Cardiac toxicity treatments prevention

Cardiac toxicity treatments prevention with the professionals
Cardiac toxicity treatments prevention: The heart muscles
The cardiac toxicity treatments prevention is that important that we must do all it takes to embrace. We can only be safe from dangers of cardiac toxicity complications if the preventive approach is given a chance. Experts at AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD reiterates that all heart problems can be prevented by changing our lifestyle and putting drugs away. Nonetheless, where we already have the problem, we can use the following treatment options:
Limiting cumulative dose of drugs
One of the ways to prevent cardiac toxicity is by limiting cumulative dose of drugs that damage the heart, and more so the anthracyclines. We have a defined amount of doxorubicin that can be given with a lesser risk of complications, like for instance if your total dose of doxorubicin is less than 550mg/m2, you may just have about 1% of experiencing cardiac toxicity. On the other hand, when your total dose of doxorubicin is said between 560mg/m2 and 1155mg/m2, your risk is likely to go up to 30%.
Besides that experts have also established that individual patients will tolerate differently the medication of doxorubicin. Some patients may receive high doses of doxorubicin without ever developing heart damage while some have problems at relatively low doses of even less than 550mg/m2 total dose. These variances are all applicable when making effort in preventing the prevention and treatment of cardiac toxicity.
Cardiac toxicity treatments prevention: Administration process
It has been noted in certain cases that there is some supporting evidence that the method of drug administration may affect the risk of cardiac toxicity. Rapid administration of drugs, for instance, may result in high blood levels, which is likely to cause more heart damage than if the same quantity of drugs given over or spread over a longer period of time. In other words giving smaller doses of the drug more frequently can be a perfect prevention and Treatment of cardiac toxicity since it will be instrumental in decreasing the toxicity compared to large doses of drugs at longer intervals.
Cardiac toxicity treatments prevention: Liposomal anthracyclines
The risk of cardiac toxicity from anthracyclines has been reduced by making them in a different way. Liposomal anthracyclines have been encapsulated or enclosed in a liposome, a tiny globule of fat. Because of its capability to hide the drug in fat, it is able to stay in the body much longer because the immune system doesn’t target it for elimination and the liver doesn’t break it down as quickly either. The currently ongoing studies indicate that the risk of heart problems is considerably lower with liposomal doxorubicin formulations than with conventional doxorubicin. Types of liposomal anthracyclines include: Liposomal daunorubicin (DaunoXome®) and Pegylated liposomal doxorubicin (Doxil®)
Pegylated liposomal doxorubicin has been studied most extensively and has demonstrated the most significant reductions in heart problems. Pegylated liposomal doxorubicin has shown a similar anti-cancer effect to doxorubicin, but with less cardiac toxicity. Finally, understanding preventive treatment approach of cardiac toxicity may be hard for many and if you are, then you may want to call doctor Dalal Akoury MD a veteran professional in preventive treatment approach and she will be of great help for you.
Cardiac toxicity treatments prevention: The heart muscles
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