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stem cells

Stimulant induced skin picking

Stimulant induced skin picking

Stimulant induced skin picking can be controlled effectively at AWAREmed Health and Wellness Resource Center

Stimulant induced skin picking: Cocaine abuse

Stimulant induced skin picking due to excessive and abuse of crack cocaine has become more common as more people use crack disorderly. This has necessitated the sudden increase in negative health issues linked to this habit. Professionally in the medical understanding stimulant induced skin picking is seen as a compulsive foraging response (CICF – ‘cocaine induced compulsive foraging’) but the compulsion to skin pick has also been called psychogenic excoriation, delusional parasitosis, self-inflicted dermatoses, dermatillomania, formication, or hypoesthesia; which is quite surprising considering that there has been so little research on the subject.

Stimulant induced skin picking: Characteristics of skin picking

The features of skin picking may include excessive scratching, picking, gouging, lancing, digging and squeezing of normal or slightly marred skin. Even though the whole body can be involved, commonly the most picked areas include; fingernails, face, lips, scalp, arms and legs. This is made possible because drugs like cocaine, methylephenidate, phenelzine amphetamine and anticholinergic drugs often produce increased nerve activity tactile sensations like burning, tingling and crawling (worms under the skin) that can lead to skin picking. So while it is clearly a chemical reaction to the drugs you’re taking, it can be closely linked with psychological issues such as extreme anxiety or childhood trauma.

Stimulant induced skin picking: So why do some people skin pick excessively, where others don’t?

Studies suggest that it’s a coping mechanism for dealing with emotional pain. Physical pain distracts the individual and can help to alleviate feelings of guilt through self-punishment. Many S-P’s (skin pickers) report increased levels of tension prior to skin picking and a sense of relief or satisfaction following the picking. Some experience an altered state of consciousness whilst picking resembling a dissocialized state. However, lack of pain during picking episodes may also be related to opioid dysregulation. We can see elevated levels of B-endorphin in S-Ps, because pain, in this case through self-injurious behavior, leads to the release of B-endorphins, which in turn leads to the release of tension.

Stimulant induced skin picking: Crack cocaine

Doctor Dalal Akoury who is also the founder of AWAREmed Health and Wellness Resource Center registers that cocaine increases the activity of dopamine, a neurotransmitter in the automatic nervous system associated with pleasure which is important for reinforcement of behavior. However, for reasons we don’t have the space to go into, too much use of cocaine can lead to a lack of dopamine in your system, which in turn leads to mood and anxiety disorders. S-Ps often suffers from one or more of the following conditions:

  • Agoraphobia
  • Bipolar disorder (manic depression)
  • Body dysmorphic disorder (hated self-image).
  • Dysthymia (depression tendencies)
  • Eating disorders
  • Kleptomania (compulsive stealing of objects) and
  • Major depression
  • Obsessive compulsive disorder
  • Panic attacks
  • Post-traumatic stress
  • Trichotillomania (hair /eyelash/body hair pulling)

Beside the mention conditions, some studies have also established that more than half of the individuals with serious skin picking conditions also reported a history of body rocking, thumb sucking, knuckle cracking, cheek chewing and head banging. Along-side with all these, skin picking also causes a lot of anguish. Like for instance, the victim can feel embarrassed and this may lead to shame and even impaired social functioning and in some cases people withdraw altogether from social activities and confine themselves to their home. Some people also experience medical complications as a result of skin picking, like ulcers, infections, permanent discoloration and scarring. Remember that too much scratching leads to open wounds and sores and when this is combined with injecting, infection can travel from the skin to the blood, causing serious illnesses such as septicemia or endocarditis. And that should be an incentive for you to schedule for an appointment with doctor Akoury for a more professional medical approach.

Stimulant induced skin picking: Cocaine abuse

 

 

 

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stem cells

Stem cell for regrowing cartilage

Approximately 20 to 40 million Americans suffer Osteoarthritis which is also one of the most popular forms of arthritis. This complication involves an early-stage deterioration of articular cartilage. Cartilage is simply a connective tissue without nerves or blood vessels.

One of the symptoms is the pain that results from inflammation caused by the production of destructive enzymes and can also be influenced by biomechanics.

In the previous year’s treatment of osteoarthritis used to be symptomatic that involved injections of glucocorticoids in the joints, oral ingestion of inflammatory drugs or injection of visco-supplements that acted as intra-articular lubricants. Unfortunately, these methods were not as safe as they were claimed to be. They were linked to several potential side effects and the worst; they weren’t as effective as they were assumed to be.

In the year 1990’s scientists developed an interest of creating osteoarthritis drugs. Unfortunately, their efforts weren’t successful.

Stem cells for regrowing cartilage have become a center of interest. However, there are a few issues that need to be addressed. Many people still question which kind of stem cells are to be used and those that shouldn’t. There are also a few questions about how stem cells would work for regrowing cartilage, potential risks, how their productivity can be enhanced and more.

 

stem cells

Recently, there was a breakthrough in the area of human pluripotent stem cells. It was originally established in the year 2007 by Shinya Yamanaka; Yamanaka was able to obtain adult stem cells. He then reprogramed them to work as cord blood stem cells. The results were stem cells that could differentiate to form any cells in the human body. However, the procedure has been accompanied by several issues.

Currently, a scientist can obtain mesenchymal stem cells that are found in the bone marrow. These stem cells work just like any other stem cell if placed in a correct environment together with growth activators.

Mesenchymal stem cells can perform a variety of functions, but can be limited to several organs. The good news is, it works for cartilage. However, it isn’t easy judging whether the procedure is as effective as it is assumed simply because their findings aren’t clear. It has also been realized that using MSCs in areas that have no cartilage may result in some complications.

It is, however, evident that the effectiveness of this procedure is short term and safe considering several factors such as improvements of cartilage. There are also no reported risks of cancer which has been one of the issues revolving around the use of pluripotential stem cells.

Conclusion

Currently, we can say that MSCs is the best approach that is obtained from the bone marrow plus many growth factors derived from plasma that is rich in platelet. For a successful harvesting to take place, use of ultrasound guidance by a professional is highly advised.

 

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embryonic stem cells

Reasons you need to start storing and growing your embryonic stem cells

There are some reasons scientists are pushing for embryonic stem cells use which leads to the question, what is so special about these stem cells? What makes them better than others?

Embryonic stem cells are quite similar to adult stem cells. What makes them different is that fact that they are still young and can differentiate to form all kinds of body cells. This characteristic enables them to be used to treat a variety of illnesses that include, spinal cord injury, heart failure, diabetes or Alzheimer’s disease.

Scientist thinks that this is possible simply because they can change to any cell in the human body. In certain cases, physicians grow cells in the laboratory that will be used to replace the cells that are either damaged due to an injury or just old to perform their roles.

However, there is still a lot of research being done to find out if this therapy can be used to cure illnesses. Due to this, there is are clinical trials taking place in the US and other countries. In addition to their ability to treat several complications it has also been proven that human embryonic stem cells can be used to recover from surgery, heal burns wound and more.

If you are an in vitro fertilization patient, there are high chances you may have more than one embryo you are planning to use in pregnancy. If you find out that they are of an inferior quality, you might no longer want to use them.

 

embryonic stem cells

When this happens, you might want to grow your discard frozen embryos to form human embryonic stem cells. Just like physicians do when banking cord blood samples, these embryonic stem cells can be kept for future use. Science has proven that, provided the human embryonic stem cells are kept in a -320 degrees Fahrenheit liquid nitrogen, they’ll be able to last a lifetime.

Why do you need to store your embryonic stem cells?

Your cord blood stem cells created will be genetically identical to you are anyone related to you by 50%. The fact that they are created or obtained from a young embryo, it is often assumed that their immune identity isn’t fully functional.

This might be preserved to a point where the cord blood cells can be grown to form specific cells in the body. As a result, the body of a person who is related to you won’t be able to reject simply because they won’t be able to identify it as an outside object.

The bottom line

Having your cord blood stem cells stored may come in handy in future. One of your family members might need an organ replacement, tissue repair and much more, but finding a donor that matches him or her might not be easy, and this is where your human embryonic stem cells might find their use.

 

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adult stem cell

The future of stem cell therapy

Of all the cells in human body, stem cells are the most essential. Unlike other cells, they have the ability to differentiate to form several kinds of cells with varying functions. They can also self-generate to produce extra stem cells.

While still young, they are capable of becoming any cell in human body. They have the ability to copy and adopt the makeup of a particular cell, a trait that enables them to repair the human body. This is also one of the characteristics that make them quite effective in treating several diseases through a process called cell therapy.

Adult stem cell transplantation is a common type of stem cell therapy that is being used to treat several blood complications as well as cancers such as leukemia, lymphoma and more.

 

adult stem cell

To use a bone marrow, physicians target a bone marrow of a donor whose blood matches that of the patient. The bone marrow is obtained through a process of chemotherapy or radiation. The bone marrow is then transferred to the body of the patient. In the patient’s body, the cells start top self-generate creating new cells to replace the old or damaged cells. It is then followed by a similar process, but this time, the stem cells aren’t obtained from the bone marrow.

Another useful source is the umbilical cord. It is indifferent from the first two mentioned above. The only difference is that the stem cells are derived from the umbilical cord blood of a newborn baby. They are also considered the best simply because, it isn’t easy for any patient’s body to reject the cord blood cells unlike what is evident with other sources such as the adult stem cells and more.

This is because these kinds of cells are still young and have some features that no human body might recognize as an external substance. This is also one of the reasons several unending debates surround this kind of therapy.

A lot of people think that destroying an embryo to get this kind of cells is going against ethics. A scientist has tried to disapprove this misconception by saying that these kinds of cells can be obtained from an embryo that is no longer in use. Instead of disposing of an embryo when they no longer need it, mothers donate these embryos to labs where they are used as a source of stem cells.

Cord blood cells have provided lots of opportunities for an extended research on stem cell therapy. Researchers have developed a theory that this kind of cells, unlike the adult stem cells, have the ability to treat several diseases such as neurological as well as cardiac disorders. As a result, informed parents have started preserving the blood of their newborn babies for future emergencies.

 

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stem cell research

Will the State be able to fund stem cell research in future?

Stem cells can be defined as undifferentiated cells that are capable of turning into particular types of cells in the body. Up to now, it is apparent that it is one of the best remedies for several complications that include, heart attack, spinal cord injury, diabetes, stroke, Alzheimer’s and Parkinson’s illnesses.

Since its discovery, there has been a lot of debates of whether some types of stem cells could work or not. Among the most controversial forms is the stem cells that are obtained from the human embryo. There are a few groups who don’t agree with the way the embryonic stem cells are obtained simply because it involves the destruction of the human embryo.

In the year 2001, President Bush made it clear that he was going to allow stem cell research to be funded federally after confirmation of death. He further stated that no federal funds would be availed for new stem cell lines. There have been several issues on the matter. A review on the matter was aired two times on a 60-minute television show on 12th and 26th February in the year 2006.

 

stem cell research

In New Jersey, the Democrats fully accept stem cell funding while some Republicans oppose it. The New Jersey has suggested spending up to $150 million on research that has fewer controversies such as stem cells from placentas, cord blood, and other tissues. It also proposed to spend $50 to fund its clinical trials as well as commercial applications.

However, commercial application has been faced with a series of problems, for example, a legal opinion that proposed that the bonds exempted from the tax could not be used for funding research in which a state would have a share of the profits made by the research. In March 2006 a new issue emerged. Patent holders wanted the researchers to pay some fees for using their patents to do the research. Funnily, this debate resulted from a clash between two states, WARF of Wisconsin and CIRM of California.

In short, it is important to realize that the federal funding of stem cell research is meant to build up new medical horizons that may pay off holders of rights that are already in place.  Recently, the Supreme Court came to an agreement that was more favorable to researchers who were in need of approval by a federal regulatory body such as FDA.

This exemption was intended to ease the effects of previous claims for example, what Wisconsin said about California. But this doesn’t mean that the expectations should be set too high. One question remains, will the state be in a position to fund an embryonic stem cell therapy that is FDA approved in the coming ten years? By what is going on, one might expect positive results. However, it is time to eliminate the possibilities of obstructions along the way.

 

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