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Unique Properties of Stem Cells

What Are The Unique Properties Of All Stem Cells?

Stem CellsThe stem cells have been hailed for their efficacy in treatment of certain diseases especially those that are degenerative in nature like the Parkinson’s disease, osteoarthritis and even the Huntington’s disease. To accomplish all its medicinal capabilities the stem cells must have certain properties that are not present in other body cells. They therefore differ from other cells in the body. The stem cells are available majorly in the bone marrows and the adipose tissues but can also be harvested from placentas after a safe delivery. The stem cells have three general properties regardless of their source. These properties are; they are capable of dividing and renewing themselves for long periods; they are unspecialized; and they can give rise to specialized cell types. It is these distinct characteristics of the stem cells that make them effective in treatment of degenerative diseases.

The other cells found in the body like the nerve cells, the muscle cells and the blood cells are not able to replicate themselves unlike the stem cells that are able to proliferate after long periods of time. Typically, a starting population of stem cells that proliferates for many months in the laboratory can yield millions of cells. What is more is that the daughter cells are capable of long term self-renewal giving rise to more unspecialized cells.

Despite the vast research that has been done on the stem cells and their ability to treat certain diseases there are some information that are still required which we can only hope that researchers will one day find an answer to. These questions are as follows:

  • Scientists are trying to understand two fundamental properties of stem cells that relate to their long-term self-renewal:
  • Why can embryonic stem cells proliferate for a year or more in the laboratory without differentiating, but most adult stem cells cannot; and
  • What are the factors in living organisms that normally regulate stem cell proliferation and self-renewal?

When these answers are addressed there will be a valid explanation to how cell proliferation is regulated during normal embryonic development or during the abnormal cell division that leads to cancer. Such information would also enable scientists to grow embryonic and non-embryonic stem cells more efficiently in the laboratory to help in treatment of diseases.

The stem cells are unspecialized

Stem cells remain unspecialized even after long hours in the laboratory after getting harvested. The scientists have spent years of research trying to find out factors that make the stem cells unspecialized and differentiating into different cell types. It took two decades to learn how to grow human embryonic stem cells in the laboratory following the development of conditions for growing mouse stem cells. In a similar manner the scientists must first understand the signals that enable adult stem cell population to proliferate and remain unspecialized before they will be able to grow large numbers of unspecialized adult stem cells in the laboratory for medicinal use.

The stem cells are not specialized and hence are not able to perform specific functions. Unlike heart muscle cells, the stem cells are not able to pump blood through the body, they can neither carry oxygen molecules through the bloodstream like red blood cells nor can they kill pathogens like the white blood cells but they can give rise to more of all these cells; they can form bone, heart muscle cells, blood cells and even nerve cells. So they are then unspecialized cells that have the unique ability to give rise to specialized and more vital functional specialized cells.

Stem cellsThe process through which undifferentiated stem cells give rise to specialized cells is known as differentiation. It is through this process of differentiation that the stem cells become even more specialized. Scientists are just beginning to understand the signals inside and outside cells that trigger each step of the differentiation process. The internal signals are controlled by a cell’s genes, which are interspersed across long strands of DNA and carry coded instructions for all cellular structures and functions. In contrast, the external signals for cell differentiation include chemicals secreted by other cells, physical contact with neighboring cells, and certain molecules in the microenvironment. The interaction of signals during differentiation causes the cell’s DNA to acquire epigenetic marks that restrict DNA expression in the cell and can be passed on through cell division giving rise to more specialized cells.

There are however some questions that should be addressed and these may include; Are the internal and external signals for cell differentiation similar for all kinds of stem cells? Can specific sets of signals be identified that promote differentiation into specific cell types? Finding answers to these questions may help scientists to find new ways to control stem cell differentiation in the laboratory, thereby growing cells or tissues that can be used for specific purposes such as cell-based therapies or drug screening.

Integrative Addiction Conference 2015

With these distinct characteristics of the stem cells especially their ability to give rise to different specialized cell types, the stem cells are a cutting edge to treatment of diseases. Degenerative diseases have debilitated many people but it is treatable. Dr. Dalal Akoury (MD) is an expert in integrative medicine and a founder of AWAREmed Health and Wellness Center located at Myrtle Beach South Caroline. Visit her for more information on most lifestyle diseases.

What Are The Unique Properties Of All Stem Cells?

 

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Foods That Help Boost Serotonin Level

Foods That Raise Serotonin Level

Serotonin is one of the most important neurotransmitters in the brain. Serotonin helps in regulation of mood and sleep. According to recent research findings, when the level of serotonin is below optimum it can cause increased incidences  of aggressive behavior. Low serotonin levels have also been linked to anxiety and depression. If the recent research findings have to be believed which of course they are, then low serotonin levels are dangerous as it may lead to suicidal acts. In terms of dieting, making sure you’re not serotonin deficient is vital because serotonin triggers satiety after eating. Depressed serotonin levels is the likely reason why the vast majority of people cannot stay on a very low carbohydrate diet for the long term without feeling an unavoidable need to binge which may lead to more complex disorders. In the brain the production of neurotransmitter happens naturally without intervention of any other drug, however when you have used the drugs of abuse for some time they will lead to depletion in the levels of the brain chemicals such as serotonin and dopamine. This therefore means that for healthy levels of serotonin to be achieved after use of drugs, there is need for replenishing and supplementing serotonin through diet. There are foods that are very helpful in raising the levels of serotonin . Here are some of them.

Serotonin

Fresh Vegetables

Fresh vegetables work in myriad ways to ensure good health. the greens are rich in various minerals and vitamins that go along way in boosting the levels of serotonin. some of the fresh vegetables that are actually beneficial in increasing the level of serotonin include Spinach which contains a substantial dose of folic acid. it  is also a wonderful source of the mineral magnesium, a natural anxiety combatant. Without enough magnesium in your diet, you may find it hard to concentrate in addition to being fatigued and irritable. other foods that are rich in magnesium and hence helpful in boosting levels of serotonin include; cacao, seaweed, bananas, orange, tree nuts, peanuts, whole grains, corn, cheese, eggs, milk, and white fish.

Fresh Fruit

Fresh fruits are rich in nutritional content. The fresh fruits are rich in vitamins that serve the purpose of rejuvenating the body and giving it a healing approach as well as protecting the body and restoring crucial neurotransmitters like the serotonin which therefore helps in ensuring good moods. fruits are rich in B3 vitamins. these fruits may include watermelon, peaches, bananas, cantaloupe, and avocado. Generally, the B vitamins are very essential in restoration of neurotransmitters especially after a period of long term use of drugs of pleasure that are known to disrupt the functions of the neurotransmitters.

 Apples

An apple a day keeps the devil away is a common adage. The health benefits of apples are many and this explains why it is always recommended for patients. A compound found in apples called “quercetin’ is an antioxidant that studies have shown may not only help in the prevention of cancer but may also play an important role in the prevention of neurodegenerative disorders. the medicinal abilities of this compound is confounding. It also helps in boosting serotonin as well as dopamine levels.

 Herbs that Boost Serotonin Levels:

SerotoninSt. John’s wort -St. John’s wort is effective against mild to moderate depression, alleviates anxiety, insomnia, and irritability and eases pain. It increases the level of serotonin in the brain as well.

Dandelion– This herb is widely used in Europe as an excellent liver detoxifier and mild diuretic. It increases the flow of bile and encourages both the transformation and transportation of nutrients. It has been used historically to treat liver disorders, arthritis and gout. In the addict it will ease the transportation of nutrients in the body and restore energy in the cells as well as boost the level of serotonin.

Cannabis- though known for all the wrong reasons, cannabis has very high medicinal content, however it is highly addictive and that dictates that it be used in moderation as unregulated use can cause addiction. It works in a way that it increases the levels of excitatory neurotransmitters like dopamine and serotonin.

Burdock– burdock has been used to treat other conditions ranging from arthritis to diabetes to hair loss, and it’s an active ingredient in some cancer treatments this herb is also good in resoring the levels of serotonin.

Ginseng–  contrary to what many people believe , ginseng does not only increase the level of serotonin in the body but also works in rejuvenating, restorative, boosts energy and vitality and is tonic to the brain. Ginseng is often prescribed for patients fighting depression which is a common symptom of withdrawal from drug use. This herb is a better therapy for those who are under physical, emotional, mental or spiritual stress as it is a very strong antidepressant and adaptogenic. Ginseng promotes strong nerves, sound sleep, improves memory, clear thinking and enhances concentration.

Use of drugs for along time causes damage to the neurotransmitters. apart from the foods and the herbs, you can also increase the level of serotonin by sunlight. Bright light increases the production of Serotonin in the body.  Basking in the sunlight can absolutely improve your mood and also soothe muscle aches. It is good to note that by increasing the level of serotonin in your body, you are setting good grounds for addiction treatment and recovery. However, these problems need to be treated effectively through integrative medicine. Dr. Dalal Akoury (MD) is an expert at this.  Call her on (843) 213-1480 for help.

Foods That Raise Serotonin Level

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Cancer Risk: Sugar and Insulin

Cancer Risk: Sugar and Insulin

Diabetes is a sugar disease. It is a disease in which the body does not produce insulin or make proper use of it. Insulin is useful in the body in utilization of blood glucose. It allows glucose to be absorbed in the cells to enhance the production of energy. In the condition of diabetes, insulin is not effective which results in the blood being saturated with glucose. This leads to high glucose levels in the blood.

Obesity is the major cause of diabetes. It induces the resistance of the body to insulin. When this happens, the body is not able to break down glucose into energy. This causes glucose to accumulate in the blood.

To make do with this insulin resistance, the pancreas ends up producing more insulin. This leads to a rise in insulin in the blood. This insulin production can go on for years but it is not indefinite. Eventually insulin production will wear out and this will result in blood sugar increase. When this happens, it is then that an individual is diagnosed with diabetes.

There are different kinds of diabetes in the world today. There is type 1 diabetes which results from the inability of the blood to produce the insulin hormone. Type 2 diabetes on the other hand comes about when the body is unable to properly utilize the hormone. Another type of diabetes is pre-diabetes. This results when the blood glucose levels in the blood are higher than normal although not high enough to become type 2 diabetes. The fact is that over 79 million Americans today are pre-diabetic.

Insulin and cancer

Diabetes and cancer

As is a link between sugar and cancer, there’s the same between diabetes and cancer. Diabetes has been linked to pancreatic cancer. It is in most cases a symptom of pancreatic cancer or a risk factor. Studies have shown pancreatic cancer can occur to patients who have heard diabetes for over five years. The research done on pancreatic patients who have had diabetes for less than five years was unclear if diabetes was in itself the cause of the cancer.

As a symptom for pancreatic cancer, studies have shown that onset diabetes in people who are over 50 years of age may be in itself a symptom. Abrupt changes in the levels of sugar in the blood in diabetics who had controlled sugar level is also a symptom of pancreatic cancer.

Insulin Resistance Link to Cancer

This link may be related to the high level of insulin compensation. Obesity causes the body to resists insulin and this causes the pancreas to produce more insulin. This leads to increase in insulin levels in the blood. Insulin contributes greatly to the growth of body tissues. It increases with increase in essential nutrients and reduces when the body is derived of these nutrients.

Insulin may cause cells to rapidly increase. This occurs when insulin causes an increase in insulin-like growth factors (IGF). It could also cause cells to become more sensitive to other factors of growth. One characteristic of cancer cells is their ability to uncontrollably grow and become resistance to agents of cell death.

Growth factors play a major part in the growth of cancer cells as well as their progression. Past studies have shown that people with high levels of insulin-like growth are in more risk of developing, breast, colon or prostate cancer.

Resistance to insulin is characterized by the cells losing their sensitivity to the effects of insulin to aid in the absorption of glucose into the cells. Although this is so, it continues to promote the growth of cells in the body. Only the ability of insulin to transport glucose is affected.

The resistant state of insulin promoted by diabetes may in this case promote the development of cancerous cells. As the amount of insulin increases in the blood, so does its ability to induce cell growth. When this happens it leads to a cancer characteristic of uncontrollable growth of cells. As the pancreas continues producing insulin an individual may not get diabetes but he/she increases the rate of getting cancer.

sugar and cancer

Sugar and Cancer

When most of us hear about sugar we instantly think about the white substance we take in our beverages. Sugar has been linked to causing cancer. So what do most of us do? We cut out the sugar in our body including those that are essential. We cut out eating fruits such as oranges that have natural sugars.

You end up depriving your body of essential nutrients such as fibers found in fruits. However, sugar does not necessarily mean what you take in your tea or in fruits or soft drinks. It is widely used to describe those sugars in our body. Sugar also called glucose is very necessary for a healthy you. It is broken down into energy hence you are able to do those daily task.

High blood levels in the blood cause diabetes. This results in the insulin not being produced or appropriately used. When this happens a person is said to be diabetic. Sugar goes back to the case of diabetes and as seen it can increase a person’s risk of cancer.

Dr. Dr. Dalal Akoury has had years of experience with patients with cancer as well as diabetes. She has vast knowledge about sugar and insulin and their link to cancer. Just visit www.awaremednetwork.com for more expert opinion on this topic and more health tips.

Cancer Risk: Sugar and Insulin

 

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Understanding Hot Flashes And It’s Treatment

Understanding Hot Flashes And It’s Treatment

hot-flashesHot flushes sometimes called hot flushes refer to a quick sensation of heat and sometimes a red, flushed face and sweating.  This is a common problem, however the exact cause of hot flashes is not known, but may be related to changes in circulation that take place during menopause. Hot flashes happen when the blood vessels near the skin’s surface dilate to cool. A woman may also sweat to cool down her body. And some women have a rapid heart rate or chills. Hot flashes with sweating can also happen at night. These are called night sweats and may make it harder to sleep. Hot flushes may also be accompanied by a red neck. When affected the period that it takes to ease vary among women who are going through menopause. In some women the hot flashes may disappear after a week while in other women it will affect them for life. Hot flashes become less severe as time goes on.

 Symptoms of Hot Flashes in Women

Women may suffer the following symptoms when hit by hot flashes

The frequency of hot flashes varies; sometimes you may have many hot flushes in a day while in other times you will have few hot flashes that may subside after few minutes. Though they can affect you during the day, they are more common in the night. When a person is affected by a hot flush it may take more than a year but most hot flashes will stop on their own within five years. Though hot flashes can subside on their own it is important to seek medical help if the symptoms become too severe.

Causes of Hot Flashes in Women

The exact cause of hot flashes in women has never been known. Not every decline in hormones results in hot flashes. It is also true that some women can go through menopause without suffering from hot flashes. However here are some factors that have been thought to have a great bearing on the cause of hot flashes.

Medications and Foods

When a drug or a type of food is introduced to the body the body will react to it in a way. There are some drugs and foods that are thought to induce hot flashes. These medications may include raloxifene (Evista) and tamoxifen (Tamoxifen and Nolvadex). There are some drugs that may also produce effects that mimic hot flashes. Spices used in preparing foods like peppers can also induce feelings similar to menopause induce hot flashes.

Stress and Anxiety

Stress and anxiety are some of the emotional causes of hot flashes. In reaction to external stimuli the body may release the stress hormones epinephrine and norepinephrine, which pump up blood flow and produce a warming sensation throughout the body. External stimuli such as migraine may cause heat that spreads all over your face.

Changes in hormonal balance

A change in hormonal surroundings may cause hot flashes even if it is not related to menopause. It is believed that hypothalamus plays a bigger role in occurrence of hot flashes. This is because it is the part of brain that deals with the body temperatures therefore any conditions that affects the hypothalamus can result in abnormal rise in temperatures such as hot flashes.

hot-flashes-symptoms

Other risks associated with hot flashes include;

  • Women who smoke are more likely to get hot flashes.
  • A high body mass index (BMI) is associated with a higher frequency of hot flashes.
  • Physical inactivity. If you don’t exercise, you may be more likely to have hot flashes during menopause.
  • More African-American women report menopausal hot flashes than do women of European descent. Hot flashes are less common in women of Japanese and Chinese descent than in white European women.
  • Alcohol- Alcohol may induce hot flashes in some people. Generally it is thought that using drugs of reaction may escalate the probability of hot flashes occurring.

Treatments for Hot Flashes in Women

There both orthodox as well as natural treatments for hot flashes. The natural treatment for hot flashes may include;

  • Evening primrose oil is a botanical herb that is often used to treat hot flashes, although there is no scientific evidence to support this. Side effects include nausea and diarrhea. Women taking certain medications, such as blood thinners, should not take evening primrose oil.
  • Although there is no scientific evidence to support using flaxseed, it is thought to decrease the symptoms of menopause, particularly hot flashes. It’s also known as linseed.
  • Soy products. Plant estrogens, found in soy products, are thought to have weak estrogen-like effects that may reduce hot flashes. Soy foods, not supplements, are recommended.
  • Black cohosh. Some studies suggest that black cohosh may be helpful in the very short term (6 months or less) for treating hot flashes and night sweats. Side effects include gastrointestinal upset.

Hot flashes are just some of the known symptoms that may trouble your life during menopause. Just like any other serious disease, it is necessary that you seek medical help. Contact Dr. Dalal Akoury an expert in natural therapies on (843) 213-1480 for help.

Understanding Hot Flashes And It’s Treatment

 

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Shared Medical Appointment: An Innovative Practice Model

Shared Medical Appointment: An Innovative Practice Model

A visit to a physician can always be such a tense moment. This is often characterized with a lot of anxiety and high expectations on the part of the patient. As a patient you want to get well. Yet you are also torn between the desire to get well and the fear of negative outcomes. It is usually worse with chronic conditions such as diabetes, heart conditions, asthma and ulcers.

It is based on such considerations and a hoard of others that it becomes necessary for the medical practitioner to adopt a method or initiate one that is more likely to make the medical appointment a less excruciating experience.

If the practitioner is able to turn the tension of the moment into a fun filled experience then it is a definite straight up success. It is not just the victim who enjoys the benefit of the experience with the medic, rather, the medical expert also stands to derive considerable gratification from handling a satisfied patient. No palm wetting, no forehead sweats; just a cool and non-tense exchange between a medic and his or her patient.

Impetus for the shared medical appointment approach

The shared medical appointment can be said to be resulting from the above line of considerations, to make the experience a natural process.

This shared medical appointment model, also referred to as group visits, cluster visits or problem solving drop-in group medical appointments (DIGMA) has been orchestrated with the core objective of inspiring the medical practitioner to come up with, implement and appraise shared medical appointments chiefly for patients with diabetes.

The model is basically an innovative approach that has a distinctly different methodology as opposed to the usual diabetes education classes. It involves a group of 12 to 16 patients meeting up with a doctor, medical assistant, behaviorist, nurse, and dedicated documenter for a time period of one and a half hours.

The traditional diabetic classes on the other hand usually address self-management techniques, the question of exercise and recommended nutrition for these patients. The group visits provide medical evaluation, the coordination and provision of precautionary services, mechanisms of adjusting medication, all which often miss in the ordinary diabetic classes.

The model succeeds in its conception as being innovative since it is found to improve the care offered to conventional patients of chronic disorders which primarily include diabetes as well as asthma, coronary disease, and urological conditions by aiding the use of available resources far more efficiently.

shared-Medical-appointments

The majority of successful shared medical appointment programs have included an element of case management and between-visit care coordination. The program is traditionally headed by a nurse, a physician or nurse practitioner.

If you set up a limited component of care management for group of patients who attend the programs of these cluster visits the program can be quite a useful step toward a wider use of care coordination within your field of practice.

A patient of diabetes may use these shared medical appointment programs in the place of a primary care or they can as well alternate the two sets of care arrangements: group visits and the one-on-one care units.

Other than the group education services typically offered in group visits, collective problem-solving, focused secluded or partially private health evaluations which allow for personalized medication adjustment; the programs may also involve ordering of referrals and preemptive services.

The sessions may always vary. They may go from one hour to even several hours depending with the physician-patient arrangements. Each session may have a varied number of attendees, with the typical maximum being 20 persons.

Benefits of the Group Visits Model

shared-medical-appointment Past medical records have indicated that patients generally enjoy interacting in a shared form of environment. There are less cases of tension associated with medical situations and this can always provide a lot of encouragement to those who attend the sessions while providing them with essential tips that may not be received in a short medical visit.

Physicians also benefit from the change of pace typical of these programs and have a chance to innovatively and much more thoroughly attend to the matters presented by chronic disorders which are common in most of the primary care circumstances.

Evaluations of the shared medical appointments have also reported a general increase in satisfaction levels of the patients and clinicians along with improved quality of care offered in the cluster situations. There have also been a reduction in the aggregate emergency section and specialist visits by these patients. This indicates a general possibility of increased perfection in following the directions provided during the sessions.

What makes the cluster visits even more beneficial is the communal environment created by the group approaches. Patients are able to share experiences freely and feel relieved by the existence of certain critical but shared experiences. It is human nature that you feel better when you know that you are not alone in your situation. Just the environment alone, the sight of many people supposedly in for the same course is enough to relax a patient’s nerves.

The patients attending the sessions are able to share their concerns collectively and get responses. This may help in two different ways. A patient who is either shy or simply unwilling to ask a pressing question may benefit from another patient asking the same. Secondly, a patient may get response to a question that he or she might have forgotten to ask the nurse or the physician in attendance. In general, the patients learn from the healthcare team in session, from one another as well as from the environment itself.

About the doctor

Dr. Dalal Akouri has years or experience attending to patients with various life threatening chronic illnesses and is proud to have improved the lives of such patients. You too can join this vast community of patients who have seen the fruits of her work by contacting het today.

Shared Medical Appointment: An Innovative Practice Model

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