Category Archives: Obesity

Chemosensitivity Testing

July 20, 2014

RGCC chemosensitivity testing in cancer treatment

ChemosensitityTreatment of cancer involves the doctors analyzing some of the research findings and drug test results to give a patient a preferable cancer treatment that is thought of as the best for the type of cancer he or she has. The essence of personalized cancer treatment has attracted the attention of many doctors and the Research Genetic cancer center have  adopted a test; chemosensitivity testing that may help them know which treatment is good for a patient depending on the state and type of his cancer.

Chemosensitivity testing helps the doctors to know which drugs are good for your type of cancer. It involves extraction of the individual’s cancer cells and testing the cancer cells in lab to see which drug they are most responsive to. The chemosensitivity testing offers a guide to the doctors on which treatment methods to implement when treating the patient.

Chemosensitivity is more strategic and not haphazard and so is most effective as the drugs and the treatment procedures the patient is subjected to are pretested to know how effective they will be in treating the patient’s type of cancer.

RGCC testing may use blood or tissues and it is used to test the viability of the chemotherapy drugs in treating the cancer. It also involves genetic profiling of the cancer cell that will help the doctors decide on which treatment best suits the patient. It also checks on viability of other treatment methods that may be used alongside chemotherapy in killing the cancer.

CTCs and cancer stem cells

The circulating tumor cells (CTCs) plays a major role in metastasis. Scientists have established that metastasis can never take place without circulating tumor cells. They work as the single haematological neoplasias hence are a necessity for metastasis.

Tumor initiating cells are generally known as the cancer stem cells. They refer to tumor cells that have stems and are responsible for tumor progression. The circulating tumor cells and the cancer stem cells have similar genotypic and phenotypic characteristics.

The circulating tumor cells are very effective in spreading cancer in the body and helping in its growth. It has the ability to divide asymmetrically and give rise to many cancer cells. They can also circulate as non-proliferating tumor cells hence becoming resistant to chemotherapy however they can change from this state to proliferating pluripotent progenitor cancer cells due to dissemination.

 

To effectively treat cancer and avoid metastasis, the circulating tumor cells and the cancer stem cells needs to be targeted and eliminated. Treatment that is not strategic in targeting the circulating tumor cells and cancer stem cells may not yield long term health benefits.

What information can be found by identification and analysis of CTCs

The study of the circulating tumor cells provides very valuable information in tumor growth and progression as well as an insight of the long term prognosis. It will also give information to whether a specific patient will be able to respond to the treatment to be offered. The doctors will study CTCs to find out the possibility of the cancer cell reoccurring after treatment.

The doctors are finding CTCs identification and analysis as an effective tool in the diagnosis, monitoring cancer cell progression as well as cancer treatment.

Some of the information that doctors find through the identification and analysis of the CTCs include;

v  Possibility of long-term prognosis

v  Avails information that helps in identifying treatment method that a patients can positively respond to treatment

v  Possibility of the disease reoccurring after treatment

v  Evaluation of tumor regression at the right time

Chemosensitivity testing of CTCs and cancer stem cells

Chemosensitivity is a very effective way of cancer treatment. It is more personalized to fit an individual’s condition hence offer the best treatment. Chemosensitivity of CTCs is done by exposing monocultures of enriched CTCs to the available cancer therapy agents. The reaction of the cells to the treatment is analyzed. The doctors will choose the best treatment by checking on which cancer therapy agent induced apoptosis of cultured cells by a great extent. The pathologists can also learn the resistance ability of the CTCs to the cancer therapy agent by checking on how long they maintain normal behavior even after exposure to the cancer therapy agent.

Chemosensitivity helps the doctors in giving effective cancer treatments to patients as the tumor cells ability to resist certain drugs are tested before the drugs are given to the patients. The ability of the circulating tumor cells and the cancer stem cells to be resistant to the treatment offered makes treatment of cancer very difficult and this explains why some cancer patients have to go through numerous chemotherapies. Through testing in labs the doctors will be able to know the cancer treatment that will wipe out all the Circulating cancer cells as well as the cancer stem cells.

For individualized cancer treatment to be effective, the identification and analysis of the circulating tumor cells and the cancer stem cells helps a great deal. Haphazard administering of cancer drugs without testing the CTCs and the stem cells resistance ability to the drug will not work well.

Chemosensitivity testing of the circulating tumor cells and the cancer stem cells is an effective approach to cancer treatment as the CTCs and the cancer stem cells are responsible for cancer cell formation and metastasis hence must be dealt with if the disease is to be effectively treated. It also hastens the recovery process as opposed to the cases where drugs given are rendered ineffective due to the CTCs resistance. Dr. Dalal Akoury runs a website that equips people with relevant information about cancer. Check on her website regularly to benefit from her wealth of health knowledge.

RGCC chemosensitivity testing in cancer treatment

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Inflammation Linked To Cancer

July 19, 2014

Research Proves That Inflammation Causes Cancer

InflammationThere are very many causative agents to cancer but still with the global climate change and pollution to our environment, deforestation that has changed air composition in most parts of the world, even more cancer causative agents are yet to be known. Current research studies have linked inflammation to cancer.

 

Inflammation is one of the most effective defense mechanisms that our bodies use to protect us against the invasion of disease causing pathogens. Inflammation helps our bodies to eliminate bacteria and other chemicals that may cause disease in our bodies. Scientists say that without inflammation we can barely survive especially during infancy. So inflammations are typically beneficial to us but it also has a negative effect in our bodies. Inflammations can help in the formation as well as in the growth of cancerous cells. It may also help in metastasis.

 

When our bodies are invaded by foreign bodies, the bodies will react to counter the effects of the foreign body. An example is an open wound will open a path through which bacteria and other disease causing pathogens enter the body. As the bacteria enters through the open wound, the white blood cells respond by coming to the site of injury and initiates a war against the bacteria by the help of toxins that it uses to kill the bacteria. During this fight it can be seen that a swelling is developing around the injury, the area becomes red and painful. This condition should not last for long as it may cause damage to the healthy cells. After this the fighters leave the site leaving space for tissue repair and recovery agents to promote healing. This is how helpful inflammation is.

 

However incase the inflammation becomes too much, it may cause serious health problems. When inflammation becomes persistent, it may lead to diseases such as the rheumatoid arthritis as well as psoriasis. It may also cause cancer. Chronic inflammation leads to diseases such as pancreatitis and the Crohn’s disease which have been proved to increase one’s risk to cancer. Chronic inflammation has also been found to be the root cause of certain types of cancers stomach cancer and liver cancer.

 

How does inflammation cause cancer?

 

A new research study has proved that inflammation may cause cancer. The study done by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) found that inflammation triggers a rise in levels of a molecule called microRNA-155 (miR-155). The rise in levels of microRNA-155 (miR-155) causes a drop in the protein that are used in DNA repair and this results in higher rates of spontaneous gene mutations which finally leads to formation of cancer cells.

“Our study shows that miR-155 is unregulated by inflammatory stimuli and that over expression of miR-155 increases the spontaneous mutation rate, which can contribute to tumorigenesis,” explains Dr. Esmerina Tili a post-doctoral researcher who also authored the research findings.

 

“People have suspected for some time that inflammation plays an important role in cancer, and our study presents a molecular mechanism that explains how it happens.”

“Our findings also suggest that drugs designed to reduce miR-155 levels might improve the treatment of inflammation-related cancers,” Tili explains.

 

 

The researchers have so far proved that inflammation can cause cancer, so what next? How can we limit inflammations? You need not to worry nature has provided most of the powerful anti inflammation vegetables and fruits that will help you to avoid chronic inflammations and reduce your risk to inflammation induced cancers. Some of these are curcumin and Boswellia.

 

Anti-inflammation properties of Curcumin and Boswellia

 

Turmeric (Curcumin)

Turmeric is a member of the ginger family, turmeric has been highly valued for its many medicinal abilities, among most of its medicinal abilities is that it is very effective in reducing inflammations. Turmeric is a common spice to Indians who value it for its health benefits. Curcumin is the most active component of turmeric.  Curcumin is effective in reducing inflammations. It exerts its anti-inflammatory activity by inhibiting the enzymes and prostaglandins that are essential for inflammation.

Researchers at Baylor University Medical Center in Dallas conducted a research that involved dividing 45 patients with rheumatoid arthritis into three groups. One group received curcumin, the second group was given a standard rheumatoid arthritis drug and the third group was given both. After eight weeks, both the group who took curcumin alone and the group that got both the drug and the spice had a greater reduction in symptoms such as joint swelling and pain compared with those who only took the drug devoid of curcumin. It was also noted that those who were on the curcumin did not suffer any side effect as was the case with those who were under the standard drugs.

Boswellia

Boswellia is also known as frankincense. It was highly valued in the ancient times so much that when Jesus was born, the wise men brought him boswellia as a gift. This wonderful product has proved its medicinal value in treating various conditions. It is useful in reducing inflammations as well as repairing degenerated muscle tissues. Researchers have showed that it contains boswellic acids that are useful in reducing inflammations. The boswellic acids are also less toxic and do not cause any harm on the patient.

A research that was done to determine the treatment abilities of boswellia proved that it was effective. The research involved 30 patients that were suffering from osteoarthritis of the knee that were taken through placebo for 8weeks after which they were treated to boswellia for another 8weeks. The research found out that the patients’ conditions improved on the boswellia treatment than when on placebo.

To tame cancer you need reliable information. Dr. Dalal Akoury (MD) has a commitment of making this information available to you so that you can take care of your health better. Visit her website regularly and learn more.

Research Proves That Inflammation Causes Cancer

 

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Hallucinogenic Drugs

July 10, 2014

Hallucinogenic Drugs – Drug Addiction

Hallucinogenic

Drug addiction is and will never be good for human life it does not matter whether you are taking hallucinogenic drugs or not

The human senses can be affected in different ways and by different means. Consumptions of various drugs are some of the actions that have the adverse effects in the human senses. Among those drugs are hallucinogenic drugs, this is a collection of drugs with the capabilities of altering the human senses. They are also known as psychedelic drugs and are powerful to affect the perception of the world around us. They can also be very intimidating to the senses or rather change them in such a way that things become more extreme like the affected person can see dull colours much brighter and  occasionally even ‘see’ sounds or ‘hear’ colours. Besides affecting senses these drugs can also change their user’s moods thoughts and even behavior.

Some Hallucinogenic drugs group include

Hallucinogen is a collection of various drugs like: LSD, PCP, Magic Mushrooms, Mescaline, DMT. They also include ecstasy, cannabis especially the stronger varieties such as skunk and ketamine. It must be noted that some of these drugs originate naturally from vegetation’s for example cannabis and magic mushrooms whereas others are produced artificially from laboratories. The examples of laboratory drugs may include ketamine and ecstasy.

Street names of Hallucinogenic drugs

Like any other drug hallucinogenic drugs also have some street names associated with them these street names may include any of the following: Dope, Pot, Mushrooms, Acid, Special K, Angel dust, Trip, Blotters, Northern lights, Smarties etc.

How are hallucinogens used?

  • Lysergic acid diethylamide (LSD) is packaged in small squares of blotting paper or a sheet of small designs which the user drips onto their tongue. It can also be dropped into to sugar cube or used to produce capsules or tablets. When taken in whichever way it brings in alterations in human perception and feelings of being out of one’s body.
  • PCP or ‘angel dust’ is accessible in different forms and kinds which may include powder, tablets, liquid or crystals. It is ingested in the body through inhaling (snorted), smoked in cigarette, taken orally or injected.
  • Magic mushrooms are a wild form of fungus which is cultivated mainly in the UK and other parts of the world. The most common form is the ‘liberty cap’ although the ‘fly agaric’ variety is also used. They may be consumed raw even though many people prefer to add them to food or make them into a drink.
  • Mescaline is a more unusual form of hallucinogen which comes from a cactus plant.
  • DMT (dimethyltriptamine) is very similar to LSD. Besides being similar to LSD they are more powerful than LSD. It can be inhaled (snorted), smoked or injected and is less easy to get hold of than LSD.
  • Ecstasy is obtainable in tablets, capsules or a powder forms and is popular with clubbers as it enables them to dance for long hours. It boosts feelings of intimacy and closeness and is also known as the ‘love drug’.
  • Cannabis can be smoked or added to food e.g. ‘hash cakes’ and is taken as a means of relaxation although stronger varieties such as sinsemilla and skunk can cause mild hallucinations.
  • Ketamine is an anaesthetic drug originally designed for veterinary purposes but has been used by people for its hallucinogenic qualities. It acts in a very similar way to PCP and taken orally, as tablets or injected.
Effects of hallucinogenic drugs

As has been discussed the most noticeable effect one is that of altered perception, affected people report mind-altering effects in what they see, hear, smell or touch things which they think are there but in reality, don’t exist. These effects vary according to the substance taken, the quantity taken, how often, the environment, age and whether it is taken in combination with other drugs e.g. alcohol.

Some people may experience greater effects than others. One person may only have a minor experience which can be absolutely pleasurable often refered to as a ‘good trip’ whereas another person can experience a complete ‘out of body’ experience which is terrifying to say the least known as a ‘bad trip’.  Some of these effects only last for a short time but others can last for many hours.

People who experience altered perception can find themselves indulging in risky or dangerous behavior, for example believing that they are able to fly. It is not unknown for someone to jump from a great height because of a psychedelic experience.

Are hallucinogenic drugs addictive?

They tend to be used on an irregular basis only so addiction doesn’t occur but a tolerance can build up if the drug is used on a regular basis, for example cannabis or ecstasy.

These drugs have a strong psychological effect which often involves a change in the brain’s chemistry and structure which results in dependence.

People also find that they experience some rather unpleasant withdrawal symptoms if they stop which results in them continuing to take these drugs.

Other side effects include anxiety and depression and an unpleasant condition called ‘flashbacks’: this is where someone sees replays of their drug experience, weeks, months or even years after they took the drug. If any drug is causing you the mention side effects of hallucinogenic drugs you must not wait until it wears you down. It will be important that you seek help from the experts. This you can get conveniently at AWAREmed Health and Wellness Resource Center under Doctor Akoury’s care where total focus is on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE.

Hallucinogenic Drugs – Drug Addiction

 

 

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A Step Further to Controlling Addiction

July 10, 2014

A Step Further to Controlling Addiction-Parental Roles

Addiction

It is all about giving the best to your children. Nothing can be best like an addiction free life

The joy of having children is among other things is seeing them through life and transforming them to be useful and productive people in the society. This is very fundamental to all parents whether biological or foster. The common denominator in the up bring of children is to see them develop into worthy people in the tomorrows society. While this is everyone’s wish and hope, it’s not always the case thanks to addiction and problems related to drug addiction. This is becoming a common phenomenon today and it can affect the child at a very tender age that would ordinarily be seen to be easy to manage. The pain in much more inflicted when what you thought you could manage with ease become a pitfall that you cannot handle. This is what I want to share with you in this article so that we can together have the common approach in tackling addiction especially in our children.

Having been in this line I will be sharing some practical experiences I have had to deal with in this journey of finding solutions to drug addiction. It is becoming a normal practice for children as young as 15 years of age being addicted to drugs and very frustrating to control and advise appropriately by their parents. Many of us parents would put up family rules like imposing curfew but still all these rules are broken leaving us very devastated. Then the next cause of action would be to involve a professional for help. This indeed is necessary and visit to the professional office would engage you in discussion with the professional to get to the root cause of the matter and hence find working solutions to the problem at hand. All that these parents wants is solutions and quite often they will not be interested in the discussions because of fear that when the current situations with their children are out of control, it can be frightening, intimidating, and exceedingly stressful, especially when parents aren’t really sure of what their children is using.

 A Step Further to Controlling Addiction-Educating Parents about drugs

A knowledgeable parent will be able to offer the most immediate help because they will be able to recognize and label the condition. They will be able to notice the warning signs, suspicious behavior and get to know the differences between various drugs and their effects. This may be good for a start but often not enough. It is important to note that there will be no significant result is certain things are not changed because if nothing changes then nothing changes. As a professional how then will you help? It is not just about what you tell your patients it is all about change in thinking, behavior and attitude on the part of the parent and the loved one.

It is all about developing a different kind of mind-set which will help you have some control in situations like that. For instance illustrating from the experience of a given family therapist who specifically worked with individuals and families struggling with alcoholism, drug abuse, and dependence, who introduced an affectionately formula known as the “3-C’s” with this he would simply explain to parents and loved ones that:

  • You didn’t cause this condition.
  • You can’t control it
  • You can’t cure it.

This application might appear strange in some ways, however using rational and logical thought processes when dealing with irrational and illogical behavior e.g. alcoholics, substance abusers and out of control situations don’t usually work very well but here is a different way of looking at it, thinking about it, and managing it.

A Step Further to Controlling Addiction-Working with Addicts

A common scenario in working with individuals and families around alcohol/drug abuse and dependence looks something like this:

  • The abuser of the substance usually ends up in trouble in their environment be it at school, work, legally or in relationships within the family and outside the family.
  • Because of their drinking and drug use, and their out of control behavior they become the focus of attention and considered as the problem or troublemaker.
  • In the treatment world they are called the identified patient but to the family these individuals have issues which need fixing for the family can get their normal lives back.

Much of the energy and attention is put on the addicted patients to change their “crazy” behavior. The problem is that many at times they are not able to at that point in time, meaning that you will be asking someone who is out of control to take control. It normally don’t work that way and the condition continues to deteriorate until someone else take that control normally the court, police or families members.

Therefore if the 3-C’s say “you can’t control it,” what then do you control? Well exercise of control may be done if pressure is exerted upon an individual like threat of being put jail, job loss, divorce or eviction this way they may consent to go into treatment which will, hopefully, begin the process of change desired. Keen note should be taken as consenting to treatment may be used as an escape from the current situation (pressure) and once it ends the individual quickly returns to their prior behaviors and lifestyle.

Treatment is very vital, but it is has its limitations, it is only the beginning. If all the underlying conditions like stressors, relationships, etc. in a persons’ life remain unchanged, returning from treatment and sustaining that positive change may be very difficult. Many families believe that by sending someone for treatment will cures them and that during the treatment period they will be free from the crazy behaviors of the patient. That should not be the case, for lasting recovery it is important that the family get involved in the whole process that is before, during and after treatment.

A Step Further to Controlling Addiction-The family Dynamics

It can be easy to complain of your loved one addiction condition and their state of being out of control. But the families always miss a point it is unusual that one particular family member would be out of control for no reason. The point is appreciating families and family dynamics is always complicated and difficult and to add alcohol and drugs further complicate the already complicated problem. Much as we have these substances around us many families do not full information about alcohol and drug abuse and addiction. This deficiency of information leads to confusion and fear when a member of the family is addicted to any substance and so there is great need of creating awareness in all the family units. Finally realizing that there is an information gap Dr. Dalal Akoury, Founded of AWAREmed Health and Wellness Resource Center a facility of plenty you can ask for. Doctor Akoury is a medical doctor with decades of experience in addiction and together with her team of experts they are offering exclusive NER Recovery Treatment to everyone the world over. Your socials status does not matter everybody is welcome including physicians and health care professionals. You will not only be treated but will also be educated through trainings, clinical apprenticeships, webinars and seminars. This is an opportunity for you welcome and be a part of this truly successful and fast addiction recovery treatment.

A Step Further to Controlling Addiction-Parental Roles

 

 

 

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Essentials of Relapse Eradication

July 4, 2014

Essentials of Relapse Eradication-Drug Addiction

Relapse

All was well until your old supplier appeared. Drug addiction recovery is possible but is frustrated by relapse. Keep new friends and you will make it.

In making effort to root out drug addiction from our systems and by extension to the society at large one of the biggest challenges we are likely to face is that of relapsing along the way. For us to achieve our objective for eradicating the problem of addiction successfully then it is proper that we analyze this topic with a view of understanding its consequences and how to contain it. Because of this great interest relapse is going to form the basis of our discussion in this article. Therefore what is actually the meaning of relapse? It basically falling back to something that you have made effort to disassociate with or from, that is to say falling or sling back into a former or old state, practice, a vice, error, wrongdoing or just backsliding into illness after recovery. From the definition it is all about fall back but for our case in this article we will concentrate on the health aspect of it as we progress with our quest to understand relapse.

Relapse is a significant factor in the process of addiction recovery which many patients fall prey to however when it happen it is important that patients should not contemplate this as an admission of failure or point of weak character. Emphasis should be made to the effect that discontinuing an addiction to drugs, alcohol, nicotine etc. is a tedious, difficult and take a long process which would ordinarily require soundness and reasonable amount of courage and willpower to emerge the victor.

The challenge of relapse is such an uphill task not just to some but all patients whether in the rehab or not. Nonetheless many people who have succeeded will testify that they met several obstacles before their great success. It is therefore important to be positive all through even if they relapse once, twice or even several times the focus and determination to triumphant should be loaded for the ultimate result of beating an addiction.

We acknowledge that the whole process can be very frustrating to the patients themselves and even to their friends and relatives when they make and put a lot of effort in an attempt of trying to knock out their addiction related habits and then all over sudden they succumb in to the cravings. For sure this will be absolutely demoralizing and the patient being human will be right to feel discouraged because all the hard work and time they have invested appears to have been for nothing and that they may not beat their addiction but I want to give you hope that the effort is worth it and they must never look back. Relapse is real and is just one of the obstacle to overcome, so dear friend keep the good work you are almost there don’t give up because that is not an option your great life is a head of you and you are just about to repossesses it.

Essentials of Relapse Eradication-Don’t give up

Acknowledging that the process of addiction recovery will not be easy is a motivation factor. Many addicts go wrong in the process by giving in to temptations, dear friend as eluded in the above points turn around all the hindrances to be positive in this process. Take note that a relapse is a manageable risk and that you/we are all human and falling into temptations is normal. Desire to be transformative in approaching all matters of addiction recovery by igniting the light of hope and that despite the surrounding you are on course and progressing well with treatment plan. Take the greatest asset here which is your family and friend. They are all very much proud of you and are behind you and are supporting you all the way.

As we said before the journey will not be full of roses and so if for whatever reason you relapse and smoked a stick of cigarette or took a sip of alcohol don’t let this wear you down forge a head accept that it has happen and take note of when it happen, why it happen and what might have been the cause for it happening and finally how you purpose to prevent it from recurring again. With this notes taken take another step the moment you are able to soberly communicate, take it upon yourself to share with your psychotherapist or counselor and seek help from them on how to elude this from occurring again. Be sure that they are professionals and will be able to assemble a work plan containing ways of dealing with this new development. With this information your counselor is likely to speak to someone from your self-help group not to demine you but this is an indicator that you need a little more extra support and motivation to help keep you on the recovery track.

Essentials of Relapse Eradication-Essentials to help you avoid a relapse

There are steps you can take to prevent this from happening. These include:

  • Ensuring that you are not in close contact with those things which comprised your addiction, for example alcohol in the house or medicine bottles (e.g. painkillers).
  • Try and elude circumstances in which your emotions are involved which will cause you in seeing your addiction as the answer or a form of escape.
  • Try to elude events or social situations in which you may be attracted to relapse. For example if your colleagues ask you to go for a drink after work. It is better to decline until you are at a point where cravings are no longer a problem and you feel relaxed about having a soft drink with them.
  • If you were part of a group of friends who take drugs than avoid them and make new friends.
  • Keep a telephone number of an addiction help line or your local support group close to hand so that you contact them if you feel as if you are going to relapse.
  • Keep attending self-help groups, counseling sessions and support networks even if you feel as if you don’t need their help any more. They can often spot the signs of a potential relapse long before you do and will advise you on how to deal with this.
  • If you suffer a relapse be honest with yourself as to why it has happened, accept that it has and carry on with your treatment.

Finally we must work together to defeat addiction, relapse is sometimes very discouraging but with experts like Dr. Dalal Akoury, Founder of AWAREmed Health and Wellness Resource Center, the challenge will be professionally handled, look at a brief effort doctor Akoury is making together with her team of experience experts. They are offering exclusive NER Recovery Treatment to addicted patients globally as well to other physicians and health care professionals through training, clinical apprenticeships, webinars and seminars, this is all you need and any qualified professional in all disciplines can now be a part of this truly successful and fast addiction recovery treatment.

Essentials of Relapse Eradication-Drug Addiction

 

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