Tag Archives: Adult stem cell

stem cells

Treatment of Osteoarthritis by Stem Cells and Scaffolds

August 19, 2016

Affecting over 20, 000, 000 Americans, Osteoarthritis remains to be one of the most popular forms of arthritis characterized by a breakdown of joints most commonly in the knees, hips, spine, elbows, ankles and shoulders that might result from stress or an injury.

A functional cartilage of any young adult who is healthy is composed of a matrix that contains a mixture of sugars, proteins, collagen, and water. In the matrix, we have the chondrocytes whose primary purpose is to make the matrix they exist in.

Cartilage can withstand any additional load put on it simply because it can go back to the way it was initially after the load is lifted. Trauma or anything close may damage cartilage. This changes the way it functions. To restore the cartilage back to its normal condition, the chondrocytes begins to involve the devastating enzymes. A series of reactions start to take place such as, the deformation of the bone that is underlying, joint lining and production of cytokines which are protein messengers that work best to stimulate the inflammation.

These processes encourage the cartilage to wear away followed by a deformity as well as chronic inflammation influenced by unusual activities at the joint. To treat osteoarthritis, health experts have involved a series of remedies that involve anti-inflammatory drugs free of steroids, physical therapies as well as injection of hyaluronic acid or corticosteroid to the joints.

 

stem cells

Stem cell therapy has with time gained some popularity for being among the best promising remedies for osteoarthritis as well as its ability to bring back the cartilage to full functionality. However, this doesn’t mean that a one-time stem cell application will do the magic.

There have been several tests that have been carried out to figure out how stem cells can work together with the scaffold to effectively activate regeneration of the cartilage.

Several reviews have targeted to explain the scaffold types that can be put to study. Among them are, biomaterials such as sugars, chitin, the cell walls of algae, silk, fibrin, collagen and more.  Seeded with several growth factors, the scaffolds works nest to stimulate the multiplication and division of stem cells while at the same time shielding them from being destroyed by a harsh environment which is the arthritic joint.

Now, to use autologous stem cells in modern clinical medicine, there is a need to involve fat as a scaffold for the matrix. Together with several growth factors obtained from the components of blood, the matrix activates the certain biometric scaffold as mentioned above.

 

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Stem cell and wellness industry

August 15, 2016

Stem Cell has positively impacted both the wellness as well as health industry. Apart from its initially intended purpose, recent studies have shown that stem cell can also perform best as an anti-ageing ingredient.

To understand how stem cell therapy and wellness industry are connected, it is vital to be well acquainted with the meaning of cell culturing and how it works.

Understanding cell culturing works

Culturing can be simply defined as the ability of medical specialists to obtain and cultivate a single adult cell in a laboratory. The single cell is expected to turn into human adipose cells or fibroblast conditioned media. Many new cells can then be grown from the fibroblast’s progenitor cell that is often obtained from the adipose cells of the humans.

The result is a conditioned media which contain protein secretions from the cells. These proteins are then included in the serums commonly used by health as well as wellness industries around the globe.

Several industries have used the conditioned media of adult cell always to solve several degenerative related complications. Among the most common serum types is the anti-aging serum often intended to eliminate stretch marks, wrinkles, reduce scars as well as reverse several aging signs.

Use of this anti-ageing serum is considered useful by many wellness industries because most aging signs are related to the health of cells in the human body.

 

stem cell therapy

For instance, wrinkles are stimulated by the inelasticity in the cells. The anti-ageing serum works best to replicate new healthy cells as well as stimulate the regrowth of cells that in turn facilitates reduction of aging signs.

Apart from being among the best remedies for aging, serums that are derived from cell culturing have been manufactured to solve several health-related complications such as the formation of blood vessels, prevention hair loss as well as enabling the body to heal faster.

There is also a series of clinical tests that have been carried out to convey the use of serum that is derived from conditioned media. The findings didn’t prove the effectiveness of this type of serum, but there is some evidence that it is highly dependent on adult conditioned media.

Conclusion

Cell culturing, although not fully accepted by many ethically-minded researchers, has impacted both the wellness as well as the health industry.

Apart from bringing new effective serums into the market, it has also encouraged several studies intended to bring out the new approaches to the production of potentially useful anti-ageing solutions. It is apparent that the researchers are more into maximizing the benefits of cell culturing with an aim of improving the performance of medical industries.

 

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dental pulp stem cells

Understanding How Dental Pulp Stem Cells Use and Banking Works

July 19, 2016

Dental pulp can simply be defined as the soft living tissue that exists inside your tooth. These soft tissues contain stem cells that are known as DPSCs. Just like any other stem cells, DPSCs have the ability to become any cell in human body.

Among the best functional Dental Pulp Stem Cells can be obtained from the baby’s milk teeth either on the lower or the upper incisors and canines. Studies have shown that this kind of stem cells can also be found in the wisdom tooth of a young adult.

Dental Pulp Stem Cells can be likened to mesenchymal cells known to be quite beneficial in various treatments. These cells can differentiate to form different types of cells in the body that includes, osteoblasts, adipocytes as well as chondrocytes.

Potential Uses of Dental Pulp Stem Cells

Dental Pulp Stem cells are among the vital requirements in regenerative stem cell therapies of several degenerative related complications. They offer a variety of potential therapeutic applications that include.

  • Myocytes: Muscle tissue repair
  • Neuronal: Brain and nerve tissue regeneration
  • Adipocytes: Fat tissue generation
  • Chondrocytes: They can generate and regenerate cartilage vital for joint injuries and arthritis treatments.
  • Osteocytes: Generation of Bones

In summary, dental pulp stem cells have the ability to generate some structures in the body that include bone, cartilage, dental tissue and more.

Understanding Dental Pulp stems cell harvesting

Stem cell harvesting is simply a procedure that involves the collection, storage as well as the preservation of Dental Pulp Stem cells. To maintain their nature, DPSCs have to be frozen and kept inside a stem cell bank. This requires the use of cryopreservation technology that maintains the stem cell’s variability. Here is the procedure.

dental pulp stem cells

Stem Cell Harvesting Steps

  1. Collecting of the cells: Here a dentist will extract the tooth from the donor and store it in a kit. The dentist will then send to the facility to be processed.
  2. Separating the stem cells from the dental pulp: Here the stem cells will be obtained from the dental pulp by crushing the tooth to access the cells. The cells will then be checked for sterility as well as quality.
  3. Preservation of the stem cells: If the stem cells make it past the viability test they will be preserved cryogenically. The cells will be frozen at a temperature of -238 F.

Advantages of Dental Pulp Stem Cell Banking

  1. Dental Pulp Stem Cells banking period is wide. It will work best for kids aged between 5 to 12 years as well as the seniors whose wisdom tooth is to be extracted.
  2. The collection from the dental pulp is easy, quick, effective and painless and the best part has no risks.
  3. Dental Pulp Stem cells have no controversies surrounding their use unlike what we see with the embryonic stem cells.
  4. They have also proven to be interactive with biomaterials putting them among the best choices for tissue repair.

The bottom line

Currently, several debates are revolving around the procedure behind stem cell application. There are ethical issues that give the proponents a hard time explaining why the world needs it. Using Dental Pulp Stem cells, on the other hand, is simple, safe and the best part, free of ethical issues.

 

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stem cell tissues

Stem Cell Therapy versus Traditional Medicine

July 17, 2016

Organic regeneration and stem cell tissues in traditional medicine

Studies have shown that stem cells can be harvested directly from the adipose tissue to regenerate diseased organs. According to traditional medicine, this practice is abnormal. It means that the human body can heal itself. According to Tibetan traditional medicine, these mechanism is based on energy meridian which is coordinated by the brain’s primordial energy.

Human brain controls each and every psychological process in the body, and this includes differentiation and specialisation of stem cells to regenerate and heal tissues of the affected organ.

The energy barriers are removed if the acupoints located along the meridians are stimulated. This action also sends signals to the brain informing it about the presence of a dysfunctional in the organ. The brain will then analyse the information submitted through energy impulse and then orders the repair system to harvest the required number of stem cells from your body.

This system will then specialise the stem cells as required and send them to the dysfunctional organ. Once they reach the sick body, they begin the regeneration process as well as the elimination of non-functioning cells.

This aspect is vital just because, whenever the organ gets an injury, the body reacts to send genetic information to the stem cells. So, it is important that the stem cells targeted are distinguished with proper genetic information.

stem cell tissues

Tissue regeneration process takes place throughout the body. Several acupoints that coordinate several body functions are stimulated by an acupuncture period. This enables removal of cell residues as well as toxins from the organs restoring their structures.

There are several applications of this stem cell procedure that includes aesthetic as well as medical. But the result depends on the capacity with which your body regenerates. For example, the rate at which an organ is cured depends on the functionality of the tissue involved.

Benefits of stem cell therapy in traditional medicine

This remedy is applicable for both adults, kids as well as pregnant women. Use of stem cell therapy in traditional medicine treatment comes with several benefits that include.

  1. It brings the cell activity to equilibrium and works well to detoxify the organic environment. Studies have shown that the cells obtained from the body of a sick person function best in an artificially made natural surroundings that are clean. When inserted in the body of a sick person, the processes of the cells decrease invariably.
  2. Regeneration and revitalization of the organs, blood as well as skin. The procedure applies to all sorts of chronic illnesses that includes anaemia, leukaemia, cancer, Benin tumours, diabetes mellitus, prostate adenoma, pituitary adenoma, hepatitis, fibroma, bone marrow diseases and more.
  3. It strengthens your osseous system and tones your muscles: This treatment work for muscular dystrophy and paralysis, backbone diseases and more.
  4. It also reduces the effects of ageing as well as prevention of particular illnesses such as osteoporosis and many others.

After a few findings on the limits involved in this therapy, it has been realised that stem cell therapy is applicable for both modern medicines as well as traditional medicine.

 

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Stem Cell Therapy: Frequently Asked Questions

July 16, 2016

Stem Cell Therapy is characterised by controversies that emanate from several contra-findings. Currently influenced by political debates, it is hard to know what’s true and what is not. Here are some of the frequently asked questions about the topic.

1.    What is stem therapy?

Stem cell therapy is simply a procedure that involves the use of blank state cells to regenerate damaged tissues in both humans and animals. These empty state cells can change to other cells that include, bone, muscle, nerve as well as organ cells.

This gives them the ability to regenerate tissues that are damaged vital for treatments of several complications such as spinal cord injury, osteoarthritis, degenerative disc, motor neurone disease and many others.

2.    Is it legal to use embryonic cells?

Yes, it is legal. However, funding by federal governments only targets research that follows strict guidelines. It isn’t wrong to go beyond these guidelines, but doing this will be excluded from federal funding. President Obama tried to loosen these restrictions in 2009 without success.

According to law, research that involves creating new stem cell lines can receive federal funding. This means that carrying out the research outside the guidelines will require the organisation concerned to find its way of funding it.

3.    What is the response of proponents to embryonic stem cell criticism?

Proponents claim that destroying an embryo after extraction of stem cells isn’t unethical as it is claimed to be. This is because the embryo is often destroyed when the donor no longer needs them to reproduce.

When done with the embryos, the donors have an option of killing the ones left, donating them to other women in need of it or donating them to science. The embryos used in this procedure are the ones that were to be destroyed.

stem cell therapy

4.    Are there any other kinds of stem cell therapies?

Yes. There are other types of stem cell therapies that don’t use embryonic cells. Stem cells can also be obtained in other places that include, adult umbilical cords, bone marrow as well as blood. It has also been noticed that healthy human cells can also be engineered to function the same way.

  1. What is the reason of going on with the embryonic stem cell research that is controversial if the cells can be obtained from adults?

Unlike, adult cells, embryonic cells aren’t limited. Embryonic cells have the ability to become any other cells in the human body. Adult cells aren’t also dependable when it comes to creating new motor neurones. However, they can successfully work for replacing the spinal disc, bone tissue, cartilage or muscle.

6.    What are the risks associated with this therapy?

Currently, the research that has targeted the therapy is still shallow. However, it has been noticed that the practice can increase the risks of cancer in patients receiving the treatment. Cancer results from cells that multiply faster and cannot self-destruct even when something goes wrong.

Stem cells, on the other hand, stimulates rapid multiplication of cells, and they tend to be a little hesitant when it comes to self-destruction.

 

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