Category Archives: Heavy Metal Toxicit

Curcumin and triple negative cancer

August 7, 2014

   Curcumin Is a Triple Negative Cancer Treatment Compound

curcuminCancer doctors and researchers have always done a great job in trying to find us the best treatment to this disease. This is not because there are no cancer treatments that work but because some of the most common conventional cancer treatments like chemotherapy radiation therapy and surgery have left some loophole that needs to be filled for cancer treatment to be effective and safe for all cancer patients. Chemotherapy and radiation therapy have been used for a long time in cancer treatment. However they focus on killing of cancerous by poisoning them. When done the chemotherapy drugs not only kill the cancerous cells but also kill the healthy body cells that are vital for optimum body functioning . This leads to many side effects that make cancer treatments a very painful ordeal. Several cancer patients have died after chemotherapy because of the severe side effects that it is associated with.

Today we have very many alternative cancer treatments thanks to the tireless researchers and cancer doctors who have continued to do research on better cancer treatment alternatives. The researchers have availed varied cancer treatments alternatives ranging from dietary manipulations to natural cancer treatments. Use of natural cures of cancer treatments have since gained popularity due to their availability and cost effectiveness. Another reason that has seen cancer patients seeking natural cancer treatment alternatives is because of the facts that they are devoid of the life threatening side effects that most conventional cancer treatment methods are always associated with. Use of fruits and vegetables are popular today and are sought after as some of the most effective cancer treatment methods worldwide. Some of the diets that have been proposed to work best in cancer treatment involve the use of these fruits and vegetables. The Gerson’s therapy is one of the most famous alternative cancer treatments that have been used in cancer treatment. Researchers have also been able to discover compounds that are effective in fighting cancer in some of these fruits and vegetables. Recently researchers found that a compound in the peach fruit helped in fighting cancer. However peaches are not the only fruits that have been promoted as effective alternatives to cancer treatment. Berries among other fruits are part of the long list. One of these naturally occurring compounds that help in fighting cancer is curcumin. Curcumin is an effective component in turmeric.

Curcumin

Curcumin is a compound in Turmeric. Turmeric is a member of the ginger family, turmeric has been highly valued for its many medicinal abilities, among most of its medicinal abilities is that it is very effective in reducing inflammations. Turmeric is a common spice to Indians who value it for its health benefits. Curcumin is the most active component of turmeric.  Curcumin is effective in reducing inflammations. It exerts its anti-inflammatory activity by inhibiting the enzymes and prostaglandins that are essential for inflammation. Curcumin has not only been promoted as an anti-inflammation agent but several studies have proved that it helps in cancer treatment.

Not long ago researchers at Baylor University Medical Center in Dallas conducted a research that involved dividing 45 patients with rheumatoid arthritis into three groups. One group received curcumin, the second group was given a standard rheumatoid arthritis drug and the third group was given both. After eight weeks, both the group who took curcumin alone and the group that got both the drug and the spice had a greater reduction in symptoms such as joint swelling and pain compared with those who only took the drug devoid of curcumin. It was also noted that those who were on the curcumin did not suffer any side effect as was the case with those who were under the standard drugs. The findings of this research is pointer that curcumin can help in cancer treatment as inflammation is a feature in cancer.

A new research study done by researchers from Zheijian Provincial People’s Hospital in Zheijiang, China shows that a compound in turmeric known as curcumin, which gives the spice its characteristic saffron-like color, has the ability of inducing  cell death, also known as apoptosis within triple negative breast cancer cells.

Triple negative breast cancer (TNBC) is the most difficult cancer to treat as these cancer cells are very resistant to drugs. These cancer cells do not have the characteristic receptors for estrogen, progesterone and Her2/neu. This makes it very hard to treat a patient with Triple negative breast cancer (TNBC) as most treatments especially the conventional cancer treatments target these receptors that are missing in the cells. Without these receptors such treatments do not work. For example Tamoxifen targets estrogen receptors, in absence of estrogen receptors Tamoxifen cannot work in cancer treatment. For this reason, TNBC is considered the most aggressive, the most likely to be treated with less-targeted (and therefore more toxic) forms of chemotherapy, and the soonest to return when treatment fails. For Triple negative breast cancer (TNBC) target therapies are not the best options for treatment.

Today it is approximated that between 15-25% of all breast cancer cases are triple negative. This statistics remind us of other treatments that can best work in cancer treatment. Unfortunately those bodies that are known to create awareness on Triple negative breast cancer (TNBC) are only focused on raising money for a pharmaceutical cure that is yet to be made. Curcumin can effectively be used in treatment of Triple negative breast cancer (TNBC) as it works better here than any other target therapies.

CurcuminTriple negative breast cancer (TNBC) can be treated best in integrative cancer centers such as AWAREmed where all the possible cures will be put to use to ensure that the disease is fought and won.

Dr. Dalal Akoury (MD) is an experienced integrative cancer doctor that has helped many cancer patients in their fight against the disease. She has worked hard not only in treating the disease but also in availing informational support to cancer patients at Awaremed which has become a place called home for many cancer patients. Call on her now and get help on cancer.

   Curcumin Is a Triple Negative Cancer Treatment Compound

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Drug Addiction and Mental Illness

August 7, 2014

Drug Addiction and Mental Illness – Dual Diagnosis

Addiction

Drug Addiction and Mental Illness put together will bring your life to a halt. Seek for help and get your life back, it is possible all is not lost for you.

Dual means two and so when we talk of dual diagnosis we refer to a term used to denote people with mental illness and at the same time suffers from drug addiction and alcohol. The combination of the two is very complex and administering treatment to persons suffering from both mental illness and drug addiction is difficult and more complicated compared to when both were to be treated separately. It is very worrying that people suffering from mental illness are also struggling with drug addiction concurrently. The environmental factors greatly influence how people get infected with these two health conditions. For instance people with low socioeconomic status, military veterans and those with multiple general medical illness tends to bear more risk of abusing drugs, alcohol and other stimulants. Dual diagnosis is so common this day’s that statistics indicate that one-third of all alcohol abusers and more than one-half of all drug abusers are also battling mental illness.

Drug Addiction and Mental Illness – Relationship between substance use and mental illness

The relationship between mental illness and substance abuse or dependency is complex and is often considered in the following ways:

  • Drugs and alcohol may be used for self-medication. In such cases, people with mental illness may have untreated or inadequately treated conditions (such as anxiety or depression) that may “feel less painful” when the person is high on drugs or alcohol. Unfortunately, while drugs and alcohol may feel good in the moment, abuse of these substances doesn’t treat the underlying condition and almost without exception makes it worse.
  • Drugs and alcohol can deteriorate the underlying mental illnesses. This can happen both during acute intoxication (e.g., a person with depression becomes suicidal in the context of drinking alcohol) and during withdrawal from a substance (e.g. a person with panic attacks experiences worsening symptoms during heroin withdrawal).
  • Drugs and alcohol can cause a person without mental illness to experience the onset of symptoms for the first time. For example, a twenty-year old college student who begins to hear threatening voices inside of his head and becomes paranoid that his chemistry professor is poisoning his food after smoking marijuana could represent a reaction to the drug (potentially called a “substance-induced psychosis”) or the first episode of psychosis for this individual.

Drug addiction and alcohol always results in a worse prognosis for a person with mental illness. People who are actively using drugs are less likely to follow through with the treatment plans they created with their healthcare providers they are not likely to follow their medication regimens and may not be consistent in keeping their appointments. If this continues over time it may lead to more psychiatric hospitalizations and other adverse outcomes. Active users are also less likely to receive adequate medical care for similar reasons and are more likely to experience severe medical complications and premature death. Drug addicts with mental illness are also at increased risk of impulsive and potentially violent acts. Perhaps most concerning is that people who abuse drugs and alcohol are more likely to both attempt suicide and to die from their suicide attempts. Individuals with mental illness and active substance or alcohol abuse are less likely to achieve lasting sobriety. The consequences of their addiction may be lead to severe complications like having legal problems with the authorities.

Drug Addiction and Mental Illness – Treatments for individuals with dual diagnosis

As indicated above treatment for dual diagnosis is very complicated and it will be very important to first address any life threatening complications due to intoxication. For instance the following conditions may require immediate medical care in the confinement of a health facility:

  • Extreme cases of alcohol intoxication may necessitate prompt medical treatment and can result in death if not arrested in good time.
  • Use of amphetamines, crack, cocaine and other drugs can result in heart complications like arrhythmias, heart attacks, stroke and even death.
  • Use of benzodiazepines (e.g. diazepam, clonazepam), opiates (e.g., oxycodone, oxycontin) and other downers can result in extreme sedation and potentially death in overdose.

Drug and alcohol withdrawal can lead to medical emergencies requiring immediate treatment. This can occur when a person who has been regularly using a particular substance has become addicted to that substance (the body has become physically dependent on the substance) and abruptly stops using. The following may necessitate immediate medical care in the hospital setting:

  • Alcohol withdrawal can result in heart problems (e.g., arrhythmias), seizures or delirium tremens (an acute delirious state), all which can be potentially fatal.
  • Benzodiazepine withdrawal can result in tremors (shakes), seizures and potentially death.
  • Under normal circumstances opiate withdrawal is not considered to be life-threatening but it can be a very traumatic and painful experience.

It is important that those struggling with drug addiction and alcohol seek help through processes like inpatient detoxification either by admission to a hospital or a detoxification facility where appropriate medications can be done to avoid serious complications of acute drug and alcohol withdrawal. Scientific studies has established that psychiatric treatments very effective in individuals who are not actively abusing drugs and alcohol and therefore total healing from substance abuse must be achieved and once this is done the underlying mental illness may be more successful. It is important to note that mental illness treatment is more effective when the patient is sober though it can still be done along detoxification process. There are many working options for recovering addicts to help them keep on the course and to avoid relapse on drugs and alcohol like rehabilitation centers or supportive housing besides these you may choose to return home to your friends and family who can be helpful in supporting you to continue the efforts. This can be critically important as a significant majority of people will relapse into drug and alcohol abuse at some point in their lives, even if they are eventually able to achieve long-lasting sobriety. I will further recommend seeing an addiction expert from time to time for evaluation. Doctor Dalal Akoury who founded AWAREmed Health and Wellness Resource Center is an expert of more than two decades and has been helping people globally get well from their addiction problems in the most natural way. This is one experience am sure you do not want to miss and so when you visit this facility doctor Akoury together with her team of experts will focus on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE.

Drug Addiction and Mental Illness – Dual Diagnosis

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Matrix Metalloproteinase Inhibitors

August 6, 2014

Matrix Metalloproteinase Inhibitors Are Gaining Popularity In Cancer Treatment

Cancer cells just like the healthy normal body cells have specific process that have to be accomplished in order for them to survive. Cancer doctors have known this for a long time and most of the alternative cancer treatments that we have today are best on the understanding of certain survival mechanisms. There are certain cancer treatment alternatives that are geared towards making them more vulnerable to chemotherapy drugs and are hence used alongside the chemotherapy as well as other conventional cancer treatment medications like radiation therapy. There are other more effective cancer treatment alternatives that aim at interfering with the cancer cell metabolism mechanisms hence starve them by denying them the ATP energy that they need to accomplish some of their cellular functions like growth and division to give rise to new cancer cell. The use of alternative cancer treatment are gaining popularity not because the conventional cancer treatment medications do not work but to find better ways of treating cancer patients by targeting the cancer cells while safeguarding the healthy body cells. This is a loophole that has to be filled. In conventional medicine the treatment targets killing of the cancer cell but the healthy body cells are also affected by the chemotherapy drugs and they die as well leaving the patient with lots of side effects that are very life threatening. The cancer doctors and researchers are trying to treat cancer strategically so that the patient is not put through the pain of going for repeated chemotherapy. Due to these different alternatives to cancer treatments that work effectively in different cases to combat cancer, the new breed of cancer doctors; the integrative doctors have become a favorite for cancer patients. This is because they are very knowledgeable in oncology and puts in use all the alternative cancer treatments (naturopathic) and the conventional cancer treatment in a bid to achieve a whole person healing of the cancer patient.

One of the best ways of treating cancer is to use inhibitors. These inhibitors affect the normal functioning of the cancer cells and hence a slow their growth and survival rates. Some of these inhibitors are also strong enough to induce apoptosis of the cancer cells. Matrix metalloproteinase inhibitors are some of the inhibitors that help in strategic fighting of cancer.

Matrix metalloproteinases, often known as MMPs are a group of enzymes that are involved in a number of normal cellular processes, such as regulation of endometrial growth and menstruation, and abnormal processes, such as tumor growth, invasion, angiogenesis, and metastasis. Matrix metalloproteinases play a major role in angiogenesis. This is because they degrade the basement membrane and stromal tissue which is an important process for migration of endothelial cells needed to form new blood vessels. They also play an important role in the entry and exit of tumor cells into the blood vessels hence foster metastasis. Due to their critical contributions in angiogenesis and metastasis they can be strategically targeted in cancer treatment by utilizing Matrix metalloproteinases inhibitors that will main all their activities.

Matrix metalloproteinases can be produced in two ways; either the tumor cells produce them themselves or they tissues surrounding the cancer cell produce them. Because of their role in cancer etiology they are highly regulated especially through gene expression. They are secreted in inactive forms and must be cleaved to be active. Moreover they activities are also controlled by the Matrix metalloproteinases inhibitors that surround the tumor cell.

Researchers have done lots of work in trying to investigate if the matrix metalloproteinase inhibitors can be used to maim the functions of the Matrix metalloproteinases and help in cancer treatment. Their research are based on the logic that Matrix metalloproteinases are crucial enzymes for tumor invasion and metastasis and is targeted the spread of cancer can be curbed. This treatment however does address the formation of primary tumors but again it can work in controlling the spread of tumor hence important.

Doxycycline as a Matrix metalloproteinases inhibitor

Doxycycline is a semisynthetic, chemically modified tetracycline compound that is rapidly absorbed and exerts biological effects courtesy of its antimicrobial activity. It has been used in the past in wound treatment and is also one of the most effective Matrix metalloproteinases inhibitor.

Clinical as well as lab tests have been one to show the effectiveness of Doxycycline in inhibiting Matrix metalloproteinases activities. As all these activities were done with a view of finding a possibility of using it in curbing metastasis. The study pointed out that an enzyme; MMP-2 is needed for the cancer cells to dig in or other to penetrate the normal tissues. Doxycycline has an inhibitory effect on the MMP-2 expression. This was verified by a lab test on smooth muscle cells and human aortic aneurysm tissue explants. The test revealed that Doxycycline inhibited the activities of MMP-2 on these tissues. However for effectiveness the concentration of the Doxycycline matters in its activity against the MMP-2. In the normal serum concentration just 5ml of Doxycycline affects the production of MMP-2 greatly.

By use of Matrix metalloproteinases inhibitors like Doxycycline, the cancer treatment becomes more effective and strategic as the cancer cells become targeted. With controlled metastasis and growth of cancer cells the patient can have a longer life and possibly the disease will be managed done with completely by an integrative cancer doctor who will combine other therapies to make the treatment more effective.

Dr. Dalal Akoury is an experienced integrative cancer doctor who has seen very many cancer patients journey to victory in their fight against cancer. She is available for consultations. Just call her now and begin your journey to victory against cancer.

Matrix Metalloproteinase Inhibitors Are Gaining Popularity In Cancer Treatment

 

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Obstacles of quitting Smoking

August 6, 2014

Obstacles of quitting Smoking – Things Not to do when helping a smoker to quit

Smoking

there are so many obstacles for quitting smoking. it should be our collective responsibility to put this problem to manageable levels.

I believe that you are not hearing for the fast time the dangers of smoking cigarettes or any other drug. The human body has no association with smoke emanating from cigarettes and in fact it is not just the smokers who are at risk of contracting smoking related health condition but research has established that even the secondary smokers find themselves with all the smoking related health complication just in the same way as full addicts. How then do we help our people who have subjected their lives in to drug addiction and in this case we are looking into smocking.

Obstacles of quitting Smoking – Helping smokers quit

It may not concern you that your friend is smoking and you’re not, you may hate to be near smokers because of the strong smell emanating from them due to the substances they smoke. This attitude may be justified due to secondary infections however this is not the best way to go about it. This should be a concern of everyone you and I included. We must do all we can to encourage smokers to stop and quit this habit completely.

The benefits of having a smoking free society is healthy for everyone and we must be persuaded to collective and individually do what we can. Therefore for you to be of help to your smoking loved one or any other person quit their habit, it is very important that you get to know what applications will work and those that may not work. This piece of information is very necessary as it will help you face the smoking obstacles when you finally begin the journey of being an instrument of bringing change in our smoking society and so if you have tried all you can to influence your target from smoking or this will has just crossed your mind and you are considering giving it a try, you must ensure that you take all the precautionary measures so that you do not end up falling prey to the effects of smoking as a result of secondary smoking. Your target is to win the mind of your friend into seeing the benefits of quitting smoking. Smoking causes serious damage to almost every single organ in the human body, so it can’t be good not now or ever. It may interest you to know that much as you may hate smoking those whom you’re trying to encourage to quit smoking may not share the same opinion with you and they may be doing the exact opposite which is loving what they do (smoking).

Obstacles of quitting Smoking – Hazardous Nicotine

Nicotine and all the associated habits that come along with smoking like holding, inhaling and reaching for cigarettes throughout the day are physically and emotionally addictive to smokers. Research has established that smoking is a killer the world over. Many people are losing their lives because of smoking and the statistics is worrying. In US for example about 393,000 lives are lost annually from smoking related illness. This is therefore a motivation for you and I to ensure that this figures come down by changing our attitude towards those who smoke, we must desire to love them and not hate them even if we hate their actions. It cost you nothing trying to bring help a smoker quit their habits and so if you haven’t been able to get that smoker in your life to quit, it’s important to keep trying again and again, even if you become a bother to them persist on you may become bad in their site but don’t let this discourage you because there is great benefit when you finally win and they quit entirely.

Obstacles of quitting Smoking – What not to do in helping a smoker quit

Love is a very powerful element is unlocking this smoking problem. It’s said that love and kindness is the language that the blind can see and the deaf can hear. Loving someone who’s tried repeatedly to quit but failed each time they try is very important. These people need to be cared for and letting them know that someone is there for them despite their struggle with smoking will encourage them not to give up. Words of encouragements are very necessary and you must avoid negative remarks like “I give up! You’re never going to quit!” these are very weighty statements and can impact negatively to the smoker they may wonder whether quitting smoking is possible or worth the effort they are putting. Nonetheless words of encouragement like “I’m not giving up on you and will be with you on this journey to the end of it” are useful statements which will remain in their minds for a long time and positively influences your loved one’s decision to stay the course.

Giving up on methods that aren’t working is a good idea, though. With smoking, it may be the “same approach, different day” or even “different day, different approach,” because it’s hard to know when something just might click and connect with a smoker’s desire to quit. It is therefore important that you keep trying and showing concern while you figure out what definitely isn’t working or what’s driving them to smoke more. Doing this on your own may be overwhelming at times and so you may need the guidance of a professional from time to time. At AWAREmed Health and Wellness Resource Center you will meet addiction professionals who will help you in your effort of quitting smoking in the most natural way. This facility was founded by Doctor Dalal Akoury who has been in this line of treatment for over the last two decades making her to be very experience to handle your smoking problems in a much more dignified way. While at this facility, doctor Akoury together with her team of experts will work round the clock to ensure that your smoking problem is no more. They will attend to you in many ways among them will be by focusing on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE  and your life will never be the same again.

Obstacles of quitting Smoking – Things Not to do when helping a smoker to quit

 

 

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Genetic Predisposition

August 5, 2014

 

Genetic and Viral Predisposition To Cancer Is A Crucial Subject In Cancer Treatment

Cancer has caused serious threat to the world’s population and has still continued to affect the people of all continents. It is among the leading causes of death in the world today. Despite the many alternative cancer treatments, the disease is not yet conquered as it is still causing pain to us every day after grabbing our loved ones away from us. According to a world health report of 2002, close 7.1 million deaths are caused by cancer each and every year. With the most prevalent of these cancers being lung, stomach, colon, liver, breast and esophagus cancer, in that order of occurrence. Conclusively, these cancers are responsible for over 4.2 million deaths. Additionally, another World Cancer Report of 2003 (IARC 2003) predicts that deaths caused by cancer will increase by 50% in the next 20 years. In the past cancer was thought of as diseases of the developed countries but as years passed by even the third world countries became infested with this disease. The cases of cancer in the third world countries are attributed to the demographic changes as well as changes in lifestyle. The way of life has changed even in these third world countries and this may even increase the percentages of cancer infection.

Cancer is a disease that has many causes and of the many cause are very complex gene interactions. A person may not be born with cancer but he may have higher chances of getting cancer. This is what is known as genetic predisposition. Genetic predisposition maybe caused by a presence of one or more gene mutations and this may happen even if the allele’s combination is normal.

Genetic predispositisions is a subject that has made researchers as well as health organizations like World Health Organization to do lot of research work to find out how far genetic predisposition can lead to the disease. Apparently the researches done were not only done in relation to cancer but other non-communicable diseases like diabetes, cardiovascular disease, asthma, and some mental illnesses.

In cancer, a person may be born with genes whose compositions were altered by lifestyle habits or exposure to harmful chemicals that goes along way in changing the DNA composition of the body cells. The body has tumor suppressors that help it in fighting and preventing tumors but when these tumor suppressors become weak which may be caused by exposure to harmful chemicals then a person becomes more vulnerable to cancer infection. Carcinomas are the most probable result of failure of the tumor suppressors.

It is important to understand how genetic predisposition affects a person. Cancer is not a disease that should be toyed with and so it calls for early examination to show whether a person has genetic predispositions that can play a role in making them to have cancer. Doctors advice that by knowing if a person has these genetic predispositions, it can help them to adopt lifestyles that will help them evade the formation of cancer cells in them. It is good to note that not all people who are born with genetic predispositions to cancer eventually get the disease; the choice of lifestyle will either make him evade the disease or will even hasten the formation of the cancerous cells in them. Those who are born with genetic predispositions to cancer can avoid the disease by avoiding such behaviors that may increase their risk to cancer such as smoking tobacco, drinking alcohol and engaging in sexual activities with many sexual partners. There are lifestyle modifications that will help a person who is born with genetic predispositions to cancer live longer without being affected by the disease. These may involve healthy eating and detoxifying the body naturally by eating those vegetables and fruits that are rich in antioxidants. It is also advisable for such a person to seek help from an integrative cancer centre where the doctors may offer guidance on how to live a life that is cancer free despite the genetic predisposition to cancer he was born with.

Promotes cancer cell formation

As known, cancer cell forms when there is mutation in the genes that play a major role in cell multiplication and repair. When these mutated genes are passed over to an offspring, the offspring becomes highly vulnerable to cancer. However the process through which these genes may turn cancerous may take time probably beyond 20 years. The mutation of vital genes such as suppressor genes, oncogenesis and genes involved in DNA repair leads to genetic instability and to progressive loss of differentiation. Tumors grow because cancer cells lack the ability to balance cell division by cell death and by angiogenesis. The transformed cells lose their ability to interact with each other and exhibit uncontrolled cell growth. They will eventually invade the tissues that surround them and spread into the blood stream after which they can reach very organ in the body.

GeneticGenetic predisposition to cancer undeniably has a role in cancer formation. One of the mostly inherited mutations of BRCA 1 gene is known to cause breast cancer in women. Those who have this gene mutation have higher chances of getting a breast cancer as well as ovarian cancer. Earlier identification of the germline mutations can be achieved through genetic testing. This will allow the person to adopt cancer preventive measures by seeking help from integrative cancer centers that will give natural means of suppressing the mutated gene expression.

Dr. Dalal Akoury is an experienced integrative cancer doctor who has seen very many cancer patients journey to victory in their fight against cancer. She is available for consultations. Just call her now and begin your journey to victory against cancer.

Genetic and Viral Predisposition To Cancer Is A Crucial Subject In Cancer Treatment

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