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Acetaldehyde poison and Alcohol consumption

Acetaldehyde poison

Acetaldehyde poison and Alcohol consumption if not addressed in good time can be catastrophic

Acetaldehyde poison and Alcohol consumption: Cytochrome P450 2E1 (CYP2E1)

In light social drinkers nearly all the alcohol consumed is taken care of by alcohol dehydrogenase. However, the enzyme Cytochrome P450 2E1 (abbreviated CYP2E1) becomes quite active in metabolizing alcohol in chronic heavy drinkers. CYP2E1 does its work in the liver. The hydrogen released by this reaction is bound to oxygen and to NADPH to form water and NADP+. This reaction takes energy rather than producing it. CYP2E1 does its work in the microsomes of the cell. This is sometimes referred to as MEOS (Microsomal Ethanol Oxidizing System). CYP2E1 is a member of the Cytochrome P450 enzyme family. The next enzyme is the catalase.

Acetaldehyde poison and Alcohol consumption: Catalase

Catalase is found in tiny organs inside of cells called peroxisomes. Catalase is found all over the human body. When catalase turns alcohol into acetaldehyde the hydrogen which is released is bound to hydrogen peroxide molecules which then become water. Although catalase is active everywhere in the body, catalase is of particular interest to researchers because it metabolizes alcohol in the brain. The acetaldehyde released into the brain by the metabolism of alcohol by catalase has the potential to combine with neurotransmitters to form new compounds known as THIQs (tetrahydroisoquinolines, also sometimes called TIQs). Some researchers believe that THIQs are the cause of alcohol addiction and that the presence of THIQs distinguishes addicted drinkers from social drinkers. Other researches strongly dispute the validity of the THIQ hypothesis of alcohol addiction. The actual role of THIQs remains controversial and calls for further research.

Acetaldehyde poison and Alcohol consumption: How acetaldehyde dehydrogenase works

Acetaldehyde dehydrogenase does its work in the mitochondria of cells and removes a hydrogen atom from acetaldehyde to produce an acetic acid radical. This hydrogen atom combines with NAD+ to form NADH.

There are several varieties of aldehyde dehydrogenase found in the human body. The one which normally breaks down acetaldehyde is called ALDH2. There is another variety aldehyde dehydrogenase found in the human body which is called ALDH2*2. ALDH2*2 is only about 8% as efficient as ALDH2 in metabolizing acetaldehyde. Some East Asian people have ALDH2*2 instead of ALDH2 in their bodies. These individuals find the effect of alcohol to be very unpleasant as we discuss below. Doctor Dalal Akoury MD, President and founder of AWAREmed Health and Wellness Resource Center reiterates that the aldehyde dehydrogenase enzymes are found in many tissues of the body, but are at the highest concentration in the liver

The problem with too much NADH

Finally, it is important to appreciate that alcohol metabolism produces excess amounts of NADH (Nicotinamide Adenine Dinucleotide plus Hydrogen). This excess of NADH can lead to acidosis from lactic acid build-up and hypoglycemia from lack of glucose synthesis. It can also lead to weight gain, fatty liver, and heart attack. It is because of these health risks that made doctor Akoury to formulate this health facility to offer meaningful and professional treatment that yield absolute result. This is not a simple problem and therefore, if you are struggling with alcoholism, help is just a phone call away. As soon as you make that call, an appointment will be schedule and your life will be transformed positively and for real productivity.

Acetaldehyde poison and Alcohol consumption: Cytochrome P450 2E1 (CYP2E1)

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Encouraging alcoholism treatment for health

Encouraging alcoholism treatment

Encouraging alcoholism treatment for health and productivity

Encouraging alcoholism treatment for health: Combined behavioral intervention

Even though we are not ignorant of the consequences of alcohol abuse and drug addiction, many are still hooked into these substances. This is because of their addictive nature which is why prevention is always the best. And while experts at AWAREmed Health and Wellness Resource Center lead by doctor Dalal Akoury MD who is also the founder of the same are creating awareness over the same, we also need to address the direct victims who are already sinking into these habits. Throughout this article, we want to stand out in encouraging alcoholism treatment among other substances of abuse for better health of our children and the next generation to come. And as the name suggests combine behavioral intervention is a collection of various counseling techniques meant to motivate alcoholics to consider turning away from their drinking habits. The various elements could for instance be derived from psychotherapy treatments such as cognitive behavioral therapy, motivational enhancement therapy, and 12-step programs. This will help the addicts to understand the mechanisms for not taking alcohol purposely to achieve and maintain total abstinence.

Encouraging alcoholism treatment for health: Behavioral therapies for partners

According to doctor Dalal Akoury, it is important to note that, treatment for alcoholism will not be successful if only direct victims of alcoholism are treated. Those family members, guardians, relatives and friends caring for their addicted loved ones are equally suffering from the effects of alcoholism. They too needs to be involved in the behavioral approaches to help them understand and cope with their recovering alcoholic partners. Where children are involved then it will be necessary that both parents participate in couple based therapy instead of just administering treatment to the parents with alcoholism.

Encouraging alcoholism treatment for health: Treating sleep disturbances

It is common knowledge that majority of alcoholics also suffer from sleep disorders which may last for months or even years. This condition must be arrested in good time and the following are some of the available therapies in addressing sleep disorders; sleep hygiene, bright light therapy, meditation, relaxation methods, and other nondrug approaches. As a way of finding solution having been encouraged to seek for treatment, we want to bring to your attention that because of the magnitude of the problem on hand, doctor Akoury made a passionate decision of creating this health facility with a primary objective of transforming each individual’s life through increasing awareness about health and wellness and by empowering individuals to find their own inner healing power. This is very essential in treatment and besides, Dr. Akoury’s practice focuses on personalized medicine through healthy lifestyle choices that deal with primary prevention and underlying causes instead of patching up symptoms. I don’t know what is going on in your mind, but one thing is certain that calling doctor Akoury on telephone number 843 213 1480 should be your starting point if you want to live a life that is free from alcoholism and drug addiction.

Encouraging alcoholism treatment for health: Combined behavioral intervention

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Alcohol consumption legality verses the dangers

Alcohol consumption legality

Alcohol consumption legality verses the dangers has become an impediment in the management of alcohol use.

Alcohol consumption legality verses the dangers: Long term effects of heavy drinking

There is no question about the alcohol consumption legality across the globe. Each nation has rules guiding the consumption of this substance. But away from all those rules, it does not delete the dangers that come with alcohol use. What is worrying is that before the formulation of the rules, the dangers are known. And so it is quite unfortunate that alcohol is legal in as much as we are revealing its dangerous effects to human health. One of the control measures put by the authorities is the introduction of age limit. Currently in many nations across the globe the recommended age for drinking is 18 year though in some countries this limit can be up to 19 years or even more. According to the experts at AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury MD, this is one of the most ineffective control as many under age easily get access to this substance. Young people drink at home, in the streets and pubs despite this rule further complicating the dangers attached. Despite all these challenges, we can still do something to be safe from this scourge of alcoholism. If you are struggling with alcohol addiction, you can seek professional assistance from doctor Akoury by calling her today for the commencement of your recovery program.

Alcohol consumption legality verses the dangers: The law about drinking and driving

Many lives are unnecessarily lost on the roads globally due to drink driving. Studies have also established that alcohol is the major cause of many of these deaths and because of these nearly all states across the globe are taking this seriously by enforcing stringent laws to protect and save lives. Drink driving has become a serious criminal offence and driving with blood alcohol content of 0.08 % and above will land you in the wrong books with the authorities. Other general illegalities and penalties include:

  • To drive while impaired even if your BAC is less than 0.08 per cent.
  • Declining to provide a breath sample when asked by the police is also illegal.
  • Suspension of your driver’s license on the spot for 90 days
  • Separate criminal charges to face in court.
  • Also, if you are learning to drive and have a Graduated Driver’s License, you are not allowed to drive after drinking ANY alcohol.

These are just but a few rules and penalties applicable in most countries in an effort to bringing order on our roads. The same penalties and more are also applicable where one mixes alcohol with other drugs. To demonstrate the seriousness of this problem the authorities in Ontario have made even much harsher penalties to offenders. For instance if you are convicted of impaired driving more than once the penalties is as follows:

  • First conviction – your driver’s license is suspended for one year and a further $600 fine.
  • Second conviction – your driver’s license is suspended for three years and 14 days in jail.
  • Third conviction – your license is suspended for 10 years or for life plus 90 days in jail
  • Fourth conviction: such offenders will never own a driver’s license in Ontario soil again and they will still be sentenced to jail for another 90 days.

It look harsh but if this is what will bring serenity on our roads then it is worth it.

Alcohol consumption legality verses the dangers: Long term effects of heavy drinking

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Alcohol kills

Avoiding early death by managing alcohol usage

Avoiding early death

Avoiding early death by managing alcohol usage is very essential for the whole society

Avoiding early death by managing alcohol usage: Drug addiction

Alcohol is not only the number one addictive substance but also number one killer. It leads because it does not only kill its abusers but also very innocent people who have never had the taste of alcohol in their entire life time. The magnitude of alcohol effects are so real and many that researchers have had difficult time determining exactly what are the consequences of drinking this substance which has been associated with causing earlier death. The health complications associated with alcohol consumption include heart attack, diabetes, heart failure and stroke or lung disease further explaining why avoiding early death by managing alcohol usage is such an important topic. According to the experts from AWAREmed Health and Wellness Resource Center under the leadership of doctor Dalal Akoury MD, those who drink regularly are subjecting their life into several risks including:

  • Premature death from injuries, accidents or violence triggered by alcohol consumption.
  • Alcohol overdose may lead to death. The danger is so particular with young people in the adolescence who may want to impress their peers with their ability to drink alcohol and sense of belonging inducing them into taking alcohol even though they may not be able to gauge its effects.
  • Severe withdrawal and delirium tremens. Delirium tremens occurs in about 5% of alcoholics. It includes progressively severe withdrawal symptoms and altered mental states and in some cases, it can be fatal.
  • Frequent, heavy alcohol use directly harms many areas in the body and produce dangerous health conditions like liver damage, pancreatitis, anemia, upper gastrointestinal bleeding, nerve damage, and erectile dysfunction.
  • Alcohol abusers who need surgery have an increased risk of postoperative complications, including infections, bleeding, insufficient heart and lung functions, and problems with wound healing. Alcohol withdrawal symptoms after surgery may impose further stress on the patient and hinder recuperation.

Avoiding early death by managing alcohol usage: Effects of hangover

  • Although not traditionally thought of as a medical problem, hangovers have significant consequences including changes in liver function, hormonal balance and mental functioning and an increased risk for depression and cardiac events.
  • Hangovers can impair job performance, increasing the risk for mistakes and accidents.
  • Hangovers are generally more common in light-to-moderate drinkers than heavy and chronic drinkers, suggesting that binge drinking can be as threatening as chronic drinking.
  • Any man who drinks more than five drinks or any woman who has more than three drinks at one time is at risk for a hangover.

Finally, even though this substance is legally allowed for consumption, it has far reaching effects to human health as stipulated above and more as we are about to find out in our nest posting. Because of this, prevention becomes the best option for safety and that is why we are discussing this topic of avoiding early death by effectively managing alcohol consumption. I need not to tell you of the dangers of being addicted to alcohol because the facts above speaks for themselves. Nonetheless if you or anyone you know is struggling with alcohol addiction, we have some good news of hope for you. Doctor Dalal Akoury and her team of experts from AWAREmed Health and Wellness Resource Center are on standby to help you overcome this addiction. Call now and free yourself from this bondage.

Avoiding early death by managing alcohol usage: Drug addiction

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Career and drugs

Alcohol miss management and its consequences

Alcohol miss management

Alcohol miss management and its consequences can only be a recipe of anarchy

Alcohol miss management and its consequences: Accidents, suicide and murder

Where I come from people make fun when they are taking their cherished drink that “this is time for one for the road”. Let me make it simpler, after treacherous day of work, before you proceed home, you make a stopover for a drink with friends (one for the road). Many who have lavished this slogan have not been obedient to just taking one, but they have wined and drunk they whole pocket dry. In the process a lot of damage have taken place as a result of that slogan and today majority of deaths on our roads are facilitated by drink driving giving alcohol lead role in accidents, suicide, and crime. Does this ring a bell in your mind? It does to me and that brings me to my focus of this discussion ‘alcohol mismanagement and its consequences.” From our point of view as experts from AWAREMED Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury MD, a season like this (x-mass festivities) year in year out registers the most death on our roads globally. Take a look at some of the effects of alcohol;

  • Alcohol plays a major role in more than half of all automobile fatalities across the globe.
  • Alcohol-related automobile accidents are the leading causes of death in young people.
  • When it comes to alcohol we do not have favorable limits for safe drinking because two drinks can impair the ability to drive and even one drink may double the risk of injury, and more than four drinks increase the risk by 11 times therefore the only safe way is not drinking at all.
  • Alcoholism is the primary diagnosis in a quarter of all people who commit suicide.
  • Alcohol is implicated in over half of all murder cases, with this ratio of one to one you can only desire to stop drinking.

Even before we bring it close to your door step the facts above are enough to motivate you to seek for professional help from the experts at AWAREmed Health with doctor Akoury today. Don’t put your life on the line with peer slogan, one for the road because it could be one for the grave.

Alcohol miss management and its consequences: Domestic violence

If you have been to the alcoholic residence, you may have notice the elusiveness of peace and poor or no communication, conflicts and suspicion. The members of such households are not independent and expressive than non-alcoholic households or even recovering alcoholic parents. Domestic violence is a common consequence of alcohol abuse.

Effect on Women – women often are the victims of domestic violence, they incur serious injuries from their male partners who are abusing alcohol

Effect on Children – alcoholism in parents also increases the risk for violent behavior and abuse toward children. Children of alcoholic parents tend to do worse academically than others, have a higher incidence of depression, anxiety, and stress and lower self-esteem than their peers. In addition to their own inherited risk for later alcoholism, many children of alcoholics have serious coping problems that may last their entire life. Adult children of alcoholic parents are at higher risk for divorce and for psychiatric symptoms.

Alcohol miss management and its consequences: Accidents, suicide and murder

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