasks or activities
  • Not seem to listen when spoken to
  • Daydream, become easily confused, and move slowly
  • Have difficulty processing information as quickly and accurately as others
  • Struggle in following given instructions.

Children who have symptoms of hyperactivity may demonstrate the following:

  • Fidget and squirm in their seats
  • Be talkative
  • Dash around, touching or playing with anything and everything on sight
  • Have trouble sitting still during dinner, school, and story time
  • Be constantly in motion
  • Have difficulty doing quiet tasks or activities.

Children who have symptoms of impulsivity may demonstrate the following:

  • Be very impatient
  • Blurt out inappropriate comments, show their emotions without restraint, and act without regard for consequences
  • Have difficulty waiting for things they want or waiting their turns in games
  • Often interrupt conversations or others’ activities.

Treatment for Attention Deficit Hyperactivity Disorder: Treatments

Because of the nature of this condition treatment is very important to be administered in good time after evaluating the symptoms for the six months. Interestingly at the moment doctor Akoury says that the available treatments is majorly focusing on the reduction of the symptoms of ADHD and improving functioning. When you pay a visit to any health facility where ADHD treatment is offered like at AWAREmed Health and Wellness Resource Center a facility established by doctor Dalal Akoury, when the relevant test have been done, treatments will include medication, various types of psychotherapy, education or training, or a combination of treatments. It is however very important to note that, these treatments will relieve many disorders symptoms even though there is no cure. When treatment is done effectively, many patients are able to get better and be successful in there academics for a better life in the future. A lot of studies are currently being done to establish the actual treatment and interventions of ADHD.

Treatment for Attention Deficit Hyperactivity Disorder: Medications

Stimulant is the most common type of medication used for treating ADHD. Although it may seem unusual to treat ADHD with a medication considered a stimulant, it actually has a calming effect on children with ADHD. Many types of stimulant medications are available. A few other ADHD medications are non-stimulants and work differently than stimulants. For many children, ADHD medications reduce hyperactivity and impulsivity and improve their ability to focus, work, and learn. Medication also may improve physical coordination. And even though medication will work better in offering solutions to ADHD patients and more so in children, it is important to note that the same medication may not work in the same manner with every child patient. In other words what works for one patient may not really work for the other. One child might react with the medication negatively and yet another may not. For effectiveness it may necessitate that different medications or dosages must be tried before finding one that works for a particular child. Therefore any child taking medications must be kept under close observation by their health professionals during this period.

Finally stimulant medications come in different forms including the pills, capsule, liquid or skin patch. Some medications also come in short-acting, long-acting, or extended release varieties. In each of these varieties, the active ingredient is the same, but it is released differently in the body. Long-acting or extended release forms often allow a child to take the medication just once a day before school, so they don’t have to make a daily trip to the school nurse for another dose. Parents and doctors should decide together which medication is best for the child and whether the child needs medication only for school hours or for evenings and weekends too. ADHD can be diagnosed and medications prescribed by medical doctors who are usually practicing psychiatrist though in some states the prescription could also be done by clinical psychologists, psychiatric nurse practitioners, and advanced psychiatric nurse specialists.

Treatment for Attention Deficit Hyperactivity Disorder: The two Components of ADHD

 

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Herbs For Pain and Addiction Treatment

Use of Jamaican Dogwood, Valerian, Wood Betony, Yellow Jasmine in Pain and Addiction Treatment

Addiction is still one of the major problems that we are still living with today. Though known for its devastating effects, addiction has still remained when of the many menaces that our youths as well as the older generation alike are still glued to. However there is a bitter reality that you need to be aware of, a reality that none of your already addicted friends will let you know of; the journey to addiction treatment and recovery is that which is not easily won. There are serious hurdles that you shall have to meet along the way as you fight on to reach the greener side of life where the chains of addiction are broken. Just like any other disease there are myriads of ways through which the treatment of addiction can be effected. one is through pharmaceutical ways of treatment and the other through natural ways of treatment that may at times be used alongside the orthodox ways of treatment or as an assortment of various herbs and a special choice of diets that helps restore the damage of drugs on the addict and hence making it possible for the addict to be treated of the illness. On the other hand when pharmaceuticals are used for treating drug addiction the doctors will mostly use a substitute of your drug to satisfy your craving for the drug of abuse you are addicted to. Though this may present a short term solution it still doesn’t let you be free from the drug as you will still continue using a substance that is thought to be less addictive and not so dangerous. However the reality is that this kind of treatment does not address the brain imbalances that an addict suffers after a long term use of a certain drug.

Addiction Treatment

As we have seen in previous articles the part of the body that is adversely affected by addiction to drug abuse is the nervous system. The neurotransmitters like the dopamine and the other crucial ones are literally damaged after a prolonged use of drugs. this therefore calls for a treatment option that will not only focus on ending the craving that addicts have for their substance of abuse but to help restore the whole person back to what he or she was before he got into drug use that has since chained him or her. Most pharmaceutical drugs do not consider this but mostly gear towards treating the symptoms of addiction like depression and anxiety that is normally done with sedatives while the underlying problem; the damage to the nervous system, is left unchanged. Through the years there have been different alternatives to addiction that have since come up and have been found to be effective. An example of these alternative therapies that have shown hope to addicts is the use of stem cell therapy that aims at restoring the damage caused by drugs. Despite the effectiveness of some of these alternatives the use of herbs in addiction treatment is yet to be scrapped off, this is solely because of the effectiveness of some herbs in treating addiction. Here are some of the herbs that can be used to help in the addiction treatment and recovery.

Jamaican Dogwood

Jamaican dogwood is mostly used for pain. It has sedative effect, reduces muscle spasm and cools nerve pain. It also reduces inflammations. It has often been the top choice for relieving nerve pain and it has been proved to be powerful in pain management.  It is derived from the bark of the dogwood tree, and can be taken in capsule or tincture forms as well as a tea from the bark’s powder.  Though known for pain management it can contribute in help with addiction as when used it helps to calm down the nerves and relive an addict off the withdrawal effects like depression and anxiety that most of the times can lead to relapse. However beneficial it is it can be potentially dangerous when used for self-medication. It is therefore safe to use it with instructions from an integrative addiction doctor as it is irritant and can cause numbness, tremors, salivation, and sweating.

Wood Betony

Wood Betony

This herb is commonly found in Europe. This plant is rich in medicinal properties. To begin with the fresh, undried leaf of wood betony is a natural pain reliever. This analgesic is good for addiction as it helps in calming the nerves as well as fighting some common symptoms of addiction like depression anxiety and insomnia.

Valeria

Valeria has great sedation properties. As have been revealed by past literature, Valeria has great influence on the cerebro-spinal system. In a recovering addict this herb can be used to promote nerve relaxation and sleep. Insomnia is a common symptom that most addicts battle with, with valerian a recovering addict can be helped evade the grave effects of insomnia and anxiety. It does this by exerting an influence quieting and soothing in its nature upon the brain and nervous system. Other herbs that have been found to be helpful in the journey of addiction treatment and recovery are; Yellow Jasmine, St. Johns worts and chamomile among others

Finally, Here at AWAREmed Health and Wellness Resource Center we are committed to availing help to addicts by availing some of the most integrative approaches to healing an addict. We advocate for natural healing to all kinds of addiction. Call on Dr. Dalal Akoury (MD) at Myrtle Beach, South Carolina for help.

Use of Jamaican Dogwood, Valerian, Wood Betony, Yellow Jasmine in Pain and Addiction Treatment

 

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Striatum Methamphetamine Toxicity

Methamphetamine Toxicity in the Striatum

The striatum is a crucial part of the brain. This part of the brain plays very important roles but it can be adversely affected by the use of stimulants and other drugs of leisure. Substances such as cocaine and methamphetamine produce their primary effects inside the brain by boosting the presence of dopamine which is a neurotransmitting chemical that activates the pleasure-producing neurons contained within the limbic system. As stated above the limbic system includes the hippocampus, along with several other brain structures. According to the results of two separate studies published in 2008 in the Journal of Neuroscience and Biological Psychiatry, the presence of either cocaine or methamphetamine alters normal adult neurogenesis inside the hippocampus and damages this region’s ability replenish its neuron supply.  It is no longer news that methamphetamine intoxication causes long-lasting damage to dopamine nerve endings in the striatum. However the mechanisms underlying this neurotoxicity are not yet known but oxidative stress has been linked to it.

methamphetamine

 

Microglia are the major antigen-presenting cells in brain and when activated, they secrete an array of factors that cause neuronal damage. Astoundingly, very little work has been directed at the study of microglial activation as part of the methamphetamine neurotoxic cascade. It has been report that methamphetamine activates microglia in a dose-related manner and along a time course that is coincident with dopamine nerve ending damage. Through tests done on mice scientists have discovered that prevention of methamphetamine toxicity by maintaining treated mice at low ambient temperature prevents drug-induced microglial activation. MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) not only damages dopamine nerve endings and cell bodies but also  causes extensive microglial activation in striatum as well as in the substantia nigra. Contrastingly, methamphetamine causes neither microglial activation in the substantia nigra nor dopamine cell body damage.

Dopamine transporter antagonists do not mimic the effect of methamphetamine on microglia. Hyperthermia, a prominent and dangerous clinical response to methamphetamine intoxication, has been also ruled out as the cause of microglial activation. Together, these data suggest that microglial activation represents an early step in methamphetamine-induced neurotoxicity. Other neurochemical effects resulting from methamphetamine-induced overflow of dopamine into the synapse, but which are not neurotoxic, do not play a role in this response.

Methamphetamine use on the rise despite effects

The use of methamphetamine has been on the rise despite the fact that it is a powerful stimulant drug that has adverse effects when abused as most people do. According to the UN Office on Drugs and Crime reported recently that abuse of amphetamines, including designer drugs such as methamphetamine and 3, 4-methylenedioxymethamphetamine, now exceeds that of cocaine and heroin on a global scale. This presents no sign that its use will decline any soon. Past researchers were able to establish a fact that methamphetamine causes persistent reductions of function in dopamine nerve endings of animals and humans. Methamphetamine neurotoxicity has been under intense study for over 20 years, but still there is much that still remains to be learned about how this dangerous drug causes damage to dopamine nerve endings. The theory that revolves around oxidative stress has been at the top of the speculations. Drug-induced oxidative stress is an attractive construct that can account for many of the effects of methamphetamine on the dopamine nerve ending such as inhibition of tyrosine hydroxylase activity as well as reductions in the dopamine transporter and the vesicle monoamine transporter. This may even be an early event that leads eventually to methamphetamine-induced apoptosis. However, the source of the reactant species that mediate methamphetamine-induced damage is not known.

methamphetamine

Due to their crucial roles they play in mediating the mediating damage to the nervous system, Microglia has attracted considerable attention. Immune like in many ways  these interesting cells become activated by damage and then transmigrate to sites of injury where they can secrete an array of factors  like cytokines, prostaglandins, nitric oxide, and superoxide that are known to have detrimental effects on neurons. However, the role of microglia in methamphetamine-induced damage to the dopamine system has received little attention. In 1994 a researcher, Bowyer and his colleagues noted for the first time that methamphetamine resulted in activation of microglia in striatum of treated rats. These investigators concluded that microglia were increased in response to nerve ending damage and were not apparently a cause of it.  Recently, another research was conducted to give an in-depth analysis of the effect of methamphetamine on striatal gene expression. Numerous genes linked to microglia were activated significantly within hours of methamphetamine intoxication, suggesting the possibility that microglial activation occurs earlier in the methamphetamine toxic cascade than previously thought.

Today there are researchers who are building on the initial analysis of methamphetamine and report the pharmacological characterization of microglial activation by methamphetamine in striatum. As mentioned before, striatum is an area dense in dopamine nerve endings and is known to be targeted for damage by methamphetamine. Microglial activation coincides with the onset of methamphetamine-induced damage in striatum and the extent of this effect is related to the degree of damage to dopamine nerve endings. Numerous nontoxic effects exerted by methamphetamine, such as inhibition of the DAT, increases in synaptic levels of dopamine, activation of D1 and/or D2 DA receptors, and hyperthermia, cannot explain methamphetamine-induced microglial activation.

Finally, this is still a dark area and there is need for more literature so as to establish the mechanism of methamphetamine toxicity on the striatum. Needless to say, Drug abuse, addiction and independence are problems that people grapple with every day. These problems need to be treated effectively through integrative medicine. Dr. Dalal Akoury (MD) is an expert at this.  Call her on (843) 213-1480 for help.

Methamphetamine Toxicity in the Striatum

 

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Molecular Mechanisms of Methamphetamine Induced-Neurotoxicity

Methamphetamine is a stimulant that is also highly soluble in water and affects the CNS most. Categorically it fits in the group of synthetic drugs chemically related to amphetamine but it has more adverse effects on the Central nervous system than the parent compound. Abuse of these illegal psychostimulants has become an international public health problem, with an estimated 14 to 52 million amphetamine-type stimulant users worldwide, exceeding the total number of cocaine abusers and second only to the number of cannabis abusers. This number has continued to rise in spite of the fact that much has been done to publicize the adverse effects these amphetamine related stimulants are linked to. Meth or speed as known in stimulant use circles exists in different forms like powder, tablets and capsules. It can also be found in a purer crystalline form.

It’s dangerous why is it used?

Just like most stimulants or drugs that are known to induce euphoric feelings, methamphetamine is also taken for similar reasons for example; to induce euphoric feelings, increased sense of well-being, increase energy and to calm anxiety. Being a powerful drug its effects are felt immediately after the use but these effects can last for long hours. They may be accompanied by acute adverse effects such as increased blood pressure and heart rate, which may cause irreversible damage to blood vessels in the brain, resulting in cerebrovascular accidents, stroke, and death. Methamphetamine also produces hyperthermia, pupil dilation, flushing, tremors, trismus and bruxism, muscle tension, loss of appetite or anorexia, and loss of pleasure in food intake which further leads to deterioration of the user’s health.

methamphetamine

Effects of Methamphetamine

Being an addictive drug, after a prolonged use the users may develop tolerance. It’s most common symptoms after a prolonged use include; temporomandibular joint syndrome, dental erosion, and myofacial pain. Long-term use also produces lack of appetite, weight loss, accelerated aging, nose-bleeding problems, nonhealing wounds, tooth decay and fracture known as “Meth mouth”. Psychiatric symptoms include anxiety, depression, increased aggression, social isolation, psychosis, mood disturbances, and psychomotor dysfunction. Long periods of high consumption can cause paranoid psychosis. Other symptoms of chronic methamphetamine use may also include; deficits in attention, working memory, and decision making. Most addicts are stuck in the use of meth as a result of the withdrawal symptoms which include the following; irritability, fatigue, impaired social functioning, and intense craving for the drug. Researchers have given evidence that the negative neuropsychiatric consequences of methamphetamine abuse are due, at least in part, to drug-induced neuropathological changes in the brain. Although the exact molecular mechanisms of neuronal body loss are not known, there is evidence to suggest the coexistence of different types of cell death, including apoptosis and necrosis ; indicated by the morphology of neurons stained with hematoxylin-eosin.  Growing evidence exhibits that methamphetamine and MDMA induce an increase in lipid peroxidation and DNA oxidation as well as increased levels of oxidative stress markers such as hydroxyl radical producing neurotoxicity. Methamphetamine increases expression of inducible nitric oxide synthase (nNOS)/ neuronal nitric oxide synthase (iNOS ) indicating increased synthesis of neuronal nitric oxide, which combines with superoxide radicals to form peroxynitrite which is a strong oxidant and a major neurotoxin . Induction of nNOS/iNOS by methamphetamine or MDMA  constitutes part of the mechanism of methamphetamine damage, as selective inhibition or genetic inactivation of nNOS and overexpression of cupper zinc superoxide dismutase (CuZnSOD), an enzyme that catalyzes the dismutation of superoxide into oxygen and hydrogen peroxide, prevent methamphetamine neurotoxicity . Even though methamphetamine increases iNOS expression in the striatum , there is no basis for supposing the involvement of glial nitric oxide in methamphetamine-induced toxicity, but it is interesting to note that mice deficient in iNOS have increased resistance to methamphetamine-induced dopamine neuron damage.

methamphetamine

The neurotoxic effects of methamphetamine on the dopaminergic system are accompanied by activation of astroglia and microglia in the same areas  being strongest in the striatum, the area with biggest toxicity. Glial cells are not activated in the nucleus accumbens, which is not much damaged . In mice, glial activation in striatum and in substantia nigra occurs shortly after methamphetamine administration, as indicated by a significant increase in Mac-1 ;a marker of reactive microglia 24 hours after methamphetamine exposure and prominent increases in GFAP ; a marker of reactive gliosis in response to injury occur within a week  after treatment . The extent of these glial reactions correlates with the observed severity of neurotoxicity.

The dopaminergic system is also involved in this toxicity, as demonstrated in various mutant mice in which inactivation of dopamine transport, dopamine D1 receptors or D2 receptors affords a significant protection against methamphetamine toxicity. Administration of THC prevents dopaminergic toxicity after MDMA, a similar amphetamine derivative to methamphetamine, by CB1 receptor stimulation which is present in striatal medium spiny neurons. All these receptors are involved in different aspects of learning processes that became affected by the chronic use of methamphetamine or MDMA.

Finally, Drug abuse, addiction and independence are problems that people grapple with every day. These problems need to be treated effectively through integrative medicine. Dr. Dalal Akoury (MD) is an expert at this.  Call her on (843) 213-1480 for help.

Molecular Mechanisms of Methamphetamine Induced-Neurotoxicity

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Intravenous B Vitamins and the Addiction Disease

Nutrition plays a major role in keeping us safe from diseases of all kinds and even making our bodies able to fight these diseases when attacked. However addiction to certain drugs depletes some of the most crucial vitamins and other important nutritional components that are supposed to make us healthy and be safe from addictions. B vitamins are some of the most important vitamins in our bodies as they are very essential for the proper functioning of our brain and the entire nervous system. Supplements with natural vitamin B can help with drug addiction, stress, and depression. This is because most drugs are suppressants to the nervous system and in the long term they leave the nervous system incapacitated to work efficiently.  Like sated earlier B vitamins are very crucial in our bodies but are often depleted by drug and alcohol use. To show how important B vitamins are let’s look at their roles in our body.

Intravenous B Vitamins

The roles of vitamin B in the body

One of the most important functions of B vitamins in our bodies in relation to addiction is that they can help in fighting addiction.  Vitamin B3 or niacin are an effective bunch in treatment of addiction especially addiction to alcohol as they metabolize alcohol out of your body and regulates part of the stress-related hormones of the adrenal glands. Therefore in case of deficiency in these vitamins an IV supplementation of these vitamins will help. Another serious withdrawal symptom is Insomnia, this can be resolved by Vitamin B6 which is essential in production of the chemical serotonin, which helps in restoring calmness in case of anxiety and depression and also helps in regulation of melatonin levels to induce sleep. Brain is a victim of most drug of abuse, Vitamin B9 is crucial in restoring cellular as well as brain health. researchers have found out that when vitamins B3, B6 and B9 are given intravenously in higher doses they help in reducing alcohol cravings and anxious tension, as well as insomnia and mood fluctuations that are common symptoms of withdrawal.

Other important B vitamins include Vitamin B1 also known as thiamin, and vitamin B2, known as riboflavin. these two vitamins helps in  maintaining cell health by processing nutrients from foods and converting carbohydrates, fats and proteins to usable energy.  Thiamine supplementation is a recommended treatment in alcohol addiction treatment as it helps in reducing fatigue, maintaining mental clarity and decreasing disorientation. Riboflavin helps in reducing the severity of headaches and hand tremors associated with alcohol and other drugs withdrawal.  These two vitamins can be intravenously supplemented in addicts to help them through the withdrawal phase of the addiction treatment. Owing to its importance in the body, it’s better to discuss thiamine in detail.

Thiamine in Detail

Thiamine or Thiamin also known as Vitamin B1 is a water-soluble vitamin of the B complex. This vitamin is needed so that our bodies can use carbohydrates as energy. It is a necessity for glucose metabolism. Thiamine also plays an important role in nerve, muscle and heart function.

Thiamine is found in many foods such as yeast, cereal grains, beans, nuts, and meat. It is part of vitamin B vitamins with which it is often used in making vitamin B complex products. Vitamin B complexes generally include vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin/niacinamide), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), and folic acid.

There are situations when a person will be required to take Thiamine, thiamine deficiency syndromes such as beriberi and neuritis that may arise during pregnancy require supplementation of thiamine. It is also used to treat digestive problems which may include ulcerative colitis, diarrhea and even poor appetite.

This vitamin has many uses, some of its uses include; it is used in vision problems like cataracts, it is also used by HIV patients as an immune booster, used in treating brain damage and in prevention of cervical cancer. It can still be used to enhance learning abilities and to enhance positive mental attitude. It also increases energy and is also useful in preventing memory loss.

Despite its many uses thiamine is widely used in treating a memory disorder known as Wernicke’s encephalopathy syndrome which is common in those addicted to alcohol. Therefore it has been found to be effective in fighting alcoholism which in itself is an indication of thiamine deficiency.

Intravenous B Vitamins

Generally deficiency of B vitamins has been found to be responsible for much of the fatigue, skin irritation, memory loss and depression experienced by people who are newly recovering from an addiction to alcohol. Therefore recovering addicts can benefit from IV B vitamins supplementation. Vitamin B in general, and particularly vitamins B1 , B3  and B5 have a role in ensuring there is enough energy in the cells as they are primarily responsible for turning sugars into energy. B6 and B12 play important roles in producing blood cells and the health of the nervous system. Naturally the B vitamins can be found in foods we eat particularly in pork, nuts, cereals, salmon, grains (whole grains), liver, egg and milk.

As can be seen above the functions of the B vitamins in fighting addiction are numerous and the effectiveness of having an IV B vitamins regimen cannot be underestimate as it is through the restoration of the normal levels of the regimen that we can heal the nervous system and provide the cells with enough energy throughout the addiction treatment and beyond.

Finally, Here at AWAREmed Health and Wellness Resource Center we are committed to availing help to addicts by availing some of the most integrative approaches to healing an addict. We advocate for natural healing to all kinds of addiction. Call on Dr. Dalal Akoury (MD) at Myrtle Beach, South Carolina for help.

Intravenous B Vitamins and the Addiction Disease

 

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