Marijuana withdrawal Definitive Symptoms

September 18, 2014

Marijuana withdrawal Definitive Symptoms Cannabis withdrawal involves at least two psychological and one physiological symptom

Marijuana withdrawal

Marijuana Cannabis withdrawal involves the experiencing of at least two psychological and one physiological symptom after ceasing heavy and prolonged use of marijuana. Some psychological symptoms are being Irritable, Anxiety, Depressed mood, being Restless, insomnia, reduced appetite and weight loss. Physical symptoms include abdominal pain, shaking, fever and headaches. These withdrawal symptoms cause a person to be distressed and interference with school, work, or any other daily responsibilities. Many cannabis users agree that withdrawal symptoms make it difficult for them to quit or have contributed to relapse. Most symptoms normally begin within the first 24–72 hours of cessation, peaking within the first week, and lasting approximately 1–2 weeks. Sleep difficulties may last more than 30 days. However, Withdrawal tends to be more common and severe among adults, mostly because of the more persistent and greater frequency and quantity of use among adults.

Marijuana screening

A lawful and effective detection for cannabis can take lots of time, and tests cannot define an exact degree of impairment. Nevertheless, The focusses obtained from such analyses be helpful in differentiating between active use from passive publicity, time since use, and the degree or period of use. The Duquenois-Levine test is normally used as a screening test in the field, but it cannot confirm the existence of cannabis, as a large variety of substances have been shown to provide false positives. The Duquenois–Levine test is a modest chemical color reaction test originally established in the 1930s by Pierre Duquénois. these tests involve a police officer breaking the seal of a tiny micropipette of chemicals, and placing an element of the assumed substance; should the chemicals turn purple, this shows the prospect of marijuana. The color variations can however be subtle, and readings can also vary by the surveyor.

Cows Score Withdrawal(Clinical Opiate Withdrawal Scale)

Marijuana intake before and during treatment decreased the patients score on the Clinical Opiate Withdrawal Scale (COWS) According to the Thomas Jefferson University study .This measure is used to accurately define withdrawal symptoms in opiate-dependent patients. The lesser scores specify that cannabis plays a part in decreasing the symptoms of opiate withdrawal.

DSM-V Criteria And Its Relevance In Marijuana Dependency

(DSM-V) also known as Diagnostic and Statistical Manual of Mental Disorders is used to eradicate the disease kinds for substance abuse and dependence and swaps it with a new “addictions and related disorders”

Eradicating the kind of dependence helps in better distinguishing between the compulsive drug-seeking behavior of addiction and ordinary responses of tolerance and withdrawal that some patients experience when using prescribed treatments that affect the central nervous system, Also new to the DSM-V are diagnostic criteria for “cannabis withdrawal,”. Outcomes in “clinically important distress or impairment in social or any other essential areas of working,” and is characterized by at least three of these symptoms: anger, aggression, irritability, anxiety or nervousness; insomnia, decreased appetite or weight loss; restlessness, sweating, fever, chills, and headache.

Screening

Quantity and frequency of joints per day

There is no known comparable portion of cannabis consumption, possibly due to encounters such as varied joint size, tetra hydro cannabinol content, and ways of delivery Cannabis-related problems, measured by smoking, the alcohol and Substance Connection Screening Test, were foreseen from cannabis use frequency and quantity controlling for gender and age. This sample included 665 participants between the age of 15-67. Cannabis use occurrence and quantity were clearly linked with cannabis-related difficulties. People who smoked cannabis daily were at the highest risk of problems. Controlling for occurrence, the effect of quantity remained important for disappointment to do what is expected due to cannabis use. Research advises that quantity, above and beyond frequency, is a vital predictor of cannabis problems

Urine THC can last weeks after stopping

Cannabis use can often be detected up to 5 days after exposure for people who don’t use it often but up to 15 days for people who use it heavily. People with high body fat can last up to 30 days^[, an occasional or on-off user would be very unlikely to test positive beyond 3–4 days since the last use and a chronic user would be unlikely to test positive much beyond 7 days. The maximum likely times are 7 days and 21 days, in that order. In extraordinary circumstances of extended marijuana use, detection times of more than 30 days are possible in some individuals. Nevertheless, one needs to remember that every person is different, and exposure times can vary due to other factors. Cases^]Common known pharmaceutical drugs which cause false positives in instant THC dip tests include: Ibuprofen, Dronabinol, ketoprofen e.t.c

“Spice” can be wide variety of substance

The word ”Spice” refers to a extensive variety of herbal mixtures that produce know-hows comparable to marijuana (cannabis) and that are labelled as “safe,” legal alternatives to that drug. Usually dispensed or sold under several names, including K2, fake weed, Yucatan Fire, Skunk, Moon Rocks, among others — and also usually labeled “not fit for human consumption” — these products usually comprise of some dried, shredded plant material and chemical spices that are accountable and responsible for their psychoactive (mind-altering) Labels on Spice products often claim that they contain “natural” psycho-active material taken from a variety of plants. Spice products do contain dried plant material, but chemical analyses show that their active ingredients are synthetic (or designer) cannabinoid compounds. Another selling point is that the chemicals used in Spice are not easily detected in standard drug tests.

Marijuana withdrawal Definitive Symptoms Cannabis withdrawal involves at least two psychological and one physiological symptom

THC on Neurodevelopment of Fetuses

September 17, 2014

Long Term of THC on Neurodevelopment of Fetuses

The most vulnerable state in a woman’s life is during pregnancy. This is because at this time she not only has one life to take care of but also another young life that is even more vulnerable. This therefore calls for caution. A woman who is pregnant should be wary of what passes through her mouth and proceeds right into her body. This is because whatever she eats can either make her gestation period and life after a healthy affair or a nightmare. More often than note the life behaviors of a pregnant mother impacts on the life of the foetus as well and therefore it is important for a pregnant woman to distance herself from all drugs and other risky life choices that may impact negatively on the life of her offspring. Just as good nutrition and clinical visits are emphasized to pregnant women it is also good to encourage these women to stay away from harmful drugs like cocaine, bhang and even alcohol. Unfortunately pregnant women have not seen the need to quit indulging in these risky behaviors even when they are expectant. If current research findings are to be believed, about 4% of women in the USA use illicit drugs while pregnant. Seventy five percent of these cases report the use of marijuana. Despite the widespread use of this product, the public is not aware of the potential neurobehavioral effects of this drug on the fetus or the newborn infant. Tetrahydrocannabinol (THC) is the most effective compound found in cannabis sativa. Unfortunately it is effective for all the wrong reasons as it affects the neurodevelopment in fetus and newborn infants. Needless to say it has been used in few doses to avoid nausea and vomit in cancer patients. It has also been used to increase appetite in patients but when used for non medical reasons nothing good can come out of this compound.

THC

Effects of cannabis during pregnancy

Recent studies have proved that children who are exposed to marijuana prenatally encounter such problems as social and cognitive disturbances. One of these study suggested exposing children to heavy marijuana use prenatally increased the risk of giving birth to low weight babies and the reduced head circumference in teenagers is a proof to this argument. It is also exposing fetus to heavy marijuana use prenatally increased the risk of childhood leukemia. Exposing fetus to heavy use of marijuana prenatally also resulted in both long term and short term memory loss. Even as the infants grow into youths they become very poor in judgmental skills and mostly become very slow in learning and adopting new ideas.

In another study, 42 postmortem fetal brain samples from pregnant women at mid gestation (between 18 – 22 weeks old) who voluntarily underwent saline induced abortion, a decrease in dopamine receptor (D2) mRNA expression in amygdala with significant prevalence in male fetuses. 7 Extensive marijuana exposure in utero was associated with the lowest reported mRNA levels. However this study did not show whether this change is transient or permanent but still it was able to prove that exposure to heavy use of marijuana resulted in low mRNA levels.

Effects of Cannabis during breast feeding

When a woman continues to use marijuana, the THC compound in it will not quit causing the side effects it is known for to this infant but will still continue to hurt the life of the infant. The compound will not stay in the mother alone but will be passed to the infant when breast feeding since it is secreted in milk. This may cause side effects in the life of the infant as it will be absorbed and retained in the body of the infant. Researchers opine that at the point of intake into the infant the proportions of the dangerous compound in the milk is minimal to cause any clinical problems but it is sufficient enough to cause serious long-term effects in the infant. It may take time but in the end it affects the neurobehavioral functioning of an infant .Infants exposed to marijuana through breast milk will test positive in urine screens for about 2-3 weeks. One study of 16 women indicated decreased plasma levels of prolactin especially in the luteal phase of the menstrual cycle.

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THC decreases IQ in children

When you are pregnant but you choose to indulge in using marijuana during your pregnancy be sure to have a child that is not very well upstairs. The exposure of a child to THC prenatally will decrease their Intelligence Quotient. This problem affects the teens as that is the period that they try to accomplish things by themselves. Most of the dangers that THC cause to infants are seen during the teen. They become poor planners which make it rather difficult to keep the pace with their other fellows.

The use of marijuana in pregnant women is a cause for concern everywhere and it is advisable that women should stay away from using marijuana not only for their health but also for the life of their offspring. The effects of marijuana that they absorb in their blood during infancy end up affecting them during their entire lives. THC is a dangerous compound and so women should avoid interacting with it to save their children from long-term neurobehavioral anomalies.

Dr. Dalal Akoury (MD) is an experienced doctor that has helped many cancer patients in their fight against the disease. She is also dedicated to offer help to addiction patients. She founded AWAREmed Health and Wellness Resource Center which is home to many people seeking health breakthrough. Call on her now and learn more on how to fight drug addiction.

Long Term of THC on Neurodevelopment of Fetuses

Methamphetamine and Pregnant Women

September 16, 2014

Methamphetamine Causes Health Problems to Pregnant Women

Methamphetamine is drug with many names, users have given it very many names but this is not strange as this is always the case with any illegal drug. This drug is illegal and users call it crank, ice, speed, crystal and meth just among the many tittles it has got just in a bid to conceal what it really is from concerned authorities. This drug is used as a stimulant. It works in such a way that it floods the brain with extra dopamine hence stimulating the entire central nervous system (CNS). Dopamine is a chemical that is known to stimulate pleasure and this has led to use of not only meth but also other illegal drugs that induce production of dopamine.

methamphetamine

The use of this drug is not good especially to the women who are on their way to being mothers. Pregnant women should avoid the use of this drug more than anybody else. This is because it affects pregnancy negatively in many ways and if a woman continues to indulge in the risky behavior of using this drug when pregnant then at least she should know the dangers she is exposing herself to.

Generally, Methamphetamine causes irregular heartbeat, insomnia, paranoia, anxiety, heart damage, stomach cramps and high blood pressure just among the many side effects it’s known to cause. These side effects are not good for a pregnant woman and affects them adversely here are some more was that this drug adversely affects the life of a pregnant mother.

Methamphetamine may cause Placenta Abruption

Placenta abruption is the case when the placenta prematurely gets detached from the uterine wall. When placenta gets detached from the uterine wall before labor has begun it is termed premature and it can cause even death of both the mother and the child if emergency medical attention is not sought. Normally, the placenta remains attached to the uterine wall until after delivery after which it gets detached in thirty minutes. If accidental abruption occurs, emergency cesarean procedure must be done without which the mother and the baby may be lost to death. Methamphetamine affects the placenta adversely as it constricts the blood vessels hence causing lack of oxygen and nutrients to the baby. This leads to long term effects on the baby as a result of lack of significant nutrients in early life. Placenta abruption is dangerous and therefore it is worth quitting the use of methamphetamine for.

Meth and Preterm labor

Naturally the body of a woman should be able to know the right time to give birth but women who are victims of drug addictions have their bodies disabled to sense this right time. This may lead to early labor. Scientists have not made it known what causes the contractions during the 9 month gestation periods but several research findings have found that women who continue to use meth during their pregnancy mostly fail to contain the pregnancy to the full nine months. In United States alone half of women who use this drug during their pregnancy fail to carry the pregnancy to full term. Most of women using this drug give birth to underweight babies if they are lucky enough to carry the pregnancy to the full term.

Methamphetamine causes high blood pressure

As scientists have proved, Methamphetamine increases catecholamine activity in the branch of the peripheral nervous system responsible for controlling heart rate and blood pressure. This is the basis of all the heart related problems caused by this drug; Excessive catecholamine activity. The high levels of catecholamine are cardio toxic hence causing constriction and spasm of the blood vessels, rapid heart rate (tachycardia), high blood pressure (hypertension), and rupture of heart muscles. It may also lead to increment in the sizes of heart muscle tissues which in turn narrows the heart muscles. In the end of it narrow vessels leads to high pressure building in the blood vessels. Possible death of the heart muscle.

methamphetamine

In pregnant mothers high blood pressure can cause serious complications, the foetus is still having most of its features being developed and its blood vessels are still very weak to put up with high blood pressure.

Methamphetamine and Growth retardation

A child who is born of a mother who is addicted to meth and continued to use it during the gestation period is exposed to myriad of health problems. To begin with it is known that the drug constricts the vessels through which oxygen and nutrients are transferred from the mother to the baby, this causes deficit in the nutrients that reaches the baby and this explains why most women who continued to use this drug end up giving birth to babies that are underweight. These nutrients that the baby has missed are very crucial for its growth and this is just one way through which the use of methamphetamine causes growth retardation in babies born of mothers addicted to this drug.

Generally, a pregnant woman should avoid the use of methamphetamine at all costs as it causes serious health problems to both of the baby and the mother. Among other problems that it can cause is stillbirth. This is when a baby dies in the uterus after being alive for the 24 weeks. No woman would be happy to have a stillborn baby and so all pregnant mothers should avoid methamphetamine.

Dr. Dalal Akoury (MD) is an experienced doctor that has helped many cancer patients in their fight against the disease. She is also dedicated to offer help to addiction patients. She founded AWAREmed Health and Wellness Resource Center which is home to many people seeking health breakthrough. Call on her now and learn more on how to fight drug addiction.

Methamphetamine Causes Health Problems to Pregnant Women

Drugs Can Behave Like Neurotransmitters

September 15, 2014

Drugs Can Mimic Neurotransmitters

Drugs will automatically interfere with the bodily functions. That is guaranteed. But some drugs do not only alter minor body functions but go a step further in inhibiting the functions of neurotransmitters. Most of the drugs that can mimic or interfere with the functions of the neurotransmitters in any way are mostly hard and are hence illegal in many parts of the world. The brain is the engine that drives all the body functions. Even as you are reading this article you do not see with your eyes but you see with your brain. It has various mechanisms through which it accomplishes all the functions of the body. Before we learn how the drugs can affect the neuron transmitters it is good to know how they work.

Neurotransmitters are very crucial in the system. They are the chemicals that transmit messages from one nerve cell to another. Nerve cells are known as neurons. The nerve impulse travels from the first nerve cell through the axon, a single smooth body arising from the nerve cell to the axon terminal and the synaptic knobs. Each synaptic knob communicates with a dendrite or cell body of another neuron, and the synaptic knobs contain neurovesicles that store and release neurotransmitters. The synapse lies between the synaptic knob and the next cell. For the impulse to continue traveling across the synapse to reach the next cell, the synaptic knobs release the neurotransmitter into that space, and the next nerve cell is stimulated to pick up the impulse and continue it. An interference with the neurotransmitters can adversely affect the flow of message within the nervous system.

A point to note is that there is neurotransmitter compatibility, that is every transmitter is designed to be bound by a specific receptor. Some drugs are structurally similar to neurotransmitters and hence may be bound by the receptors and hence mimic the functions of the neurotransmitters. The drug will therefore disrupt the functions of the neurotransmitters adversely affecting the whole neuron system. Typically, this is like having an intruder into your personal computer- he will definitely interfere with your programs.

Here are some of the ways through which a drug can interfere with the neurotransmitters functions.

Stop the chemical reactions that create neurotransmitters.
Empty neurotransmitters from the vesicles where they’re normally stored and protected from breakdown by enzymes.
Block neurotransmitters from entering or leaving vesicles.
Bind to receptors in place of neurotransmitters.
Prevent neurotransmitters from returning to their sending neuron (the reuptake system).
Interfere with second messengers, the chemical and electrical changes that take place in a receiving neuron.

Marijuana for example has a compound known as THC which is known to mimic the functions of various neurotransmitters. It mimics the activities of a natural neurotransmitter called anandamide. Anandamide is an important neurotransmitter as it is charged with the role of boosting memory and learning, reducing pain, and stimulating the appetite. Anandamide normally works in conjunction with dopamine, and together these neurotransmitters turn on and turn off different chemical pathways as required so as to accomplish certain functions.

The fact THC mimics the Anandamide does not mean that it will work as that natural neural transmitter would. When a person takes marijuana THC binds to cannabinoid CB1 and CB2 receptors, which are located in several parts of the brain namely, the hippocampus, cerebral cortex, cerebellum, and basal ganglia. These brain areas are responsible for short-term memory, coordination, learning, problem solving, and unconscious muscle movements. When THC gets itself bound in the cannabinoid receptors, it blocks natural neurotransmitters like anandamide that need to bind to those sites to achieve all their functions. This therefore makes the functions of these neurotransmitters unaccomplished. When THC prevents anadamide from doing its job, the delicate balance between anadamide and dopamine is thrown off and suddenly a person will feel euphoric, off-balance, hyperactive, senseless to pain and unable to retain information.

Nucleus accumbens Reward Mechanism (addiction)

neurotransmitter The core structures of the brain reward pathway are located in the limbic system. These are a set of primitive structures in the human brain. Typically, the function of the limbic system is to monitor internal homeostasis, mediate memory, mediate learning, and experience emotion. It also enables important aspects of sexual behavior, motivation, and feeding behaviors. The primary parts of the limbic system include the hypothalamus, amygdala, hippocampus, septal nuclei, and anterior cingulate gyrus. Also important in the function of the limbic system is the limbic striatum, which includes the nucleus accumbens, ventral caudate nucleus and the putamen. The nucleus accumbens, often abbreviated as (NA) has been implicated as an especially important structure of the brain reward pathway because it is targeted by drugs of abuse.

When the brain becomes exposed to a certain drug, it begins relying on self stimulation as opposed to the natural neurotransmitter induced stimulation and this is what causes addiction. Several experiments have been done on animal models by use of electrodes that are placed into the nucleus accumbens under conditions of imposed environmental stress. Through these experiments the dependence on drugs for stimulation in brains exposed to these drugs is seen.

Dr. Dalal Akoury (MD) is an experienced doctor that has helped many cancer patients in their fight against the disease. She is also dedicated to offer help to addiction patients. She founded AWAREmed Health and Wellness Resource Center which is home to many people seeking health breakthrough. Call on her now and learn more on how to fight drug addiction.

Drugs Can Mimic Neurotransmitters

The Breast Size and Shape

September 11, 2014

The Breast Size and Shape – Does Weight Training Reduce Breast Size In Women?

The Breast Size and Shape. There is hope of restoration through weight exercise.

Listening to ladies share among themselves about their desire to keep the good looking shape they desire you will probably came across one of the most common myths about weight training for women. The common myth is that “weight training reduces breast size and creates a flat manly looking chest”. This is a misconception which has prohibited many women from integrating weight training into their quests to lose weight to shape up their bodies. An exercise that unavoidably leads to failure since weight training is without actually the most effective way to really tone up and develop a tight body. What about the prospect of becoming flat chested? To answer that I can honestly say that unless you plan on starving yourself or using anabolic steroids, women have little to worry about in terms of their breasts getting smaller from weight training. In fact most tend to see a slight increase over time!

When weight training is properly executed with sufficient intensity, adequate rest and nutrition will bring about an increase in muscle size of any part of the body that is being worked. This holds true whether it be it the pectoralis muscles of the chest (or pecs as many call them) or the muscles of your arms and legs. The way that this process (hypertrophy) works is that individual muscle fibers will get bigger (slightly bigger, that is, you won’t see mountains of muscle sprout on a woman without the use of anabolic steroids as it takes men with ten times more testosterone, several years to develop a muscular physique) or they will split and then get slightly bigger. The fibers of your pectoral muscles are all constituents of skeletal muscle whereas breast tissue is made up of sex specific adipose tissue (fat), ligaments, connective tissue and mammary glands. There are no skeletal muscle fibers found in the breasts as they simply sit directly over the pectoralis muscles. Weight training therefore can have no direct effect on them at all.

Weight Training only affects the muscles underneath and not the Breast

Thus breast tissue cannot be subject to hypertrophy or get larger due to weight training, but by increasing the size (slightly, ladies) of the pectoral muscles under the breasts there will be a natural increase in overall chest size. It may then appear that the breasts look a bit larger as they will stand up a bit more, which, is something most women would not mind. However the actual size and composition of the breasts themselves will not change. According to a study conducted in the University of Arizona back in 1985 ascertain this phenomenon in a 21 day study that used concentric and eccentric contractions with a specialized chest exercise machine. After the three week program researchers found no changes whatsoever in the size, shape or volume of the breasts of the women participating after extensive scientific measurement.

So what about those flat chested women in the magazines with thickly developed chest muscles and no breasts? The ones that are so often parodied and ridiculed? Firstly it should be noted that the female bodybuilders that we typically see in magazines or on the internet use extensive amounts of drugs to attain a degree of muscular development and body fat reduction and that is not in any way possible without pharmaceutical intervention.

These athletes do not in any way represent what a regular woman would look like if they trained with weights, no matter how long or how hard they trained. The size and shape of breasts in a healthy woman is fairly resistant to change as long as there are normal conditions of hydration and food availability. That being said, in cases of extreme under nutrition or calorie restriction as is often the case for athletes trying to get lean or individuals with eating disorders like bulimia or anorexia where there is a significant reduction of body-weight and body fat, the breasts, which have a high proportion of fat, will shrink. In the case of female bodybuilders- you see the dense muscle tissue in their chest area and no breasts and the assumption is erroneously made that somehow the weight training made their breasts go away. Weight training has nothing to do with it, as shrinkage comes from the reduction in body fat and nothing else.

Weight training can help you look better

Even with all these, natural athletes who don’t aspire to have 3% body fat levels don’t tend to have the same flat chested look as their drug using counterparts, nor the thickly muscled pecs that many find a bit off putting. Due to the reduced body fat of the average elite athlete there is some reduction in breast sized as compared to the general population, as they diet down, but most of the size lost in their chest area comes back when they eat normally and reduce their levels of fat burning activity.

The other factor that can cause breast size to change is obesity in which case the breasts become larger as body fat increases past healthy levels. Some women who are overweight see this increase in breast size as a positive attribute and are reluctant to exercise or diet for fear of reducing their bust size. For someone who is overweight to trim down to a lean and toned body, there will always be some loss of breast size- from the loss of body fat. But keep in mind that weight training can help lift what remains and make you look better in all dimensions.

Finally irrespective of what is running across your mind it is very important that you’re in constant consultation with weight lose specialist for a better outcome all through. This is a service you will get under the able leadership of doctor Dalal Akoury who is also the founder of AWAREmed Health and Wellness Resource Center. Calling doctor Akoury today will be the starting point of attaining your general physical well-being because at this facility doctor Akoury and her team of experts will only focus on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE and your life will be fully transformed for a very long time.

The Breast Size and Shape – Does Weight Training Reduce Breast Size In Women?

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