Tag Archives: Cellular respiration

Salicinium Therapy for Cancer Treatment

December 11, 2014

Curing Cancer? Salicinium Therapy for Cancer Treatment

Cancer is a common health condition that continues to claim the lives of the old as well as the young. Basically anybody is at risk of getting cancer. Research has shown that one in every three people will develop a form of cancer.

It is a condition that affects the functioning of cells in the body. There are so many types of cancers today. Cancer results in cells growing uncontrollably. The condition has been associated mostly with lifestyle. Medical experts therefore believe that adjusting your lifestyle will reduce your risk of being sick. I am talking about adjusting to a healthier diet, exercising regularly and quitting habits like smoking.

Your health is in your own hands and you can make that leap of faith by choosing to lead a normal healthy life. Your body reacts to how you treat it. If you chose to get plenty of exercise once in a while or eating the right kind of diet, then the more likely you are to remain healthy.

salicinium

Going for regular medical check-ups will help diagnose health problems before they become something big to deal with. Being diagnosed with cancer for instance doesn’t mean a death sentence. It can be cured if detected early and there are so many treatments out there that will help you lead a normal life even with cancer.

You won’t lose anything by going to the doctor once in a while for general medical check-up. Instead, it will give you the satisfaction that you are leading a healthy life. If any problem was to be detected, the doctors will start the treatment early.

The most common form of cancer treatment is surgery. It involves removal of the cancerous tumor before it spreads to other parts of the body. Other forms of treatment that may come after or to replace surgery include radiation therapy, chemotherapy, gene therapy, stem cell transplant and hormone therapy, among others.

The symptoms of cancer can develop for years. Diagnosis of the disease takes a few weeks. Most patients do not realize that they are developing cancer until the condition becomes severe. This is why I maintain that regular visit to the doctor will do you no harm.

How Cancer Occurs

Aerobic respiration is a process where cells take in glucose and break it down in the presence of oxygen to form energy. This energy is needed for the various functions of the body. Glucose is more efficient when there is oxygen.

When oxygen is absent, it results in anaerobic respiration. Here instead of sugar in this case glucose being broken down to energy, the glucose is fermented. Fermentation occurs in conditions where there is sugar but no oxygen.

This is how cancer occurs. The cancerous cells thrive in such conditions. Fermentation also results in a drop in pH level of the blood leading to acidic conditions. Cancer is one of the fermentation diseases. Some of the other known diseases of fermentation include athlete’s foot, Candida albicans or even fungal infections affecting the lungs or other tissues.  These kinds of diseases can lead to untold suffering and severe pain.

Salicinium in Cancer Treatment

saliciniumSalicinium is a plant extract that is very natural. It has been used for years in the fight against cancer. It is one of the complex sugar molecules. Glycolysis is a natural phase of both aerobic and anaerobic respiration. Cancerous cells rely mostly on glycolysis.

Research has shown that salicinium contains compounds that can stop the first phase of glycolysis without necessarily having an effect on the other part. In short it can be able to stop the oxygen independent part that leads to fermentation.

This happens by stopping the fermentation process. Generally the fermenting cells here are the cancerous cells. This natural plant extract can alter anaerobic respiration by targeting fermenting cells and stopping anaerobic respiration in them.

It is efficient since it does this without destroying the healthy cells. It main target is only on the fermenting cells and not the healthy ones.

Unlike other forms of cancer treatment like chemotherapy which can end up destroying even the healthy cells, salicinium therapy works on the contrary. It ensures that the healthy cells are untouched. This allows them to continue performing all the necessary functions in the body.

However, it should be noted that salicinium does not necessarily destroy or kill the fermenting cells. The immune system is the only on that can do this. All this therapy does is stop fermentation by allowing cells to go back to their normal functioning. This in return boosts the immune system to destroy the fermenting cells which in this case do not perform the expected functions of cells.

In normal conditions the immune system aids in generation of new cells to replace the old and worn out ones. When silicinium stops the fermentation process of the cells it gives way for the immune system to generate new cells to replace them. This gets the body back to its healthy state.

What makes this kind of cancer therapy efficient is its ability to target only the affected cells. It does not lead to destruction of normal cells.  It should however be used in right amounts and only the correct form of the molecule should be used.

Dr. Dalal Akour has had many years of experience with patients with terminal illnesses including cancer. With this kind of experience, she has improved the quality of lives for many people. You too can be part of her life transforming journey. Contact her today to get more medical advice on this as well as other health awareness tips.

Curing Cancer? Salicinium Therapy for Cancer Treatment

 

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DCA As a Glycolitic Inhibitor

August 17, 2014

DCA  As a Glycolitic Inhibitor Helps In Fighting Cancer

DCAThe oncologist will tell you that finding a treatment that is effective in killing the cancer cells while safe on the healthy body cells was the biggest problem in the field of oncology. The cancerous cells just as much as the healthy cells need nutrients to continue living.  The oncologists plus other medical researchers have noted that the best way to treat cancer without affecting the healthy body cells is to deny them the nutrients supplies so that they can be starved to death. The cancer cells and the body cells require glucose from which they can make the ATP energy that they need to survive on. This made it hard to deny the cancer cells their nutrient supplies while leaving the healthy body cells nutrient supply unaffected. But this was in the past. Cancer researchers have found some existing differences between the survival mechanisms of the cancerous cells and the healthy body cells. Otto Warburg discovered that the cancerous cells depended entirely on the glucose to survive without which it could not live while the healthy body cells could make other sources of energy and continue living even when the sugar sources of energy were withdrawn. This discovery has led to more selective killing of the cancer cells without affecting the living body cells. The cancerous cells undergo increased glycolysis and rely on this pathway for generation of ATP energy as their sole source of energy for growth and survival but the healthy body cells are flexible to switch to other sources like fats.

Since the discovery by Warburg, oncologists have come up with different cancer therapies to help in killing the cancer cells effectively without hurting the healthy body cells. Overdependence of the cancer cell on the glycolitic pathway for generation of ATP energy as the sole source of survival has provided a great loophole through which the cancer cells can be selectively killed without affecting any other healthy cell by inhibiting glycolysis. To do this, glycolitic inhibitors must be used in order to weaken the cancer cells by blocking their nutrient supplies which is an anticancer itself thereby killing the cancer cells more effectively.

Cancer cells are characterized by increased glycolysis therefore when glycolitic inhibitors are used the cancer cells have no other ways of survival therefore they will die out of starvation. This approach has also been applauded in killing of cancer cells with mitochondrial defects that have become resistant to chemotherapy and radiation therapy drugs.

It may not be easy to understand the molecular and biochemical mechanisms that lead to increased aerobic glycolysis in the cancer cells, the metabolic repercussions of this increased glycolysis is very clear. The malignant cells become dependent or other addicted to the glycolysis pathway as the sole source of ATP energy. Researchers opine that the increased glycolysis in cancer cells may be caused by such factors as; hypoxia, oncogenic signals as well as mitochondrial dysfunction.

It is a known fact that the cancer cells need more energy to survive than the healthy cells. In glycolysis the ATP produced per glucose are only 2 which means the cancerous cells must use lots of glucose to survive unlike in the oxidative phosphorylation which generates more ATP energy per glucose the . Here 36 ATP are produced per glucose therefore small amount of glucose is needed for survival. So without glycolitic pathways the cancer cells are doomed.

In case of is glycolytic inhibition the healthy body cells will be able to adapt to other metabolic pathways to generate the ATP energy through the TCA cycle and oxidative phosphorylation in the mitochondria. The cancer cells however cannot adapt to other sources of ATP hence will die as they will not be able to live without another source of ATP energy. The healthy body cells will be able to adapt to new sources of energy like fatty acids and amino acids to produce metabolic intermediates channeled to the TCA cycle for ATP production through respiration. Glycolysis inhibition is therefore a clever way of killing the cancer cells without harm on the healthy body cells.

DCA is an effective glycolytic inhibitor

DCA works in very interesting ways in inhibiting glycolysis. It only leaves one option left for cancer cells to survive on- depending on other pathways as opposed to glycolysis. The cancer cells cannot do that hence they are killed. The healthy body cells can adapt to metabolic changes unlike the cancerous cells. The first way through which the body cells get energy is through glucose oxidation which happens in the mitochondria of every cell in the body and requires oxygen. Glucose respiration is the mostly utilized form of metabolism in the healthy cells. However in absence of oxygen the cells turn to glycolysis which takes place in the cell cytoplasm for energy generation. Glycolysis does not avail adequate ATP energy for normal cells; however it is the best for cancer cells. Glycolysis depends on sugar. This gives the healthy cell advantage as they have a backup plan in case the oxygen supply is interrupted. However to oxidize glucose there must be pyruvate. Pyruvate entry into the mitochondria is inhibited by an enzyme known as pyruvate dehydrogenase kinase (PDK). In case the PDK is strong then it will limit the transportation of pyruvate into the mitochondria and the healthy cells will have to depend on glycolysis even in presence of oxygen but incase its weak the pyruvate will be transported with ease to mitochondria even when the oxygen is low.

DCACancer cells have the most active PDK than the healthy cells and they are adapted to glycolysis. When PDK is weak then the cancer cells are disadvantaged and this is what the DCA does. It weakens PDK forcing the cancer cells to rely on glucose oxidation which does not favor them. Hence they will starve and die.

Dr. Dalal Akoury (MD) is an experienced integrative cancer doctor that has helped many cancer patients in their fight against the disease. She has worked hard not only in treating the disease but also in availing informational support to cancer patients at Awaremed which has become a place called home for many cancer patients. Call on her now and get help on cancer.

DCA As a Glycolitic Inhibitor Helps In Fighting Cancer

 

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Glycolysis Inhibitors Help in Fighting Cancer

August 4, 2014

 

The Role of Glycolysis Inhibitors In Fighting Cancer

The best way of killing cancer cells is to starve them. This is the safest way of killing cancer cell as the normal healthy cells are not affected by this way of killing the cancerous cells. In the past it was a big problem finding a way of killing the cancerous cells without affecting the healthy body cells. This is because all the cancer cells as well as the healthy body cells depend on glucose as their energy source that they need to survive. However very many researchers have done work on the subject of cancer cell metabolism and the discovery by Otto Warburg that the cancer cells depended entirely on glucose for source of energy unlike the healthy body cells that can adapt to other sources of energy like fats helps a lot in selective killing of cancer cells without hurting the healthy body cells. The cancerous cells undergo increased glycolysis and rely on this pathway for generation of ATP energy as their sole source of energy for growth and survival.

Basing arguments on the Warburg effect, doctors have come up with different cancer therapies to help in killing the cancer cells effectively without hurting the healthy body cells. The cancer cell overdependence on the glycolitic pathway for generation of ATP energy as the sole source of survival has provided a great loophole through which the cancer cells can be selectively killed without affecting any other healthy cell by inhibiting glycolysis.

There are Glycolytic inhibitors that can be used in maiming the cancer cells by denying them their source of livelihood. By inhibiting glycolysis they exert an anticancer effect on the cancer cells hence help in killing the cancer cells.

Glycolytic inhibitors can be used mostly in fighting cancer cells that have mitochondrial defects or in hypoxic conditions. These cells often become resistant to conventional medication such as chemotherapy or radiation therapy. However increased glycolysis is a common characteristic of all tumor cells and glycolysis inhibition can be used in wide range in treating cancer patients.

Though it may be difficult to understand the molecular and biochemical mechanisms that lead to increased aerobic glycolysis in the cancer cells, the metabolic repercussions of this increased glycolysis is very clear. The malignant cells become dependent or other addicted to the glycolysis pathway as the sole source of ATP energy. Researchers opine that the increased glycolysis in cancer cells may be caused by such factors as; hypoxia, oncogenic signals as well as mitochondrial dysfunction.

The cancer cells have to access a reliable supply of glucose in order to live. Unlike oxidative phosphorylation which generates more ATP energy per glucose the ATP generation of ATP through glycolysis is too little. Typically oxidative phosphorylation produces 36 ATP per glucose while glycolysis produces 2 ATP per glucose. This therefore forces the cancer cells to eat more glucose for effective metabolism as well as to accomplish other activities. The cancer cells therefore need to maintain glycolitic activities in order to grow and live on.

This metabolic characteristic of the cancer cells has availed a better way of killing cancer cells. Researchers have now proved that by inhibiting glycolysis the cancer cell will stop production of the ATP energy that they depend on and so they will die out of starvation.

When there is glycolysis inhibition the normal body cells will be able to adapt to other metabolic pathways to generate the ATP energy through the TCA cycle and oxidative phosphorylation in the mitochondria. The cancer cells however cannot adapt to other sources of ATP as they have defects hence will die as they will not be able to live without another source of ATP energy. The healthy body cells will be able to adapt to new sources of energy like fatty acids and amino acids to produce metabolic intermediates channeled to the TCA cycle for ATP production through respiration. Glycolysis inhibition is therefore a clever way of killing the cancer cells without harm on the healthy body cells.

DCA as a Glycolysis inhibitor

The way DCA works as a glycolysis inhibitor is very interesting; it forces the cancer cells to generate ATP through glucose oxidation but the cancer cells are not able to do this and they get starved and die. The healthy body cells can adapt to metabolic changes unlike the cancerous cells. The first way through which the body cells get energy is through glucose oxidation which happens in the mitochondria of every cell in the body and requires oxygen. Glucose respiration is the mostly utilized form of metabolism in the healthy cells. However in absence of oxygen the cells turn to glycolysis which takes place in the cell cytoplasm for energy generation. Glycolysis does not avail adequate ATP energy for normal cells; however it is the best for cancer cells. Glycolysis depends on sugar. This gives the healthy cell advantage as they have a backup plan in case the oxygen supply is interrupted. However to oxidize glucose there must be pyruvate. Pyruvate entry into the mitochondria is inhibited by an enzyme known as pyruvate dehydrogenase kinase (PDK). In case the PDK is strong then it will limit the transportation of pyruvate into the mitochondria and the healthy cells will have to depend on glycolysis even in presence of oxygen but incase its weak the pyruvate will be transported with ease to mitochondria even when the oxygen is low.

Cancer cells have the most active PDK than the healthy cells and they are adapted to glycolysis. When PDK is weak then the cancer cells are disadvantaged and this is what the DCA does. It weakens PDK forcing the cancer cells to rely on glucose oxidation which does not favor them. Hence they will starve and die.

Dr. Dalal Akoury is an experienced integrative cancer doctor who has seen very many cancer patients journey to victory in their fight against cancer. She is available for consultations. Just call her now and begin your journey to victory against cancer.

The Role of Glycolysis Inhibitors In Fighting Cancer

 

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