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stem cell medication

Stem cell and future medication

August 23, 2016

Stem cell therapy is undoubtedly the most innovative treatment that is currently available. But it is easy to miss out on some important facts if you base your judgment on the controversies revolving around it.

You need to understand clearly that a lot of research is still going on to find out the limit this treatment can go without leaving out the potential benefits and threats. In this article, I’m going to take you through some few things you need to know about stem cells.

How are embryonic stem cells obtained? Does the procedure defy ethics?

An embryonic stem cell is simply a product of the embryo. But to get a working stem cell, the embryo must be obtained after the egg of a woman is fertilized by the sperm from a man. The fertilization can be achieved either in a laboratory or the body of a woman.

If the embryos that are obtained via a laboratory procedure aren’t placed in the womb of a woman, then they can be used for medical research. Instead of throwing them away, scientists choose to harvest these eggs from which they obtain the stem cells.

What to keep in mind is that stem cells are never acquired from the fertilized eggs that are inside the human body. They are obtained from a laboratory and multiplied using cell cultures. Once obtained, they are frozen and shipped to wherever they are needed for treatment.

Other sources for stem cells

Adult stem cells are also useful but are only used to reproduce cells of their kind. For example, if the adult stem cells are muscle cells, they can only differentiate to form muscle cells. However, some studies have shown that contrary to what the scientist are claiming, adult stem cells just like embryonic stem cells can differentiate into other cells, but this is yet to be confirmed. On the other hand, embryonic stem cells have the ability to differentiate into all kinds of cells.

Why is the world so concerned about stem cells?

Simple, stem cells have the ability to differentiate into other kinds of cells. This makes them quite useful in solving many other health complications affecting humans today. However, there are a few of those who don’t fully accept the use of embryonic stem cells due to other ethical issues. Due to this, President Bush decided to restrict the research to stem cell sources that are existing.

 

stem cell medication

The objective of stem cell research

Scientists are more interested in their ability to differentiate. The main reasons embryo makes the main target is the fact that it can create all kinds of human body cells. But to achieve this procedure, scientist are trying to figure out how genes make a decision of creating specific kinds of cells.

They are also more interested in the information targeting the change in cell development. Figuring out all these will help them come up with cures for birth defects as well as cancers. However, all this depends on several issues that need to be addressed by both the government and the scientists.

 

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Treatment of Osteoarthritis by Stem Cells and Scaffolds

August 19, 2016

Affecting over 20, 000, 000 Americans, Osteoarthritis remains to be one of the most popular forms of arthritis characterized by a breakdown of joints most commonly in the knees, hips, spine, elbows, ankles and shoulders that might result from stress or an injury.

A functional cartilage of any young adult who is healthy is composed of a matrix that contains a mixture of sugars, proteins, collagen, and water. In the matrix, we have the chondrocytes whose primary purpose is to make the matrix they exist in.

Cartilage can withstand any additional load put on it simply because it can go back to the way it was initially after the load is lifted. Trauma or anything close may damage cartilage. This changes the way it functions. To restore the cartilage back to its normal condition, the chondrocytes begins to involve the devastating enzymes. A series of reactions start to take place such as, the deformation of the bone that is underlying, joint lining and production of cytokines which are protein messengers that work best to stimulate the inflammation.

These processes encourage the cartilage to wear away followed by a deformity as well as chronic inflammation influenced by unusual activities at the joint. To treat osteoarthritis, health experts have involved a series of remedies that involve anti-inflammatory drugs free of steroids, physical therapies as well as injection of hyaluronic acid or corticosteroid to the joints.

 

stem cells

Stem cell therapy has with time gained some popularity for being among the best promising remedies for osteoarthritis as well as its ability to bring back the cartilage to full functionality. However, this doesn’t mean that a one-time stem cell application will do the magic.

There have been several tests that have been carried out to figure out how stem cells can work together with the scaffold to effectively activate regeneration of the cartilage.

Several reviews have targeted to explain the scaffold types that can be put to study. Among them are, biomaterials such as sugars, chitin, the cell walls of algae, silk, fibrin, collagen and more.  Seeded with several growth factors, the scaffolds works nest to stimulate the multiplication and division of stem cells while at the same time shielding them from being destroyed by a harsh environment which is the arthritic joint.

Now, to use autologous stem cells in modern clinical medicine, there is a need to involve fat as a scaffold for the matrix. Together with several growth factors obtained from the components of blood, the matrix activates the certain biometric scaffold as mentioned above.

 

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stem cell therapy

Stem Cell Therapy: Frequently Asked Questions

July 16, 2016

Stem Cell Therapy is characterised by controversies that emanate from several contra-findings. Currently influenced by political debates, it is hard to know what’s true and what is not. Here are some of the frequently asked questions about the topic.

1.    What is stem therapy?

Stem cell therapy is simply a procedure that involves the use of blank state cells to regenerate damaged tissues in both humans and animals. These empty state cells can change to other cells that include, bone, muscle, nerve as well as organ cells.

This gives them the ability to regenerate tissues that are damaged vital for treatments of several complications such as spinal cord injury, osteoarthritis, degenerative disc, motor neurone disease and many others.

2.    Is it legal to use embryonic cells?

Yes, it is legal. However, funding by federal governments only targets research that follows strict guidelines. It isn’t wrong to go beyond these guidelines, but doing this will be excluded from federal funding. President Obama tried to loosen these restrictions in 2009 without success.

According to law, research that involves creating new stem cell lines can receive federal funding. This means that carrying out the research outside the guidelines will require the organisation concerned to find its way of funding it.

3.    What is the response of proponents to embryonic stem cell criticism?

Proponents claim that destroying an embryo after extraction of stem cells isn’t unethical as it is claimed to be. This is because the embryo is often destroyed when the donor no longer needs them to reproduce.

When done with the embryos, the donors have an option of killing the ones left, donating them to other women in need of it or donating them to science. The embryos used in this procedure are the ones that were to be destroyed.

stem cell therapy

4.    Are there any other kinds of stem cell therapies?

Yes. There are other types of stem cell therapies that don’t use embryonic cells. Stem cells can also be obtained in other places that include, adult umbilical cords, bone marrow as well as blood. It has also been noticed that healthy human cells can also be engineered to function the same way.

  1. What is the reason of going on with the embryonic stem cell research that is controversial if the cells can be obtained from adults?

Unlike, adult cells, embryonic cells aren’t limited. Embryonic cells have the ability to become any other cells in the human body. Adult cells aren’t also dependable when it comes to creating new motor neurones. However, they can successfully work for replacing the spinal disc, bone tissue, cartilage or muscle.

6.    What are the risks associated with this therapy?

Currently, the research that has targeted the therapy is still shallow. However, it has been noticed that the practice can increase the risks of cancer in patients receiving the treatment. Cancer results from cells that multiply faster and cannot self-destruct even when something goes wrong.

Stem cells, on the other hand, stimulates rapid multiplication of cells, and they tend to be a little hesitant when it comes to self-destruction.

 

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Pre transplant test result in Stem cell transplant

February 28, 2016

Pre transplant test and procedures leading to Stem cell transplant: How to get ready

Pre transplant test

Pre transplant test and procedures leading to Stem cell transplant are just steps leading to your perfect health you deserve only if it is done professionally

From our previous article, we discussed about the stem cell transplant and the benefits attached to it and we now want to further the discussion by focusing on the pre transplant test and procedures leading to stem cell transplant. Experts from AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury are going to be very instrumental in helping us put all the facts around the pre transplant test into perspective. From experience doctor Akoury says that any person planning to undergo through stem cell transplant will have to undertake certain tests and procedures to ensure that their health and status are perfect for the process to begin. Besides, the individual must be physically prepared to go through the transplant. It is also important to note that this may not be a one stop evaluation as it may take a couple of days before it is proven beyond doubt that the patient is ready for the transplant. In addition to that a surgeon or radiologist will implant a long thin tube (intravenous catheter) into a large vein in your chest or neck. The catheter, often called a central line, usually remains in place for the duration of your treatment. Your transplant team will use the central line to infuse the transplanted stem cells and other medications and blood products into your body.

Pre transplant test and procedures leading to Stem cell transplant: Collecting stem cells for transplant

When the patient is now ready, depending on the situation an autologous stem cell transplant can be planned and if this is the case then the patient will undergo a procedure called apheresis primarily to collect blood stem cells. But before apheresis, the patient will first receive daily injections of growth factor to increase stem cell production and also to move stem cells into the blood circulation so that they can be collected. Doctor Akoury says that it is during apheresis, that blood is drawn from a vein and circulated through a machine. The function of the machine is to separates the blood into different parts, including stem cells. These stem cells are then collected and frozen for future use in the transplant with the remaining blood being returned to the patient’s body.

On the other hand in the event that an allogeneic stem cell transplant is planned, the patient will have to find a donor who will donate the stem cell for the transplant. This process is often called a stem cell harvest or bone marrow harvest. The donor’s stem cells will be drawn from their bone marrow or their blood. It is only at this point that your transplant will team make a decision on what is better for you based on your prevailing situation.

Pre transplant test and procedures leading to Stem cell transplant: The conditioning process

Before the commencement of the transplant, one must go through the pre-transplant tests and procedures and after all that is done the next step is known as conditioning. During this process of conditioning, the patient will be taken through mild chemotherapy and possibly radiation primarily to:

  • Destroy any cancer cells particularly if you are being treated for a malignancy
  • Suppress your immune system
  • Prepare your bone marrow for the new stem cells

The process of conditioning will differ from patient to patient depending on a number of factors, including your disease, overall health and the type of transplant planned. You may have both chemotherapy and radiation or just one of these treatments as part of your conditioning treatment. And like any other treatment the process of conditioning is bound to be some side effects including the following:

  • Organ complications, such as heart, liver or lung failure
  • Bleeding
  • Infertility or sterility
  • Nausea and vomiting
  • Infection
  • Anemia
  • Fatigue
  • Cataracts
  • Diarrhea
  • Hair loss
  • Mouth sores or ulcers

Because these side effects could cause discomfort to your health, doctor Akoury advices that you could to take some medications or other measures to reduce them (side effects).

Reduced-intensity conditioning

Based on your age and health history, it may be better for you to receive lower doses or different types of chemotherapy or radiation for your conditioning treatment. This is called reduced-intensity conditioning. Reduced-intensity conditioning kills some cancer cells and somewhat suppresses your immune system. Then, the donor’s cells are infused into your body. Donor cells replace cells in your bone marrow over time. Immune factors in the donor cells may then fight your cancer cells.

Pre transplant test and procedures leading to Stem cell transplant: What to expect

After conditioning, the stem cell transplant can take place. On the day of your transplant, called day zero, you are given the stem cells through your central line using a process known as infusion. The transplant infusion is painless. You are awake during the procedure. The transplanted stem cells make their way to your bone marrow, where they begin creating new blood cells. It can take a few weeks for new blood cells to be produced and for your blood counts to begin recovering.

Bone marrow or blood stem cells that have been frozen and thawed contain a preservative called dimethyl sulfoxide (DMSO) that protects the cells. Just before the transplant, you may receive medications to reduce the side effects the preservative may cause. You’ll also likely be given IV fluids (hydration) before and after your transplant to help rid your body of the preservative. Side effects of DMSO may include: nausea, fever, diarrhea, chills, hives and red urine. Remember it is not necessarily that everyone will experience side effects from the preservative some may not experience anything while for some people those side effects are minimal.

Pre transplant test and procedures leading to Stem cell transplant: After your stem cell transplant

Finally when the new stem cells enter the body, they will move down to your bone marrow and within a short time, they multiply and begin to make new, healthy blood cells through a process known as engraftment. And even though the new cells will be forming up it will take some time may be several weeks before the number of blood cells in your body starts to return to normal. This may differ with people as the case may thereby taking a little longer with some people. Nonetheless as a way of ensuring safety several days or weeks after the stem cell transplant is done, the patient will some tests to monitor their condition. During this period you may need to take some medications to help you manage any complications like nausea and diarrhea. Remember that after this is done you will need to be under close medical observation just to ensure that any arising complication is addressed in good time.

http://regenerativepotential.com/integrativeaddictionconference/

 

 

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Simple explanations about stem cell addiction therapy

August 4, 2015

Simple explanations about stem cell addiction therapy: Understanding stem cells

Simple explanations about stem cell addiction therapy

Simple explanations about stem cell addiction therapy can go along way in offering solutions to those who are struggling with all forms of addiction.

We are going to have a series of articles about stem cells as we progress, but in the meantime we begin by giving a simple explanations about stem cell addiction therapy a what really stem cell are? These (Stem cells) are elemental cells that can develop into any type of specialized cells on their own. It simply means that stem cell can become any of the over two hundred different cells in the human body (brain cell, kidney cell, lung cell etc.) and like I have mention, these cells have a unique ability for self- regeneration or renewal through mitosis (cell duplication). That ordinarily means that each cell is capable of producing more stem cells on its own. Doctor Dalal Akoury one of the most respected addiction expert’s reports that stem cells come in two major basic categories including embryonic cells which are withdrawn from the umbilical cord blood and adult cells extracted from the bone marrow adipose tissue or processed blood which are potentially used in medical practices.

Simple explanations about stem cell addiction therapy: Stem cell technology for addiction

Scientifically so many studies have established that more than fifty percent of addictions are as a result of genetic predisposition. For instance, children born out of drug addicts parents are 7-9 times more prone to developing an addiction in their life. We can say that their brain is prewired for drug abuse, alcohol abuse or any other substance abuse, and the danger is that even after they have been taken treatment therapy successful they may relapse into some other form of addictions meaning that they are genetically bound to such substances. Besides that even if a person have lower predisposition for dependencies, they may as well and up with some kind of addiction. How does that happen? Ordinarily these do happen by abusing any addictive substances and connecting it with joyful feelings, the effect of that is that we are training our brain to associate that substance with happiness and the consequences of that is, we will be motivated to seek for that substance more often thereby resulting to addiction.

Doctor Akoury from her many years of experience says that with all these practices taking place, it is almost becoming obvious that product of all these process which is  drug addiction becomes very difficult to treat irrespective of whether it is genetically imposed or acquired over time. The difficulty is coming because the brain in this case will need some kind of rewiring. When the brain chemistry has changed, what follows is that brain cells become addicted meaning that treatment must be performed on cellular level. That is the technicality we are likely to face from such experience however, the good news is that with the numerous researches done in the past decades experts have established that treatment can actually be successfully achieved with the application of stem cell therapy.

Simple explanations about stem cell addiction therapy: Stem cell addiction therapy as a method of treating drug and alcohol addiction

As we pointed out earlier, to successfully treat addictions, we need to approach the problem on a cellular level. Brain chemistry must be rebalanced and all the dead cells must also be replaced. According to the experts at AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury this can be achieved by transplanting cells into the section of the brain which controls reactions to various substances including drugs, alcohol or any other addictive substances. Stem cells then begin their reproduction and conversion into new healthy brain cells. The result of this will be the simultaneous replacement of old and corrupted brain cells whose life cycle has ended. The significance of this action will be that, that section of the brain is overwhelmed with healthy cells. With this practice being done from time to time, eventually, the rebuilding of that section of the brain that controls addictions will lead into complete healing.

The good news about stem cell addiction therapy is that it is the purest method of treating addictions since the process itself mimics natural development of the human body. It is the future of the addiction therapy practice in drug rehab centers, since it is non-toxic (no medication is used), it is painless (unlike some other methods) and above all it is very safe and successful. And now with this discovery of the most efficient and reliable treatment of addiction, we should all remain focus in pursuing our individual and collective objective of kicking out drug and alcohol addiction from our lives and societies. This new treatment technique will not be helpful if we keep the problem to ourselves. Denial is a very big impediment to the success of addiction therapy. Therefore if you or anyone you know a friend or a loved one is struggling with any form of addiction, they you own then a duty of care in ensuring that first you share what you now know and second being the connection point to their treatment process. You have a duty of encouraging them to accept that they have a problem and that the problem is not as a result of anyone’s weakness or weak character but on which is considered a disease. Denial will be there but giving up mush and should not be an option in this fight against substance abuse.

Finally make it up on yourself to share the challenges you may be experiencing with the experts at AWAREmed Health and Wellness Resource Center so that you can get all the techniques you need to win your friends over for treatment. When you have achieved that, then you can now schedule for an appointment with doctor Dalal Akoury either for yourself or on behalf of your loved ones so that a detailed evaluation can be done and you are put on the right treatment program that will leave you much healthier and ready to face life with confidence and live it to the fullest thereafter.

Simple explanations about stem cell addiction therapy: Understanding stem cells

 

 

 

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