Stem Cells: The New Medicine Medical Research Has Provided

June 8, 2015

Stem Cells: The New Medicine

Stem cell research has been conducted for many years. With stem cells we can now have a better understanding of how organisms that are complex develop from something simple as a fertilized egg. In a laboratory setting, researchers are able to follow up the process of stem cells division into specialized cells that make up the brain, bone and skin as well as other types of cells.

The process involves identifying mechanisms and signals that determine whether or not a stem cell will differentiate into something complex. Understanding will help us understand which processes control the normal cell and organ development.

The stem cell research has been triggered for years by development of serious medical conditions such as birth defects and cancer which often are as a result of abnormal growth and development of cells. Wen cells do not mature, divide and differentiate as they should then conditions such as cancer are likely to develop. A better understanding of molecular and genetic controls of the process of cell division and differentiation will yield more information as to why these conditions come to be and in the process new approaches can be sort. This is an important goal in research on stem cells.

What is a stem cell?

A stem cell is basically a cell that has not reached maturity and one that can potentially become specialized into different cells types in the boy for the formation of different body organs. Stem cells exist in two types: embryonic stem cells and adult stem cells. Embryonic stem cells come to be during division of a newly fertilized cell. When these stem cells divide, they are differentiated to become any type of cell in the body that is required for the formation of different body organs as the foetus develop in the womb.

Adult stem cells on the other hand are very different from embryonic stem cells. These types if stem cells are found I already developed tissues. They are therefore found in both children and infants. These stem cells are not developed or a fertilized egg but are found later when different tissues have already developed. These types of stem cells act like replacement cells. This means that they undergo division regularly in order to replace worn out, dead or lost cells. They are specialized to take the place of cells that have been lost or those that have died. Adult stem cells can be found in tissues of the body such as blood, brain, bone, skin and muscle. N as much as research on stem cells has been going on for long, the research has not been able to yield much result due to the inability to develop and differentiate these cells in a laboratory setting.

The medical breakthrough in stem cells research

As seen much earlier, stem cells are immature cells that have the tendency to develop and specialize into any type of cells. This being the case, researchers have tried to use stem cells in understanding and dealing with medical conditions such as birth defects and different types of cancers like leukemia. Because stem cells can be specialized into any type of cells they have the potential of treating disease and other disorders.

Today stem cells research procedures are used life-saving options for patients suffering from lymphoma, leukemia, some types of tumors and other disorders of the blood.

stem cells

Bone marrow transplant: For many years bone marrow transplant has been used tin treatment of diseases like leukemia. Bone marrow transplant involves removal of a donors bone marrow stem cells and replacing them with those of a sick patient. If the procedure proves successful, the bone marrow form a healthy donor migrates into the bone marrow of the patient. The healthy bone marrow will then begin producing healthy white blood cells which will end up replacing the abnormal cells in the patient. His s one of the major breakthroughs in stem cells transplant hat has seen many leukemia patients get a second chance.

Peripheral blood stem cells (PBSCs): naturally may of the blood stem cells are fund n he bone marrow, however a small number of these can be found n he blood stream. The process of obtaining stem cells from the bone marrow is usually a difficult process. Since stem cells are also resent in the blood, they can be obtained with ease form drawn blood making the process of obtaining stem cells easier. The only problem is that, stem cells in the blood stream exist sparsely in the blood stream which can prove difficulty while trying to extract enough of them for a transplant.

Umbilical cord stem cells transplant: the umbilical code s normally discarded as a waste product of the process of birth. However research shows that the blood found in the umbilical cord is rich in stem cells. These can be harvested and used to treat patients of cancer and other conditions of cell defects. These stems cells have been used to treating the same conditions as those treated by stem cells of the bone marrow and PBSCs.

Stem cells transplant is proving to be a promising approach to health conditions such as lymphoma and leukemia. You can tap into these benefits. Dr. Dalal Okoury is an expert in integrative medicine. Don’t also forget to attend the Integrative Addiction Conference 2015. The conference will provide a once in a lifetime opportunity of approaches to identifying and treating patients of addiction. Visit http://www.integrativeaddiction2015.com for more information about the addiction conference.

Stem Cells: The New Medicine Medical Research Has Provided

Current Stem Cell Treatments for Orthopedic Conditions

March 8, 2015

Current Stem Cell Treatments for Orthopedic Conditions

The stem cells have a unique ability to divide and become more specialized cells forming cells like bone, blood, or muscle. It is this ability that makes them attractive agents in many areas of medicine. They can therefore be used to fight very many diseases in the regenerative medicine. Another advantage of stem cell therapy treatments is that autologous stem cell transport is made possible. This means that a person may be treated by doctors harvesting the stem cells from the patient and having the stem cells reimplanted into the same patient after finding out what was lacking in the patient. This reduces risks of infection as well as rejection which are helpful to the patient.

Today the stem cell therapy has become the game changing approach to treatment of orthopedic conditions. The ability of these stem cells to differentiate into more specialized cells has made them a valuable target in treatment of musculoskeletal conditions. Particularly the use of bone marrow stromal cells has attracted the attention of researchers who are in pursuit of finding out how these stem cells can be applied to end human misery caused by some diseases.

Stem cells are a unique type of cells, unlike the other cells in the body the stem cell have the ability to self-renew, they have the ability to divide several times giving rise to differentiated cells which are suited for specific functions hence can be used to replace or regenerate worn out cells in the body causing pain and discomfort. They can form cardiac, liver, fat, bone, cartilage, nerve, and connective tissue cells among other more specialized cells. Autologous stem cell therapy harnesses the regenerative power of your body’s own stem cells as a treatment option for degenerative orthopedic conditions.

body_skeleton

Today there are hospitals that have embraced the use of stem cells therapy in treating orthopedic conditions that were rather not easily treated in the past. They offer this autologous stem cell therapy, which embraces the regenerative power of mesenchymal stem cells to give patients another treatment option for dealing with orthopedic conditions such as osteoarthritis and other degenerative joint conditions. Patients who have the following diseases can benefit from stem cell therapy;

Degenerative Joint Changes, Including Osteoarthritis
Disc-related Back Pain
Meniscus Tears
Non-Union Fractures
Avascular Necrosis
Bone Loss
Cartilage Defects
Osteonecrosis
Tendonopathies

Orthopedic Areas in which Stem Cell Therapy is applicable

Spine – the stem cell therapy is applicable in treatment of the degenerated intervertebral disk which is known to cause pain and morbidity to many patients. The stem cell therapy brings into the field of regenerative medicine some bits of effectiveness. In treatment of spine, patients who fail to respond to conservative medicine are left with one option-surgery that may have limited success and is also very invasive. Cell-based tissue treatments, including mesenchymal stem cell injections for degenerative disc subjects have been shown to diminish the incidence of low back pain, with clinical results noting improvement in back pain and regeneration of the disc tissue. In cases where spinal fusions are necessary, the use of stem cells through bone marrow aspirate has shown greater success in obtaining fusion through bone formation as compared to standard fusion techniques. Daily the number of institutions using the stem cell therapy to treat orthopedic conditions is increasing.

Articular Cartilage – when the articular cartilage is damaged, the potential to repair it are limited and this can often lead to arthritic diseases many years later. This damage may be caused by injury. The vulnerability of the articular cartilage makes it important for it to be well handled in cases of injury. studies that have been done on the applicability of the stem cell therapy to repair damaged articular cartilage have shown that stem cell therapy have favorable outcomes in this area than current techniques of micro fracture and autologous chondrocyte implantation. Most studies use mesenchymal stem cells derived from the bone marrow.

Osteonecrosis – Osteonecrosis or avascular ischemia of the hip can be associated with progression to an advanced arthritic joint. Standard treatment for osteonecrosis has included cord decompression with limited results. Stem cell therapy holds key to success in this area of orthopedic treatment. Studies on this area have shown that patients treated with mesenchymal stem cells improved than those treated with cord decompression.

Bone – some damages on the bone may require transplantation of the bone plus other bone components. This is the effective way of restoring the bone structure. Being that the mesenchymal stem cells can be differentiated into bone cells and be used to replace the damaged bone components, stem cell therapy becomes the most appropriate treatment for bone damage.

Tendons and Ligaments – Autografts, allografts, and resorbable materials have been used to repair defects in tendons and ligaments however these methods puts the life of the patient at risk which may include formation of scars, donor morbidity and even tissue rejection. With autologous stem cell transplant all these risks are alleviated plus the mesenchymal stem cells may also be used alongside tissue allografts as this gives better results by improving the biochemical properties of the tissue allografts.

Stem cell therapy is a promising treatment for orthopedic diseases; you may tap into the unique medicinal properties of the stem cells to help you beat orthopedic conditions. Visit us at AWAREmed Health and Wellness Resource Centre at Myrtle Beach, South Carolina. Dr. Dalal Akoury (MD) an expert in integrative and regenerative medicine will be able to help.

Current Stem Cell Treatments for Orthopedic Conditions

Stem Cell Therapy Is Non-Invasive Safe and Gives Fast Results

March 4, 2015

Stem Cell Therapy Is Non-Invasive Safe and Gives Fast Results

Stem cell therapy is an option to patients with degenerative diseases but would rather have treatments that are non-invasive. in fact the very nature in which stem cells work makes it a better option to patients as it has few risks and side effects are rarely life threatening (if there is). The stem cell therapy is applicable to those fighting aging, autism, diabetes, orthopedic conditions among other diseases. autologous stem cell transplant allows the cells harvested from a patient to be used in the same patient in fact on the day, this is because the mesenchymal stem cells that have the ability to form more differentiated cells like bone cells , liver cells, heart cells, muscle cells among other are available in enough amounts in the adipose tissues as well as in the bone marrow therefore there is no need to keep the harvested cells in the petri dish in the laboratory to be cultured so as to be able to serve a desired purpose. They can be harvested on the same day and be reimpplanted into the target area in the patient’s body on the same day. Autologous stem cell transfer is a safe and effective procedure and strategy to treatment of diseases since the cells used are from the patient and therefore there is no risk of donor shortage, donor morbidity, cell rejection and even contacting diseases from the donor.

stem cell therapy

Autologous stem cell therapy is non-invasive and gives fast results

Autologous stem cell transplant refers to a case where the stem cells harvested are from the patient to be treated. Normally, the body has stem cells in the bone marrow, in muscle tissues and also in the adipose tissues. These stem cells turn into red blood cells, white blood cells, or platelets to help your body stay healthy. However there are situations when the amount of stem cells in the body is not enough to keep you healthy. This may be caused by some diseases like multiple myeloma or by aging. When this happens there will be need for supplementing the amounts of the stem cells so that they can be able to offer protection to your body. This calls for stem cell transplant which may be done by placing healthy stem cells in the patients’ body through an IV to restore the normal functions of the stem cells. At times the stem cells may be harvested from outside the body especially from placentas after successful normal delivery, but mostly the stem cells are harvested from the patients’ body since autologous transplant is safer and time saving. Autologous stem cell transplant is safer since the cells are from the body and therefore there is no risk of them getting rejected neither to induce unpleasant allergic reaction. Autologous stem cell transplantation may provide the best outcome for patients, since autologous cells are readily available and do not entail prolonged hospital stays or sustained immunotoxic therapy. Among autologous adult stem cells, mesenchymal stem cells therapy has been applied with varying degrees of success in both animal models and in clinical trials.

Stem cell therapy tackles myriads of ailments

The medicinal properties of the stem cells have seen it being used for treatment of myriad ailments or as therapy for many diseases that are not even treatable. for the cases of these diseases that are not treatable the stem cell therapy helps to alleviate on the dangerous symptoms of the diseases and offer comfort as well as lengthen the lives of those who are victims of these diseases. needless to mention , the stem cell therapy has become a crucial component of regenerative medicine with many researchers still working around the subject to find out how its applicability can be useful in treating lifestyle diseases that have become a problem to this generation and many generations to come. The stem cell therapy has been proposed as an effective therapy in cases of autism, diabetes, arthritis and cancer among other diseases.

Mesenchymal stem cells holds key to regenerative medicine

Researchers have found a specific stem cell type to be very important in stem cell therapy to fight aging and other degenerative diseases as well as orthopedic conditions. These stem cells that are considered to be the most important are known as the mesenchymal stem cells. The Mesenchymal stem cells are found in the bone marrow, the circulating blood as well as in adipose tissues. Mesenchymal stem cells are the most important stem cells for orthopedic purposes as they help to repair and replace damaged tissues hence restoring the cell functions.

The Mesenchymal stem cells are very helpful, however as a person ages the number of mesenchymal stem cells in the bone marrow gets depleted and this is what results in aging and increases a person’s chances of suffering from joint diseases and other orthopedic conditions. It is therefore very logical to go through a stem cell therapy as an anti-aging procedure that will also help on mitigating on the adverse effects of aging. Today these stem cells have now become an integral part of regenerative medicine. there is a lot that can be done with stem cell therapy, Visit us at AWAREmed Health and Wellness Resource Centre at Myrtle Beach, South Carolina. Dr. Dalal Akoury (MD) an expert in integrative and regenerative medicine will let you know how you can benefit from stem cell therapy.

Stem Cell Therapy Is Non-Invasive Safe and Gives Fast Results

Safe Autologous Stem Cell Transplant for Diabetes

March 1, 2015

According to a recent WHO report, diabetes is one of the top ten leading causes of death worldwide; in 2012 the global prevalence of diabetes was estimated to be more than 10% among adults. The most prevalent type of diabetes is the type 2 and it is rampant in adult population. It is reported that diabetes is the leading cause of renal failure and blindness in developed countries, a person suffering from diabetes also has high chances of having a limb amputated. The risk of limb amputation is 10 times higher in diabetic patients. It is also known that most diabetic patients develop hypertension and cardiovascular diseases, which account for high rates of morbidity and mortality among adult patients. Most patients receive treatment through oral medication but this is also dangerous since after sometime they become insulin dependent. Oral insulin medication is also not so effective since exogenous insulin cannot provide the tight glycemic control exerted by the pancreas-derived insulin secretion. Due to these myriad problems stem cell therapy can be very useful in replacing the affected cells and restore normal cell function normalizing insulin levels in the long run.

What is autologous stem cell transplant?

The body has stem cells in the bone marrow, in muscle tissues and also in the adipose tissues. These stem cells turn into red blood cells, white blood cells, or platelets to help your body stay healthy. However there are situations when the amount of stem cells in the body is not enough to keep you healthy. This may be caused by some diseases like multiple myeloma or by aging. When this happens there will be need for supplementing the amounts of the stem cells so that they can be able to offer protection to your body. This calls for stem cell transplant which may be done by placing healthy stem cells in your body through an IV to restore the normal functions of the stem cells. at times the stem cells may be harvested from outside the body especially from placentas after successful normal delivery, however when this stem cells are sourced from within the body of the patient then it is referred to as autologous stem cell transplant. Autologous stem cell transplant is safer since the cells are from the body and therefore there is no risk of them getting rejected neither to induce unpleasant allergic reaction.

autologous stem cell transplant

How stem cells collected

In autologous stem cell transplants, the doctors use peripheral blood stem cell transplantation. With peripheral blood stem cell transplantation, the stem cells are taken from blood. The growth factor G-CSF may be used to stimulate the growth of new stem cells so they spill over into the blood. G-CSF is a protein that is produced naturally in the body. The blood is removed from a vein and passed through a machine that separates the stem cells. The machine then returns the remaining blood through a needle in the person’s arm or through a central venous catheter. This way of collecting stem cells is called apheresis. In adults, most autologous transplants use stem cells from blood. In a child, the decision whether to use cells from the bone marrow or the blood depends on the size of the child.

Mesenchymal stem cells work best for diabetes

In the past cell based therapy as used in treatment of diabetes began by use of islet transplantation have been successful in providing a source for insulin secreting cells. However this method has had its share of failures and disadvantages that created a vacuum that doctors hoped to be filled by a better cell based therapy. Some of the downs of the islet transplantations included; limited donors, graft rejection, the need for continued immune suppression and exhaustion of the donor cell pool. the search for a more reliable and sustainable source of insulin secreting cells made stem cell therapy a target as a promising alternative for islet transplantation in diabetic patients who fail to control hyperglycemia even with insulin injection. Autologous stem cell transplantation may provide the best outcome for those patients, since autologous cells are readily available and do not entail prolonged hospital stays or sustained immunotoxic therapy. Among autologous adult stem cells, mesenchymal stem cells therapy has been applied with varying degrees of success in both animal models and in clinical trials.

autologous stem cell transplant Cell-based therapies for diabetes mellitus had achieved lots of success with the application of islet transplantation from cadaveric donors, and the success of the Edmonton protocol back in 1999. Despite the success of islet transplantation in fighting diabetes more so for type 1, there were some drawbacks for example there was need to use immunosuppressive regime so as to favor graft acceptance and prevent rejection. It is with these loopholes that researchers sought to find better treatment with mesenchymal stem cells. Stem cell therapy is a solution to some of the drawbacks of islet transplantation especially the shortage of donors. Autologous stem cell therapy allows for a person’s on organs to be used in the transplant.

In autologous stem cell transplant the most effective mesenchymal stem cells are used to differentiate into insulin producing cells. The mesenchymal stem cells can be harvested in the bone marrows or in the adipose tissues where they are found in plenty. The mesenchymal stem cells have very many advantages when used as they have a high capacity to self-replicate and differentiate to bone and fat-forming cells and other tissue cells. They maintain the capacity of multilineage differentiation potential, both within and across lineage barriers. They are easy to cultivate and expand, and maintain pluripotentiality after prolonged culture conditions. For more information on diabetes, Visit us at AWAREmed Health and Wellness Resource Centre at Myrtle Beach, South Carolina. Dr. Dalal Akoury (MD) an expert in integrative and regenerative medicine will be able to help.

Safe Autologous Stem Cell Transplant for Diabetes

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