Intravenous B Vitamins and the Addiction Disease

March 12, 2015

Nutrition plays a major role in keeping us safe from diseases of all kinds and even making our bodies able to fight these diseases when attacked. However addiction to certain drugs depletes some of the most crucial vitamins and other important nutritional components that are supposed to make us healthy and be safe from addictions. B vitamins are some of the most important vitamins in our bodies as they are very essential for the proper functioning of our brain and the entire nervous system. Supplements with natural vitamin B can help with drug addiction, stress, and depression. This is because most drugs are suppressants to the nervous system and in the long term they leave the nervous system incapacitated to work efficiently. Like sated earlier B vitamins are very crucial in our bodies but are often depleted by drug and alcohol use. To show how important B vitamins are let’s look at their roles in our body.

Intravenous B Vitamins

The roles of vitamin B in the body

One of the most important functions of B vitamins in our bodies in relation to addiction is that they can help in fighting addiction. Vitamin B3 or niacin are an effective bunch in treatment of addiction especially addiction to alcohol as they metabolize alcohol out of your body and regulates part of the stress-related hormones of the adrenal glands. Therefore in case of deficiency in these vitamins an IV supplementation of these vitamins will help. Another serious withdrawal symptom is Insomnia, this can be resolved by Vitamin B6 which is essential in production of the chemical serotonin, which helps in restoring calmness in case of anxiety and depression and also helps in regulation of melatonin levels to induce sleep. Brain is a victim of most drug of abuse, Vitamin B9 is crucial in restoring cellular as well as brain health. researchers have found out that when vitamins B3, B6 and B9 are given intravenously in higher doses they help in reducing alcohol cravings and anxious tension, as well as insomnia and mood fluctuations that are common symptoms of withdrawal.

Other important B vitamins include Vitamin B1 also known as thiamin, and vitamin B2, known as riboflavin. these two vitamins helps in maintaining cell health by processing nutrients from foods and converting carbohydrates, fats and proteins to usable energy. Thiamine supplementation is a recommended treatment in alcohol addiction treatment as it helps in reducing fatigue, maintaining mental clarity and decreasing disorientation. Riboflavin helps in reducing the severity of headaches and hand tremors associated with alcohol and other drugs withdrawal. These two vitamins can be intravenously supplemented in addicts to help them through the withdrawal phase of the addiction treatment. Owing to its importance in the body, it’s better to discuss thiamine in detail.

Thiamine in Detail

Thiamine or Thiamin also known as Vitamin B1 is a water-soluble vitamin of the B complex. This vitamin is needed so that our bodies can use carbohydrates as energy. It is a necessity for glucose metabolism. Thiamine also plays an important role in nerve, muscle and heart function.

Thiamine is found in many foods such as yeast, cereal grains, beans, nuts, and meat. It is part of vitamin B vitamins with which it is often used in making vitamin B complex products. Vitamin B complexes generally include vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin/niacinamide), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), and folic acid.

There are situations when a person will be required to take Thiamine, thiamine deficiency syndromes such as beriberi and neuritis that may arise during pregnancy require supplementation of thiamine. It is also used to treat digestive problems which may include ulcerative colitis, diarrhea and even poor appetite.

This vitamin has many uses, some of its uses include; it is used in vision problems like cataracts, it is also used by HIV patients as an immune booster, used in treating brain damage and in prevention of cervical cancer. It can still be used to enhance learning abilities and to enhance positive mental attitude. It also increases energy and is also useful in preventing memory loss.

Despite its many uses thiamine is widely used in treating a memory disorder known as Wernicke’s encephalopathy syndrome which is common in those addicted to alcohol. Therefore it has been found to be effective in fighting alcoholism which in itself is an indication of thiamine deficiency.

Intravenous B Vitamins

Generally deficiency of B vitamins has been found to be responsible for much of the fatigue, skin irritation, memory loss and depression experienced by people who are newly recovering from an addiction to alcohol. Therefore recovering addicts can benefit from IV B vitamins supplementation. Vitamin B in general, and particularly vitamins B1 , B3 and B5 have a role in ensuring there is enough energy in the cells as they are primarily responsible for turning sugars into energy. B6 and B12 play important roles in producing blood cells and the health of the nervous system. Naturally the B vitamins can be found in foods we eat particularly in pork, nuts, cereals, salmon, grains (whole grains), liver, egg and milk.

As can be seen above the functions of the B vitamins in fighting addiction are numerous and the effectiveness of having an IV B vitamins regimen cannot be underestimate as it is through the restoration of the normal levels of the regimen that we can heal the nervous system and provide the cells with enough energy throughout the addiction treatment and beyond.

Finally, Here at AWAREmed Health and Wellness Resource Center we are committed to availing help to addicts by availing some of the most integrative approaches to healing an addict. We advocate for natural healing to all kinds of addiction. Call on Dr. Dalal Akoury (MD) at Myrtle Beach, South Carolina for help.

Intravenous B Vitamins and the Addiction Disease

GABA Metabolism in the CNS in Addiction

February 14, 2015

GABA Metabolism in the CNS in Addiction

What is GABA?

Known as Gamma-Amino Butyric acid, it is an amino acid that performs functions of neurotransmitters in the brain.it is the most abundant neurotransmitters occurring in the central nervous system (CNS).it acts as an inhibitor of transmissions in the brain thus in the process calming down activities in the nervous system. It is found as a supplement in which it acts as a natural tranquilizer. It has been shown to increase levels of human growth hormones thus is very popular among body builders.

The Neurotransmitters Question

The brain is made up of millions of cells. Communication takes place from one brain region to another through neurotransmitters. Neurons are individual cells of the nerves that make up the nervous system. They serve as the wiring for the body to transmit information form one region to another. The electrical signals generated are transported through the neurons as a single impulse. Ones the impulses reaches the end of the neurons, it is transmitted to the other cell through neurotransmitters.

The central nervous system consists of the spinal cord and the brain. The two consist of neurotransmitters which pass from one end of the neuron to another. The peripheral nervous system which is made up of nerves that run to the rest of the body. The nerves transmit chemical signals from one neuron t adjacent gland cells and muscles.

GABA and glutamate are the most abundantly occurring neurotransmitters in the nervous system. The two are in abundance in the cerebral cortex which is the region where interpretation of sensation takes place and thinking occurs. The ending of the neurons are made up of sac like structures which are filled with neurotransmitters.

GABA

When the chemical and electrical signals reach the end of the neurons, they trigger the sacs to release neurotransmitters to act as a bridge between one nerve cell and another. The spaces called synapses act as a bridge through which signals pass to the other cells. On reaching the other neuron, the neurotransmitters attach to the cell receptors. This triggers the electric impulse to move from the end of the nerve cell neuron to the other cell completing the message transmission and triggering and effect.

Role of GABA In the Brain

It is formed in the cells of the brain from glutamate. GABA acts as an inhibitory neurotransmitter which simply means that it blocks nerve impulses in the brain. On the other hand, glutamate from which GABA is formed is an excitatory neurotransmitter. When it binds to cells adjacent to it, it activates them to send impulses throughout the brain from one cell to another. GABA instead of telling the brain to activate and send impulses, it tells it he opposite. It stimulates the brain not to send nerve impulses from one cell to another.

In the absence of GABA nerve cells tend to activate more often sending signals regularly. Disorders associated with anxiety such as headaches, addiction, panic attacks, Parkinson syndrome, cognitive impairment and seizures are all linked to low activity of GABA.

It naturally hinders nerve impulses transmission from one cell to another. It brings about a calming effect in the process. The best way to understand the significance of GABA is by understanding the effects of caffeine on the brain. Caffeine acts as an inhibitor of the release of GABA. When the levels of GABA are low in the brain, more nerve transmissions take place. This leads to the sensational feeling that one gets when they takes coffee. This feeling is as a result of activity of glutamate with less GABA.

The reason why, caffeine does this is simply because other molecules tend to bind with the neurons near the site where GABA binds with these neurons. This is exactly the way that basic tranquilizers like barbiturates and Benzodiazepines work. They increase the effects of GABA in the body which in turns inhibits the transmission of nerves.

GABA Metabolism

It is synthesized in a metabolic path known as the GABA shunt. The first step in GABA formation uses a-ketoglutarate that is formed from metabolism of glucose in the Kreb’s cycle. Afterwards a-ketoglutarate is processed by a-oxoglutarate to form glutamate. In the final process, the glutamate undergoes decarboxylation to form GABA through the glutamic acid decarboxylase enzyme. Like other neurotransmitters, GABA is stored in the synaptic vesicles of the brain and is only released when depolarization of the presynaptic membrane takes place.

GABA

GABA and Addiction

Alcohol consumption leads to loss of coordination of the motors as well as sedation as other high levels of inhibitory transmitters do. Studies therefore show that GABA effects contribute to some effects of alcohol in the brain. Past studies show that, GABA as an inhibitory neurotransmitter is affected by alcohol consumption. Continuous alcohol consumption leading to addiction lead to decline in GABA receptors found in the brain and his reduces the ability of the neurotransmitter t bind with cell receptors.

In this case, the body is forced to find ways to compensate for the declined levels of GABA neurotransmitters. These effects are responsible for brain function changes that lead to things like dependence and alcohol tolerance. When one withdraws from alcohol, the stimulating effects on the neurotransmitter disappear. The body has very few GABA receptors needed to balance the effects of excitatory neurotransmitters. Because of this the brain has too many excitatory nerve signals being transmitted. This translates to psychological and physical effects of alcohol addiction and withdrawal.

Dr. Dalal Akoury has years of experience with patients of addiction and other health conditions. This enables her to provide wise counsel to patients who may be going through certain health conditions. Many of these patients have gotten better and they now bear witness to her god works. To become part of this community and to receive regular health and awareness tips that will befit you, visit www.awaremednetwork.com today.

GABA Metabolism in the CNS in Addiction

Restoring Dopamine and Serotonin Levels after Opioid Abuse

January 19, 2015

How to Naturally Increase Dopamine and Serotonin Depleted By Opioid Abuse

Opiates are fancied for their euphoric feelings; they affect the normal production of brain chemicals. At the beginning they may induce a sudden hike in the production of feel good brain chemicals, however when you have used the drugs for some time they will lead to depletion in the levels of the brain chemicals such as serotonin and dopamine. In the brain the production of neurotransmitter happens naturally without intervention of any other drug. These basic neurotransmitters include; dopamine, serotonin, GABA, acetylcholine. The body also produces other chemicals known as endorphins which work as the body’s own opiates functioning to fight pain naturally.

These neurotransmitters have specific functions that they accomplish in the body. Each function is important and works in conjunction with the functions of the other neurotransmitters to make life what it ought to be. These functions are; Serotonin regulates sleep and appetite, Acetylcholine for processing information and memory, GABA acts as your calming neurotransmitter while dopamine is the feel good chemical, plays an important role in mood, energy, attitude, motivation.

When you use these drugs of pleasure thy hike the levels of dopamine in the brain beyond the accepted levels. This will force the brain to find a means by which to suppress the production of the neurotransmitter that has been hiked by drug use. naturally, the production of dopamine will be reduced by the brain after sensing that the hike in the levels of dopamine is caused by factors out of the body, therefore when a person who has been using drugs stops using them, the levels of dopamine and serotonin will be too low below the normal levels and this beckons such feelings of depression, anxiety, nervousness and lack of interest in everything.

Some natural ways to increase dopamine after opiates use

Healthy Eating– good nutrition goes a long way in increasing the levels of serotonin and dopamine. you can eat the following foods to help you in this noble cause; foods rich in carbohydrates, vegetables, whole grains, whole grain pasta, rice, broccoli, spinach, lettuce among other healthy foods. Eating fat processed foods will do the opposite. You may also eat sweet foods like chocolate, only a couple squares of good quality chocolate with a high percentage of Cocoa in it can raise these chemicals. Serotonin is naturally occurring in foods like pineapples, bananas, nuts and plums. You can also get an adequate supply of B vitamins, folic acid and vitamin C because these vitamins play a role in transmitting brain chemicals. Spicy foods like chili peppers and jalapenos. The heat triggers the release of endorphins, so the spicier the better. You may get help from a nutritionist who may give you a list of foods that may be of benefit.

Meditation- through meditation the fatigue in the nervous system is mitigated and so their performance is enhanced. Doing meditation right helps in production of serotonin and endorphins at required levels. At AWAREmed Dr. Dalal Akoury will help you achieve this.

Herbal supplements – Some herbs like St John’s Wort, 5-HTP and L Tyrosine can all increase serotonin and dopamine in the brain, thus easing withdrawal symptoms and shortening withdrawal duration after use of opiates.

Exercise – The benefits of exercise has been echoed by many doctors. It has been applauded as one of the best natural ways to produce serotonin, dopamine and endorphins. However, vigorous exercise is recommended over light exercise that most people seem to enjoy. This is because the stronger the physical demand you place on your body, the greater the release of endorphins. You should try weight training and high and low intensity exercises. Hit the gym and reap big.

Music – Music is good for emotional relief and energy. A person who is suffering from opiate withdrawal symptoms is more sensitive to touch and sound. Listening to good music can help his body to get the brain chemicals work again and boost his moods. Even with different tastes music therapy offers a natural relief from opiate withdrawal.

Sex – sex is helps in boosting the endorphins. A long session can dramatically increase endorphins. When you’re in withdrawal sex can be a very nice escape.

Acupuncture – acupuncture increases circulation and stimulates the release of endorphins. If you haven’t looked into acupuncture while in withdrawal you might want to try it out, it can be very helpful during healing.

Massage – During a massage the release of endorphins get stimulated. Massaging your own scalp and shower massager’s can provide an affordable alternative to expensive treatments. Massage therapy has been used for centuries to help heal certain diseases and its application here may really help you.

Serotonin Laughter – Laughter is a good way to release endorphins naturally. By Watching a good comedy movie or have a laugh with friends you will stimulate the release endorphins which are helpful in the long run.

Sunlight – bright light increases the production of Serotonin in the body. Basking in the sunlight can absolutely improve your mood and also soothe muscle aches. In case there is no sunshine you may use tanning beds which may also help greatly.

There might be other ways of improving the production of these crucial neurotransmitters in the body. But these natural ways above are simple and inexpensive and so can apply to anyone. The bottom line is that by boosting the production of these neurotransmitters you will make it easier for yourself to recover from opiate addiction. However, these problems need to be treated effectively through integrative medicine. Dr. Dalal Akoury (MD) is an expert at this. Call her on (843) 213-1480 for help.

How to Naturally Increase Dopamine and Serotonin Depleted By Opioid Abuse

Are there any Remedies for Serotonin Disturbances And Addiction Treatment?

August 12, 2014

Natural Remedies For Serotonin Disturbances And Addiction Treatment

What is serotonin?

This is a chemical which acts as a neurotransmitter. It helps in relays of signals from one region of the brain to the other. Serotonin is normally created from a biochemical conversion process in which it combines tryptophan, a protein component, with tryptophan hydroxylase which is a chemical reactor. When combined together they form 55-hydroxyltryptamine (5-HT), the substance which is also referred to as serotonin. This compound is sometimes considered to be a hormone, though looking at its functionality it actually reassembles a neurotransmitter.

Where does serotonin originate?

Serotonin is normally manufactured in the brain and in the intestines. It can be found in platelets and the central nervous system though majority of them are found in the gastrointestinal tract. It is important to note that serotonin cannot cross the blood-brain barriers and hence the serotonin that is used in the brain must be produced from within the brain.

serotonin syndrome

Serotonin is believed to be an important chemical that plays role in the body psychological functions such as mood and social behavior, sleep, memory, sexual desire among many others.

What causes serotonin syndrome?

This is a potentially serious drug interaction which occurs due to excessive accumulation of serotonin in the brain. This condition usually occurs when a given medication is started or increased. In most cases it occurs when two medications are taken together.

Normally, serotonin is produced by mind to help in regulation of activities such as digestion, blood flow, breathing and body temperatures. Medication that is normally prescribed to the addicted persons especially those intended to treat depression, pains, headache etc. if taken together they have been proven to cause this condition. Due to these side effects, we need to use more friendly methods in the treatment of addiction as well as when restoring serotonin.

What are the natural remedies for serotonin syndrome?

The natural ways of increasing the levels of serotonin and hence causing balance and treating the symptoms of serotonin can be achieved naturally by use of supplements. There are a number of supplements which through researches have been proven to work effectively in the increasing of serotonin levels in the body. Let’s now look at some of these supplements:-

5-HTP – our bodies manufactures 5-hydroxytryptophan (5-HTP) from tryptophan and then converts it into serotonin. A supplement of this compound can be taken directly into the body in the form of 5-HTP. This supplement is absorbed into the body easily and is able to cross the blood-brain barriers unlike serotonin, and where after crossing the barriers it gets converted into serotonin. 5-HTP has been confirmed clinically to have stronger serotonin support than the other related compound, (L-tryptophan). It can therefore be very effective in the treatment of sleep disorders, depression as well as eating and panic disorders.

How is it taken? This supplement works best when taken while the stomach is empty between 3:00 – 4:00pm and again during bedtime. The dose should be started at low, preferably at 50mg and then gradually increased with time, until the point that is most appropriate.

L-Tryptophan – this is an amino acid which is required by the body in the process of synthesizing serotonin. Conversion of L-tryptophan to serotonin is a two-step process and in the process, 5-HTP is synthesized as an intermediate step. When L-tryptophan is used as a supplement, it enhances the synthesis of serotonin and also increases the levels of serotonin in the body. This supplement is generally considered to be gentle on the body than 5-HTP. It has been therefore used in the treatment of un-depressed, healthy people to be able to process information in a more positive way.

serotonin syndrome

How is it administered? Since this is a more light supplement than 5-HTP, its dosage is higher than that of 5-HTP. For optimum dosage, 3000 to 6000mg of the supplement is recommended per day. Just like with 5-HTP, the supplement best works when taken while the stomach is empty and thus it should be taken when one has not taken food for the previous one or two hours. The dosage can be incremented but this change must be gradual starting from a low dose.

SAM-e – this refers to S-edenosyl methionine, which is produced from amino acids. It is present in all the body cells and it is an essential component in many reactions. One of these reactions in which it is required is in the synthesis of serotonin. This supplement has been used for over 30years in the treatment of depression.

Saint John’s Wort – this is a natural medication which is obtained from an extract of the plant know as Saint John’s Wort. The extracts of this plant are known to exert their anti-depressant actions through inhibition of the reuptake of serotonin as well as norepinephrine and dopamine. This makes more of neurotransmitters available in the brain. This play an important role in the well-being of the person.

How is it administered? Just like the other supplements it works better when taken with the stomach empty. The optimal dosage rate per day is 600 – 1200mg, of the standardized herbal extract which contains around 0.3% hypericin.

Natural Remedies For Serotonin Disturbances And Addiction Treatment

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