Fighting opioid addiction compounding pharmacies

February 27, 2016

Fighting opioid addiction compounding pharmacies: Prescription painkillers overdose

Fighting opioid addiction using compounding pharmacies. This can offer an alternative treatment method for all victims.

I believe that at one point of your life you have visited a doctor for help especially when you were having that miserable pain. The doctor on his part was willing to help and he may have prescribed for you some pain killers tabs. And for sure the pain killers worked and you felt better that you were before and so you believed your pains have gone never to come back. One thing that may not be known to you is that of the consequences attached because most of these temporal solutions often lead to drug overdose. When this happens, our problems become more compounded and before we knew it, we are addicted to those drugs and that is why we want to find out how fighting opioid addiction using compounding pharmacies can be of help under such circumstances. Doctor Dalal Akoury and her team of experts from AWAREmed Health and Wellness Resource Center are going to help us unlock the truth about this condition. Stay tune and learn with the experts so that you can take appropriate decision in keeping yourself and loved ones safe.

From experience, doctor Akoury registers that many drugs that causes life devastations to families and communities have actually come from the misuse of official pharmacist and doctor’s prescriptions. The magnitude of this is very worrying across the globe and according to the available statistics in the US alone up to 15,000 people die yearly from overdoses of prescription painkillers. Out of those registered deaths one in ever twenty people of 12 years and above reported using prescription opioids for nonmedical reasons within the last twelve months. Stunningly, enough prescription painkillers were prescribed in the year 2010 to medicate every American adult for 24 hours a day, seven days a week, for an entire month.

Ideally looking at the trend, it may pass as a simple issue of normal over-prescription of painkillers. Nonetheless this in the public health arena the ultimate causes and solutions are just too numerous. That is why the vitality of compounding pharmacies is a unique way in the contribution toward the eradication of this problem says doctor Akoury. They are able to change the medication itself and alter addictive properties through the act of compounding, and hold a vital role in the fight against opioid addiction.

Fighting opioid addiction compounding pharmacies: The vitality of compounding in addiction prevention and treatment

Tackling the global painkiller addiction epidemic requires a well thought approach from all sectors of health care, including but not limited to primary, secondary and tertiary care methods; clinical care approaches and even financiers like insurers working with providers to reduce barriers to addiction treatment that will secure prescription avenues to prevent over-prescription. For compounding pharmacies, more stringent measures to ensure provenance of prescriptions and education for staff to recognize warning signs of addiction, such as filling prescriptions from multiple sources, can be vital in preventing the spread of addiction as well.

When fighting opioid addiction this way, it is important to appreciate that the primary way compounding pharmacies can assist at a patient-level is by applying the tenets of compounding as preventative measures. This (Compounding) is meant to provide a better care for those already struggling with addiction by providing alternative but less-systemic and easier delivery methods tailored to specific individual patient needs. These measures fundamentally reduce the risk of addiction for all patients and will directly benefit individuals with a history of or tendency to opioid painkiller addiction.

Fighting opioid addiction compounding pharmacies: The pill form of opioids

Most of the opiates being abused by addicted patients are in pill form. These are easy to open up, transport, and also provide the brain toxicology-altering high that addicts seek. Experts at AWAREmed Health and Wellness Resource Center are categorical that the easiest ways to fight addiction is to eliminate the reward from the situation entirely. This can be done by compounding oral painkillers into up-to-date creams and gels where possible with this the compounding pharmacies can lower the risk of addiction significantly. The good news about this is that not only do topical compounds deliver more localized pain relief and cause fewer complications due to lower absorption rates, a topical compound does not alter brain state the way oral opioids do when delivering the much needed high by users.

Besides that doctor Akoury registers that compounding pharmacies can also provide alternative options for traditional painkillers which are typically reserved for patients who have allergies to certain medications thereby necessitating the need for compounded alternatives, using a painkiller alternative for Vicodin or Oxycontin that can lower prescriptions for the highly addictive and readily available painkillers. Patients or doctors with patients who are working on overcoming drug addiction can also work with a compounding pharmacy to help with “tapering,” or the act of slowly reducing ingested levels of opioids to safely treat the body’s addiction without abruptly cutting off supply.

Finally according to the information available with the public health sector, it is evident that compounding pharmacies contribute a lot to the fight against opioid addiction on both fronts at the macro level by working with researchers and other health care professionals to understand the broader development of these public health issues; and at the micro level by working with patients and physicians to use compounding to reduce the addictive properties of medications. Owing to the nature of treatment involve with painkillers overdose, this may be difficult for you to understand, nonetheless we have taken it up on ourselves (AWAREmed Health and Wellness Resource Center) to be of help to you in the most professional way you deserve. If you are struggling with any kind of addiction we want to let you know that help is on the way and you can be well again in a very short time at affordable rates. All you need to do is to schedule for an appointment with doctor Dalal Akoury today by calling her on the phone numbers on this site and she will be able to attend to you professionally.

http://regenerativepotential.com/integrativeaddictionconference/

Nicotine Addiction in Females

January 13, 2015

Role Of Progesterone In Nicotine Addiction In Females

Progesterone is a found in good quantities in women and is often thought of as a female hormone. this hormone is important for the regulation of ovulation and menstruation. however current research findings have indicated that this hormone has a role in inhibiting nicotine addiction.

today many people are using drugs with nicotine content and nicohtine addiction is on the rise. it has been causing death that could rather be prevented especially in the developed countries. this stimulant is used by all genders and is appreciated for a feel of high sensation and relaxation after sometime but researchers have noted that women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. However the mechanism of gender differences in nicotine addiction is not yet clear, but there is evidence that endorses the suggestion that progesterone may protect females against nicotine addiction unlike estrogen that some researchers have linked to enhanced vulnerability in females to nicotine addiction. Therefore, progesterone may have therapeutic use for nicotine addiction, especially in female smokers. Researchers are working to establish the reason for this gender variation in nicotine addiction and the discovery will provide a greater understanding of the role of progesterone in nicotine addiction. this is important not only from a treatment purposes but also from a prevention perspective. The changes in hormones in the body of women such as those that occur at adolescence and during pregnancy and following birth. The changes in hormones that are also caused by hormonal manipulation like using methods of hormonal birth control may all contribute to changes in vulnerability to nicotine addiction.

Here, we will explore in reference to recent evidences from clinical studies how progesterone affects the health of a woman in relation to nicotine addiction. Depending on the data already availed from past researches we will find out the effects of progesterone during the initiation stage and even during the later stages of nicotine addiction process as a potential relapse prevention treatment.

Several studies have indicated that in spite of the public knowledge that nicotine addiction can be dangerous to one’s health, tobacco use has been on the rise especially on young women and teens. In a 2007 study results on National Survey on Drug Use research done by Substance Abuse and Mental Health Services Administration often shortened as SAHMSA found that Females aged 12–17 are also more likely than males initiate smoking. It has also been found out that women take shorter time to develop tobacco dependence syndrome after their initial use of tobacco.

Similar reports of enhanced vulnerability in females versus males have been reported among adult smokers. For example, among adults (18 years and over), although more men than women smoke, women take less time to become dependent after initial use, report shorter and less frequent abstinence periods and smoke for longer periods of time in their lives compared with men with the median cessation age of 33 years for males versus 37 years for females. This finding was reported by a research done by Pierce and Gilpin in 1996 in a study titled: How long will today’s adolescent smoker be addicted to cigarettes?

Of all the studies that have been available on tobacco use it has been found that women are more vulnerable to nicotine addiction as they also appear to respond less favorably to smoking cessation treatments.

Donny and Clark study on rats

A preclinical study on rats done by Donny and Clark with other researchers provided information that is Consistent with the above findings. In preclinical studies, adolescent and adult female rats showed faster acquisition of intravenous nicotine self-administration and higher break points on a progressive-ratio schedule compared with adolescent and adult males. Similarly, female mice showed a greater preference for nicotine in a two-bottle choice task compared with male mice indicating greater sensitivity of females to nicotine’s reinforcing effects. These studies point to important gender differences in initiation and maintenance of nicotine use that may contribute to smaller gains in curbing nicotine addiction in women.

Progesterone and GABA receptors

Several research findings point out that Progesterone and its metabolites interact with multiple neurotransmitter receptors including GABA, glycine, sigma1, kainate, serotonin3, and nicotinic cholinergic receptors. However, most relevant for nicotine addiction are interactions with GABA. Progesterone’s active metabolites, pregnanolone and allopregnanolone, have positive modulatory effects on GABA receptors which enhance GABAergic transmission. GABA is the main inhibitory neurotransmitter in the brain and has significant influence on multiple central nervous system (CNS) function. The positive modulatory effects of progesterone metabolites on the GABA receptors have been proposed to weaken drug reward. Remarkably, the effects of progesterone and its metabolites on GABAergic signaling vary with menstrual cycle phase and at hormone transition phases including during adolescence and during pregnancy. For instance, during puberty, allopreganolone’s effects on GABAergic transmission are opposite to those seen before and after puberty with results showing a reduction in GABAergic transmission.

nicotine addiction It has also been reported that progesterone also affects signaling at nicotinic receptors. Specifically, both progesterone and allopregnanolone are negative modulators of the α4β2 nicotinic receptors. Progesterone has also been reported to increase mRNA expression of α5 nicotinic receptors.

Despite the research findings that have been published on this issue, the available literature is still insufficient to anchor a strong decision on the use of progesterone hormone in fighting nicotine addiction. Dr. Dalal Akoury (MD) of AWAREmed Health and Wellness Center is an expert in integrative medicine for addiction. Call her on (843) 213-1480 for help.

Role Of Progesterone In Nicotine Addiction In Females

Progesterone And Nicotine Addiction

January 7, 2015

Research Shows Progesterone Influences Nicotine Addiction in Women

Nicotine is a common substance in certain drugs. In fact we interact with nicotine most of the time without even stopping to think that it is really an addictive substance. Nicotine can be found in tea but again the level of nicotine will be different depending on which drug you are using. However nicotine has always been associated with tobacco and this is because it forms a bigger content of tobacco. Unknown to many, nicotine is the addictive substance in the tobacco and so should be avoided as much as other drug contents that are often considered more dangerous. Today, Nicotine addiction is on the rise and it continues to be the main cause of preventable death in developed countries. Despite of use of tobacco by people of all genders, it has been found that women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. While the mechanism of gender differences in nicotine addiction is not yet clear, evidence suggests that while estrogen may underlie enhanced vulnerability in females, progesterone may protect females. Thus, progesterone may have therapeutic use for tobacco addiction, especially in female smokers. Researchers are working to establish the reason for this gender variation in nicotine addiction and the revelation will pose a greater understanding of the role of progesterone in nicotine addiction is important not only from a treatment purposes but also from a prevention perspective. The changes in hormones in the body of women such as those that occur at adolescence and during pregnancy and following birth. The changes in hormones that are also caused by hormonal manipulation like using methods of hormonal birth control may all contribute to changes in vulnerability to nicotine addiction.

In this article we will explore in reference to recent evidences from clinical studies how progesterone affects the health of a woman in relation to nicotine addiction. Depending on the data already availed from past researches we will find out the effects of progesterone during the initiation stage and even during the later stages of nicotine addiction process as a potential relapse prevention treatment.

Several studies have indicated that in spite of the public knowledge that nicotine addiction can be dangerous to one’s health, tobacco use has been on the rise especially on young women and teens. In a 2007 study results on National Survey on Drug Use research done by Substance Abuse and Mental Health Services Administration often shortened as SAHMSA found that Females aged 12–17 are also more likely than males initiate smoking. It has also been found out that women take shorter time to develop tobacco dependence syndrome after their initial use of tobacco.

Similar reports of enhanced vulnerability in females versus males have been reported among adult smokers. For example, among adults (18 years and over), although more men than women smoke, women take less time to become dependent after initial use, report shorter and less frequent abstinence periods and smoke for longer periods of time in their lives compared with men with the median cessation age of 33 years for males versus 37 years for females. This finding was reported by a research done by Pierce and Gilpin in 1996 in a study titled: How long will today’s adolescent smoker be addicted to cigarettes?

Of all the studies that have been available on tobacco use it has been found that women are more vulnerable to nicotine addiction as they also appear to respond less favorably to smoking cessation treatments.

Preclinical studies on rats

A preclinical study on rats done by Donny and Clark with other researchers provided information that is Consistent with the above findings. In preclinical studies, adolescent and adult female rats showed faster acquisition of intravenous nicotine self-administration and higher break points on a progressive-ratio schedule compared with adolescent and adult males. Similarly, female mice showed a greater preference for nicotine in a two-bottle choice task compared with male mice indicating greater sensitivity of females to nicotine’s reinforcing effects. These studies point to important gender differences in initiation and maintenance of nicotine use that may contribute to smaller gains in curbing nicotine addiction in women.

Progesterone interacts with GABA receptors

Several research findings point out that Progesterone and its metabolites interact with multiple neurotransmitter receptors including GABA, glycine, sigma1, kainate, serotonin3, and nicotinic cholinergic receptors. However, most relevant for nicotine addiction are interactions with GABA. Progesterone’s active metabolites, pregnanolone and allopregnanolone, have positive modulatory effects on GABA receptors which enhance GABAergic transmission. GABA is the main inhibitory neurotransmitter in the brain and has significant influence on multiple central nervous system (CNS) function. The positive modulatory effects of progesterone metabolites on the GABA receptors have been proposed to weaken drug reward. Remarkably, the effects of progesterone and its metabolites on GABAergic signaling vary with menstrual cycle phase and at hormone transition phases including during adolescence and during pregnancy. For instance, during puberty, allopreganolone’s effects on GABAergic transmission are opposite to those seen before and after puberty with results showing a reduction in GABAergic transmission.

It has also been reported that progesterone also affects signaling at nicotinic receptors. Specifically, both progesterone and allopregnanolone are negative modulators of the α4β2 nicotinic receptors. Progesterone has also been reported to increase mRNA expression of α5 nicotinic receptors.

In conclusion

Progesterone may avail a skeleton for nicotine treatment in women but more research need to be done on this issue so as the potential of nicotine addiction with progesterone can be examined. Dr. Dalal Akoury (MD) of AWAREmed Health and Wellness Center is an expert in integrative medicine for addiction. Call her on (843) 213-1480 for help.

Research Shows Progesterone Influences Nicotine Addiction in Women

Natural Body Restoration Before and After For Chemotherapy

October 13, 2014

Why you need to prepare for chemotherapy

Chemotherapy is a form of cancer treatment that makes use of drugs to kill the cancer cells in the body. Usually, the drugs are made of highly active chemical compounds that directly act on the cancer cells. The nature of the drugs and the way they function in the body presents a number of changes to a patient. Also, the fact that the treatment usually runs for a considerable length of time makes it necessary for one to be fully prepared for it. Therefore, it is important that a patient is fully prepared before chemotherapy is administered.

Ways of preparing for chemotherapy

There are several ways in which a patient can prepare for chemotherapy. The preparation usually follows some basic approaches.

Getting sufficient rest

It is important for one to get sufficient rest in the weeks that precede the treatment. The basic reasoning behind this is simple. Usually, one gets anxious and restless in the days prior to the treatment. Such an emotional state triggers biological responses in the body. When this happens, a person remains in an agitated state throughout the treatment. When the treatment is administered to a person who is already under emotional stress, the side effects of the drugs tend to be increased. It is therefore very important for one to get enough sleep in the weeks prior to undergoing the therapy.

Chemotherapy

There are several ways in which one can get enough sleep and rest. For example, there are special natural supplements which, when used, can help one sleep well and be fully relaxed before undergoing the treatment. Also, one can get some of the many herbals that are used to induce sleep in individuals. In general, using natural methods to enhance one’s sleep can play a vital role in helping a patient be fully relaxed before undergoing chemotherapy.

Being psychologically prepared

There is always the tendency of patients feeling extremely worried about the effect that the treatment will have on them even before undergoing it. Furthermore, the fact that chemotherapy is a complicated process that takes its toll on the health of a patient makes many people very worried about it. These two factors: fear and worry, can make a patient lose self composure long before the treatment is administered. Therefore, it is important for one to be psychologically prepared for treatment.

Good preparation begins with being fully informed of what chemotherapy is all about, how it will be carried out and the possible side effects that one should expect. This will help one to be fully prepared psychologically before undergoing the treatment.

Being physically prepared

As much as psychological preparation is important, one has to be physically prepared for the treatment as well. Physical preparation takes many different forms. For example, you need to increase your amount of intake of proteins. The reason for this is simple. Proteins perform the all-important function of rebuilding the body. This becomes a critical need in the course of treatment because the drugs used in the treatment kill both cancer and body cells.

Also, physical preparation takes the form of increasing the level of intake of water. This makes the body to be in the right form before one undergoes the treatment.

Why you need restoration after chemotherapy

After successfully undergoing therapy, one’s body is usually weakened by effects of the drugs. Furthermore, there is a buildup of toxic products that are produced by the action of the drugs on cancerous cells in the body. This makes it necessary for one to undergo a comprehensive restoration process after the treatment.

Ways of restoration after chemotherapy

There are several ways in which one can restore the body to its perfect condition after undergoing chemotherapy. The overall objective is to remove all the toxic products that accumulate in the body and repairing cells that have been damaged by the effect of the drugs. This can be done in several ways.

Taking the right kind of foods

Diet plays an important role in restoring the body to an ideal state of health after one has undergone chemotherapy. There are several foods that can help in this course. For example, it is recommended that one increases the amount of fiber in the diet. Fiber is important because it helps one to heal quite fast. Furthermore, the role that fiber plays in the process of digestion can be useful to a patient who has undergone chemotherapy because this will speed up the process of eliminating toxic products from the body. Therefore, one should eat foods that contain a lot of fiber like whole grains and different types of fruits and vegetables.

Chemotherapy

Physical Restoration Of The Body

Here, one needs to develop a good plan for physical exercise and stick to it. The importance of this is that physical exercise helps the body overcome drug-induced fatigue thus speeding up the healing process. One can start with light exercises and progress as time goes by.

Body restoration through the use of fluid

Fluids like water are important components of a body restoration program after chemotherapy. Fluids serve several important functions in the body. For example, they speed up the rate at which waste products are eliminated from it. Since chemotherapy leads to a buildup of toxins in the body, increased intake of fluids is very useful in removing such toxins.

Whether you are preparing for or recovering from chemotherapy, Dr. Dalal Akoury of AWAREmed Health and Wellness Resource Center will be of great help. Spending time with her either before or after chemotherapy will help you be fully prepared for the process and get over its effects, safely, naturally and fast.

Natural Body Restoration Before and After For Chemotherapy

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Opiates And The Risks of Breast Cancer

September 29, 2014

The relationship between opiates and breast cancer has been focused on three important aspects. The first aspect has been what the use of opiates is with regard to cancer in general and breast cancer in particular. The second aspect of this relationship has been whether or not the use of opiates for specific functions with regard to cancer treatment endangers the lives of the patients by contributing to recurrence of cancer long after its successful treatment. The third aspect has been the exact mechanisms by which opiates produce the said effect in the body of patients and what should be done about it. All these aspects are addressed in this article in the sections that follow.

Breast Cancer And The Use Of Opiates

Breast cancer is one of the most common forms of cancer among women in the world. Two reasons for this have been advanced. The first one is that breast cancer is generally associated with estrogen, a special type of hormone responsible for femininity. Since this hormone is predominantly found in women (sometimes in high levels), this makes them completely exposed to possible development of breast cancer. The second one arises from the observed trend of an increasing risk of breast cancer and age among women. There are several underlying reasons for this but the fact remains that with people in general living longer they get exposed to certain health conditions. For women, breast cancer is the common health condition that comes with age.

Opiates have been extensively used in the treatment of cancer as part of modern therapies. The use of opiates is in the form of drugs that are derived from morphine, a common type of plant that represents what opiates are, which is used as an extremely powerful painkiller for cancer patients. The exact mechanism by which opiates (in the form of morphine-based pain killers) works to relieve patients of pain is a complex process. But it suffices to say that the active chemical compound in opiates activates special cells within the nervous system of the patient leading to massive decline in pain sensations. This presents great relief to patients, particularly when one considers the intensity of cancer-induced pain which patients do experience.

Breast Cancer

Opiates And Breast Cancer: The Danger Of Recurrence

There has been considerable concern about the relationship between opiates and cancer recurrence in patients. The concern has been based on the growing discovery that some patients who, in the course of their treatment for cancer used morphine-derived drugs as pain killers, showed signs of the disease recurring after some time. The argument has been that the opiates that are found in the drugs must be responsible for this observed phenomenon.

There are two important things that should be understood from this. The first one regards the exact use of opiates in cancer patients. In practice, opiates are used as pain killers on patients before other forms of therapy, such as surgery, are used. During such times, the drugs are usually administered in heavy doses as a way of dealing with the equally intense pain.

The second one regards the use of the drugs during times when the disease is still in its early stages of development. There have been a number of studies that have sought to demonstrate the exact effect of opiates on cancer cells. It has been shown, with mixed reactions, that opiates do show anti-cancer properties at times and that they can actually be used to inhibit the rate of growth of cancer cells. Although this is so, the efficacy, extent and possible mechanism by which this occurs remains a subject of research.

What has caught our attention is the increasing proof that indeed using opiates as pain killers in patients of breast cancer may contribute to the cancer occurring again in them later.

Ways of recurrence as a result of opiate use in breast cancer patients

There are several ways in which use of opiates as pain killers leads to recurrence of breast cancer in patients. Basically, this ability is understood by the role that the compound plays in the processes of metastasis and angiogenesis. These two processes are critical for the growth and development of cancer. Through angiogenesis, cancer cells are able to derive their own supply of blood from the existing circulatory system, thus fueling their own growth. Similarly, through metastasis, cancer cells are able to spread to other parts of the body via the circulatory system.

Opiates have been found to enhance angiogenesis by their effect on the immune system. Naturally, the body produces special hormones that work to prevent possible development of cancer cells. Use of opiates has been found to suppress the production of the hormones, thus weakening the immune system and exposing a patient to possible recurrence of breast cancer long after treatment.

Further, it has been found that opiates encourage cancer cells to spread through the body long after treatment. What usually happens is that a few cancer cells may be circulating in the body after treatment of breast cancer. Opiates do have a direct effect on these cells in the body. It is this effect that may encourage the cells to spread and redevelop into new cancer growth over eth course of time.

Use of opiates as part of the standard therapies used to treat cancer is set to continue. On the other hand, fears about its association with recurrence of breast cancer will linger. What this calls for is careful and judicious use of the right therapies in treating cancer. AWAREmed Health and Wellness Resource Center has been known as a leading centre for cancer treatment and management for a long time. We run a range of highly specialized services in cancer diagnosis, treatment and overall care of patients. Our focus is on using alternative therapies to boost the effectiveness of other methods used in standard therapies. The result of this is your overall recovery and wellness within the shortest time possible.

Breast Cancer And The Use Of Opiates

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