Stem Cell Therapy May Offer an Effective Parkinson’s Disease Treatment

The Parkinson’s disease has affected many people in the past and it still startles to know that this disease is still affecting millions of people across the globe. Doctors have been treating only the symptoms of this disease as there is no known cure of the Parkinson’s disease. Recently there has been lots of research on the field of integrative regenerative medicine to help in treatment of this disease. The stem cell therapy is one of the ways that have been investigated by researchers to establish if there is a possibility of this disease having a known cure which is effective.

Despite the fact that the Parkinson’s disease has no known cure, the cause of this disease is known. This disease is caused by the continued loss of dopamine-producing cells in the brain. Dopamine is a crucial brain chemical that helps to regulate movement and emotional responses among other functions.

When a person is suffering from this disease, he will suffer deficiency of dopamine. The Parkinson’s disease is known to target and kill dopamine-producing nerve cells, or neurons, in part of the brain called the substantia nigra. The effects of Parkinson’s disease on the nerve cells of the brain may be the reason for such problems in sleeping, motivation and thinking that Parkinson’s disease is known for but also it has been linked to the linked to the formation of clumps of a protein called alpha-synuclein in the brain. These abnormal protein clumps are called Lewy bodies and are dangerous in the body.

Continued death of the nerve cells results in Parkinson’s patients developing tremors and rigidity, as well as slowed movements. Other conditions that these patients will suffer from as a result of continued death of the nerve cells in the brain includes depression, sleeping disorders, dementia and even constipation. However dementia may be suffered at a much later stage when the damage on the nerve cells has spread widely. They may also lose their sense of smell.

Parkinson’s Disease

Due to the fact that depletion of dopamine causes Parkinson’s disease, doctors have been utilizing treatments that are useful in boosting the levels of dopamine din the brain. One of the most commonly used treatments is the use of a drug known as the Levodopa. This drug has been in use since 1960s when it was discovered. It works in a manner that supplements dopamine levels as it converts into dopamine while in the body. In this case the drug Levodopa stands in for the damaged neurons that ought to produce dopamine. Currently there are also other drugs that are used as dopamine to stimulate the nerve endings. Patients may also go through some therapies and put on special diets all aimed at improving the dopamine levels. In case the disease has advanced a patient may have to be treated through surgeries which may include deep brain stimulation with implanted electrodes. however, the treatments that have been mentioned above only work to mitigate on the effects of the symptoms of Parkinson’s disease but do not slow down or reverse the damage that the disease cause on the nerve cells in the brain. It has also been reported that even with the above treatments it reaches a time when the patient’s condition will deteriorate. There has also been a problem with early detection of the disease as mostly the disease is diagnosed lately after a patient has lost most of his dopamine and the nerve cells in the brain are already damaged. It is with the view of seeking a whole treatment for the disease that scientists began research on the ability of the stem cells to treat Parkinson’s disease.

The stem cell therapy may help

Parkinson’s disease is a dark medical field, its immediate cause isn’t known but scientists have today known which part of the brain is affected by this disease as well as the cells that are often affected by the disease. the stem cells which are known replicate several times giving rise to new cells are already being used to grow dopamine producing nerve cells in laboratories to aid the study of this disease. The stem cells are majorly used in the labs when the genetic cause of the disease is known. The disease destroys cells but through stem cells therapy, the damaged cells can be replaced by healthy new cells of the same type.

Research studies of 1980-90s bred hope

Parkinson's Disease In 1980-90s researchers worked to find out if the cell replacement therapy could be used to quell the harmful effects of the Parkinson’s disease. The findings of these researchers have since been a foundation upon which current researchers increase the scope of their study on the effects of cell replacement therapy on the Parkinson’s disease. Particularly, Swedish, American and Canadian researchers have transplanted the developing nigral dopamine-producing neurons from human fetuses into animals and human patients with Parkinson’s disease. In these studies there were some great improvements while in other cases there were only modest changes.

A new study has since resurfaced. This study is much larger in scope and will include clinical trials. The study titled TRANSEURO aims at addressing the issues of consistency in efficacy as well as reduction in side effects associated with stem cell transplant. There is optimism that stem cell transplant to replace the damaged nerve cells could help in fighting this disease. Dr. Dalal Akoury (MD) is an expert in integrative medicine and a founder of AWAREmed Health and Wellness Center located at Myrtle Beach South Caroline. Visit her for more information on most lifestyle diseases.