How the use of opioids disturbs the cancer balance

What are opiods?

There are several important things about opiods that you need to know at this stage. First, it is important to note that strictly speaking, the term ‘opioids’ is used to describe a group of chemical compounds that are defined by two important characteristics: having chemical action that is similar to that of morphine and being made of a distinct chemical structure. For many of the compounds that are categorized under this umbrella, their structures vary. Whereas some have distinct alkaloid structures, others occur in the form of peptides.

The second thing is about the occurrence of opioids. Naturally, opioids are found in two distinctive forms: occurring freely in the environment and within the body of human beings. Although initially the possibility of occurrence of opioids within the body of humans was strongly refuted, rigorous research has indicated that indeed the human brain contains specific endogenous opioids that play important role in different functions.

The third thing regards the interaction of opioids with complementary chemical compounds. Further studies have indicated that there are compounds whose actions contradict that of opioids. Known as antagonists, such compounds play a highly important role in their interaction with opioids in relation to influencing particular processes in the body. We shall examine this subject later.

How are opioids used?

For years, opioids have been used for a range of functions. Basically, the use of opioids has been in the form of morphine, which is a commonly occurring plant. Morphine has been used for medicinal as well as recreational purposes for long. Since the use of the plant for medicinal purposes is what matters with regard to our discussion, we shall focus on it.

At the commercial level, morphine has actually been used to relieve pain in chronically ill patients. Take cancer for example, the disease has been known to produce intense pain in patients. To relieve patients of this, morphine-based painkillers are extensively used. This is one common and formal way in which morphine (a common source of opioids) is used for commercial purposes.

The ability of opioids in general and morphine in particular to act as a strong analgesic has been a subject of research for long. Studies have indicated that the compounds have specific effects on the nervous system which translates to drastic reduction in pain. This explains the popularity of morphine-based painkillers as the standard therapy for cancer patients who have undergone an operation as part of the therapy or simply those in advanced stages of cancer.

Therefore, whether for recreation or medicinal use, opioids, have been extensively used to relieve cancer patients of pain in the course of treatment.

How opioids act

Basically, the action of opioids on the body can best be understood when you understand what opioid receptors are. Your body is made of special compounds which act as receptors for opioids. The receptors are distributed in several parts of your body, with many of them being in the central nervous system. It is this phenomenon that explains why opioids have a very strong effect on the nervous system. Others are distributed in different parts of your body such as the lungs, liver and other internal organs.

There are several types of receptors. It is the interaction between specific opioids and receptors that causes particular feelings in the body. Whereas some receptors are meant to trigger feelings of relief when they come into contact with opioids, others are designed to trigger changes in other physiological processes when opioids are introduced. The interaction between opioids and receptors is an important process when it comes to how opioids may disturb the cancer balance in the body.

How do opioids disturb cancer balance?

Simply put, cancer balance is a situation in which the process of metastasis, angiogenesis and invasion of healthy body cells by cancerous ones is completely inhibited. Research has indicated that use of opioids as painkillers can disturb this balance, thus leading to development of cancer in the body. On the other hand, other studies have indicated that morphine, in particular, may have anti-cancer properties by inhibiting the cancer development process mentioned above.

One way in which opioids used as painkillers can disturb the cancer balance is by altering the normal functioning of the immune system. Since cancer development largely depends on the state of the immune system, any compound that alters the immune system can indirectly influence the possible occurrence, development and spread of cancer. From several studies conducted, it can be concluded that particular opioids are able to alter the normal functioning of the immune system, thus exposing a patient on whom they are used to cancer development.

On the other hand, some studies have indicated that morphine is able to induce natural cell death and, as a result, control the growth of cancer cells in the body. However, this property, which highly depends on a number of different factors such as the concentration of the morphine that is used and the state of the opioid receptors in the body, remains a subject of research. What you need to know is that there has been concrete evidence to the effect that the use of opioids for relief of pain in cancer patients may actually disturb the cancer balance and trigger fresh development of cancer. This happens because of the effect that opioids have on the immune system of the patient in the form of production and inhibition of production of important hormones.

Concluding remarks

Here at AWAREmed Health and Wellness Resource Center, we use the best approaches to administer alternative and complementary treatment of cancer to patients. Dr. Dalal Akoury is a specialist in this field. One thing, though, that sets her apart is her devotion to helping cancer patients successfully fight the devastating effects of the disease. Feel free to visit us in Myrtle Beach, South Carolina for a completely personalized administration of alternative and complementary therapies for cancer.